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of 13
pro vyhledávání: '"Cody Fine"'
Autor:
Arlene Sereno, Brian Kuhlman, Xiufeng Wu, F. Huang, Micheal A. Batt, Steven M. Lewis, Andrew L. Glasebrook, Ricky Lieu, Cody Fine, Carina Torres, S.J. Demarest, J.R. Fitchett, Caroline Weldon
A myriad of innovative bispecific antibody (BsAb) platforms have been reported. Most require significant protein engineering to be viable from a development and manufacturing perspective. Single-chain variable fragments (scFvs) and diabodies that con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0588a462f07d25db3bbc907d734eae12
Publikováno v:
Viral Immunology. 19:722-733
Clinical myocarditis is a precursor to dilated cardiomyopathy and a principal cause of heart failure. Nearly 30% of all recently diagnosed cases of myocarditis are attributable to infection with coxsackie B virus (CBV), the most frequently associated
Publikováno v:
Clinical Immunology. 110:134-144
Epidemiological studies have associated coxsackie B virus (CBV) with the development of insulin-dependent diabetes mellitus (IDDM) in humans. Infections of genetically susceptible mice with CBV strain 4 (CB4) induce autoimmune diabetes. Herein, we de
Publikováno v:
Virology. 314(2):510-520
The induction of autoimmunity by viruses has been hypothesized to occur by a number of mechanisms. Coxsackievirus B4 (CB4) induces hyperglycemia in SJL mice resembling diabetes in humans. While virus is effectively cleared within 2 weeks, hyperglycem
Publikováno v:
Diabetes. 52:2025-2034
Pancreatic beta-cell antiviral defense plays a critical role in protection from coxsackievirus B4 (CVB4)-induced diabetes. In the present study, we tested the hypothesis that interferon (IFN)-induced antiviral defense determines beta-cell survival af
Publikováno v:
Journal of Clinical Investigation. 109:79-87
Publikováno v:
Journal of Autoimmunity. 16:211-217
The induction of autoimmunity by viruses has been attributed to numerous mechanisms. Coxsackievirus B4 (CB4) induces insulin-dependent diabetes mellitus (IDDM) in mice resembling the final step of disease progression in humans. Following viral infect
Publikováno v:
Nature Medicine. 6:693-697
Cardiovascular disease is one of the leading causes of death worldwide, and has been associated with many environmental risk factors1. Recent evidence has indicated the involvement of pathogens such as viruses as causative agents, and specifically id
Publikováno v:
Molecular immunology. 44(10)
Costimulation by B7-1 and B7-2 molecules results in divergent biological effects. This is particularly striking in the NOD mouse, since the lack of B7-2 leads to complete protection from autoimmunity, whereas the B7-1 deficiency causes exacerbation o
Publikováno v:
Journal of autoimmunity. 25(2)
Chronic myocarditis often progresses to dilated cardiomyopathy resulting in heart failure or cardiac transplantation. Viral infection is the most common cause of myocarditis and coxsackie B viruses (CBV) are the most frequently cited etiologic agents