Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Cody A Desjardins"'
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131619 (2015)
Externí odkaz:
https://doaj.org/article/378eff04c91f4dea9ed0348670c99c27
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127641 (2015)
The myocyte enhancer factor 2 (MEF2) transcription factor requires interactions with co-factors for precise regulation of its target genes. Our lab previously reported that the mammalian MEF2A isoform regulates the cardiomyocyte costamere, a critical
Externí odkaz:
https://doaj.org/article/76a0b370a215496a9be267b17f272cf2
Autor:
Nikolaus R McFarland, Hemi Dimant, Laura Kibuuka, Darius Ebrahimi-Fakhari, Cody A Desjardins, Karin M Danzer, Michael Danzer, Zhanyun Fan, Michael A Schwarzschild, Warren Hirst, Pamela J McLean
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86048 (2014)
Hsp90 inhibitors such as geldanamycin potently induce Hsp70 and reduce cytotoxicity due to α-synuclein expression, although their use has been limited due to toxicity, brain permeability, and drug design. We recently described the effects of a novel
Externí odkaz:
https://doaj.org/article/c78d459ac5334556a26f1b1a94649c90
Autor:
Sara Cipriani, Cody A Desjardins, Thomas C Burdett, Yuehang Xu, Kui Xu, Michael A Schwarzschild
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37331 (2012)
Urate is a major antioxidant as well as the enzymatic end product of purine metabolism in humans. Higher levels correlate with a reduced risk of developing Parkinson's disease (PD) and with a slower rate of PD progression. In this study we investigat
Externí odkaz:
https://doaj.org/article/9bb4fb14c8b84f4e841afaa3fe2e6353
Autor:
Diane E, Frank, Frederick J, Schnell, Cody, Akana, Saleh H, El-Husayni, Cody A, Desjardins, Jennifer, Morgan, Jay S, Charleston, Valentina, Sardone, Joana, Domingos, George, Dickson, Volker, Straub, Michela, Guglieri, Eugenio, Mercuri, Laurent, Servais, Francesco, Muntoni, Shande, Tang
Publikováno v:
Neurology
ObjectiveTo report safety, pharmacokinetics, exon 53 skipping, and dystrophin expression in golodirsen-treated patients with Duchenne muscular dystrophy (DMD) amenable to exon 53 skipping.MethodsPart 1 was a randomized, double-blind, placebo-controll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c84c101e1b3dd57b3ae451d3f1d9037
https://ora.ox.ac.uk/objects/uuid:a45c718a-1957-463b-bd36-efe91be71e85
https://ora.ox.ac.uk/objects/uuid:a45c718a-1957-463b-bd36-efe91be71e85
Autor:
Nelsa L. Estrella, Amanda L. Clark, Francisco J. Naya, Yevgeniy Maksimenko, Sarah E. Nocco, Cody A. Desjardins
Publikováno v:
Journal of Biological Chemistry. 290:1256-1268
Skeletal muscle differentiation requires precisely coordinated transcriptional regulation of diverse gene programs that ultimately give rise to the specialized properties of this cell type. In Drosophila, this process is controlled, in part, by MEF2,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac39311ea16b7017d5700bbcf98c4723
https://doi.org/10.1074/jbc.m114.589838
https://doi.org/10.1074/jbc.m114.589838
Autor:
Francisco J. Naya, Cody A. Desjardins
Cardiomyocytes acquire their primary specialized function (contraction) before exiting the cell cycle. In this regard, proliferation and differentiation must be precisely coordinated for proper cardiac morphogenesis. Here, we have investigated the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6bba73360e89324f9ae96deb189642
https://europepmc.org/articles/PMC5481567/
https://europepmc.org/articles/PMC5481567/
Autor:
Satz Mengensatzproduktion, Madakasira V. Padma, Philipp Mahlknecht, Klaus Seppi, Michael A. Schwarzschild, Neji Tebib, Gabor G. Kovacs, Arno Gasperi, Rajeswari R. Moganty, Heike Stockner, Vishnu Swarup, Ikhlass Hadj Salem, Imola Plangár, Fakhri Kallabi, Albert C. Ludolph, Dénes Zádori, Johann Willeit, Patrick Weydt, Péter Klivényi, Jason D. Warren, Druck Reinhardt Druck Basel, Werner Poewe, Amel Ben Chehida, Levente Szalárdy, Christoph Scherfler, Stefan Kiechl, Matthew P. Frosch, Thomas C. Burdett, Hassen Kamoun, Faiza Fakhfakh, Hadhami Ben Turkia, Gregorio Rungger, Cody A. Desjardins, Michael Nocker, Nikolaus R. McFarland, Ghada Ben Salah, László Vécsei, Achal Kumar Srivastava, Camilla N. Clark, Christoph Schmidauer
Publikováno v:
Neurodegenerative Diseases. 12:I-IV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcafd0d4b37a340db35123791c36cc17
https://doi.org/10.1159/000355887
https://doi.org/10.1159/000355887
Autor:
Nikolaus R. McFarland, Michael A. Schwarzschild, Xiqun Chen, Cody A. Desjardins, Thomas C. Burdett, Robert Logan
Publikováno v:
Biomedical Chromatography. 27:122-129
The purine metabolic pathway has been implicated in neurodegeneration and neuroprotection. High-performance liquid chromatography (HPLC) is widely used to determine purines and metabolites. However, methods for analysis of multiple purines in a singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::743d25f8465b9c67fc5abbd6a1661daf
https://doi.org/10.1002/bmc.2760
https://doi.org/10.1002/bmc.2760
The cardiomyocyte cell cycle is a poorly understood process. Mammalian cardiomyocytes permanently withdraw from the cell cycle shortly after birth but can re-enter the cell cycle and proliferate when subjected to injury within a brief temporal window
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52bb36beacc97f1cafa5ecd4e81bb54e
https://europepmc.org/articles/PMC4591820/
https://europepmc.org/articles/PMC4591820/