Multiomics surface receptor profiling of the NCI-60 tumor cell panel uncovers novel theranostics for cancer immunotherapy

Autor: Heumos, Simon, Dehn, Sandra, Bräutigam, Konstantin, Codrea, Marius C, Schürch, Christian M, Lauer, Ulrich M, Nahnsen, Sven, Schindler, Michael

Publikováno v: Heumos, Simon; Dehn, Sandra; Bräutigam, Konstantin; Codrea, Marius C; Schürch, Christian M; Lauer, Ulrich M; Nahnsen, Sven; Schindler, Michael (2022). Multiomics surface receptor profiling of the NCI-60 tumor cell panel uncovers novel theranostics for cancer immunotherapy. Cancer cell international, 22(1), p. 311. BioMed Central 10.1186/s12935-022-02710-y

BACKGROUND Immunotherapy with immune checkpoint inhibitors (ICI) has revolutionized cancer therapy. However, therapeutic targeting of inhibitory T cell receptors such as PD-1 not only initiates a broad immune response against tumors, but also causes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace5e1a1d00b8f2f1242e5e4f59cdf96
https://boris.unibe.ch/173707/1/s12935-022-02710-y.pdf

Additional file 5 of Multiomics surface receptor profiling of the NCI-60 tumor cell panel uncovers novel theranostics for cancer immunotherapy

Autor: Heumos, Simon, Dehn, Sandra, Bräutigam, Konstantin, Codrea, Marius C., Schürch, Christian M., Lauer, Ulrich M., Nahnsen, Sven, Schindler, Michael

Additional file 5: Figure S5. Boxplot showing MFIs of all Mouse antibodies without Mouse IgG3 antibodies.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d51f3e711cb719a93f53aa03ad6a9c1c

Additional file 7 of Multiomics surface receptor profiling of the NCI-60 tumor cell panel uncovers novel theranostics for cancer immunotherapy

Autor: Heumos, Simon, Dehn, Sandra, Bräutigam, Konstantin, Codrea, Marius C., Schürch, Christian M., Lauer, Ulrich M., Nahnsen, Sven, Schindler, Michael

Additional file 7: Dataset S1. Correlation antibody staining, dataset showing the correlation in antibody staining from two different biological replicates in 2 subsequent weeks.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b0866cc53f4ab7b6b1c70d2a1ec6dc

Additional file 6 of Multiomics surface receptor profiling of the NCI-60 tumor cell panel uncovers novel theranostics for cancer immunotherapy

Autor: Heumos, Simon, Dehn, Sandra, Bräutigam, Konstantin, Codrea, Marius C., Schürch, Christian M., Lauer, Ulrich M., Nahnsen, Sven, Schindler, Michael

Additional file 6: Figure S6. Boxplot showing MFIs of Mouse IgG3 antibodies only.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74627dbf8f9912d15c372e349896265e

Additional file 9 of Multiomics surface receptor profiling of the NCI-60 tumor cell panel uncovers novel theranostics for cancer immunotherapy

Autor: Heumos, Simon, Dehn, Sandra, Bräutigam, Konstantin, Codrea, Marius C., Schürch, Christian M., Lauer, Ulrich M., Nahnsen, Sven, Schindler, Michael

Additional file 9: Table S1. Table summarizing the results of the HPA analysis related to the biomarkers identified for renal cancer.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf8785b97d662ddbe4d0c00f585981fa