Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Coco De Koning"'
Autor:
Suze A. Jansen, Alessandro Cutilli, Coco de Koning, Marliek van Hoesel, Cynthia L. Frederiks, Leire Saiz Sierra, Stefan Nierkens, Michal Mokry, Edward E.S. Nieuwenhuis, Alan M. Hanash, Enric Mocholi, Paul J. Coffer, Caroline A. Lindemans
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110072- (2024)
Summary: The intestine is vulnerable to chemotherapy-induced damage due to the high rate of intestinal epithelial cell (IEC) proliferation. We have developed a human intestinal organoid-based 3D model system to study the direct effect of chemotherapy
Externí odkaz:
https://doaj.org/article/b237740e0ce446bdbb6f4231e7e5bc68
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The outcome of allogeneic hematopoietic cell transplantation (allo-HCT) largely depends on the development and management of graft-versus-host disease (GvHD), infections, and the occurrence of relapse of malignancies. Recent studies showed a lower in
Externí odkaz:
https://doaj.org/article/441a00d5c0ff42b59845682ac5965b87
Autor:
Coco de Koning, Julie-Anne Gabelich, Jurgen Langenhorst, Rick Admiraal, Jurgen Kuball, Jaap Jan Boelens, Stefan Nierkens
Publikováno v:
Blood Advances, Vol 2, Iss 5, Pp 565-574 (2018)
Abstract: Residual antithymocyte globulin (ATG; Thymoglobulin) exposure after allogeneic hematopoietic (stem) cell transplantation (HCT) delays CD4+ T-cell immune reconstitution (CD4+ IR), subsequently increasing morbidity and mortality. This effect
Externí odkaz:
https://doaj.org/article/39414988be6f4fef8073cbd663270820
Publikováno v:
Blood Advances, Vol 2, Iss 4, Pp 428-432 (2018)
Abstract: Human herpesvirus 6 (HHV6) viremia is a common cause of morbidity following allogeneic hematopoietic cell transplantation (HCT). We previously associated T-cell reconstitution with HHV6 viremia. Here, we investigated whether HHV6 viremia af
Externí odkaz:
https://doaj.org/article/c7f404a64b014e23a5147da9fa31732d
Autor:
Nienke de Haas, Coco de Koning, Stefania di Blasio, Georgina Flórez-Grau, I. Jolanda M. de Vries, Stanleyson V. Hato
Publikováno v:
Journal of Immunology Research, Vol 2019 (2019)
The STAT signaling pathway is important in dendritic cell (DC) development and function. Tumor cells can induce STAT signaling, thereby inhibiting DC maturation and immunostimulatory functions, leading to hampered efficacy of DC-based immunotherapies
Externí odkaz:
https://doaj.org/article/2220ee2324fd47f581475e6ddda98711
Autor:
Linde Dekker, Friso G. Calkoen, Yilin Jiang, Hilly Blok, Saskia R. Veldkamp, Coco De Koning, Maike Spoon, Rick Admiraal, Peter Hoogerbrugge, Britta Vormoor, H. Josef Vormoor, Henk Visscher, Marc Bierings, Marieke Van Der Vlugt, Harm Van Tinteren, A. Laura Nijstad, Alwin D. R. Huitema, Kim C. M. Van Der Elst, Rob Pieters, Caroline A. Lindemans, Stefan Nierkens
Publikováno v:
Blood Advances. 6:1969-1976
The addition of fludarabine to cyclophosphamide as a lymphodepleting regimen prior to CD19 chimeric antigen receptor (CAR) T-cell therapy significantly improved outcomes in patients with relapsed/refractory (r/r) B-cell acute lymphoblastic leukemia (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7908be72146f2f9270c912a748b9328b
https://doi.org/10.1182/bloodadvances.2021006700
https://doi.org/10.1182/bloodadvances.2021006700
Autor:
Alexandre G. Troullioud Lucas, Caroline A. Lindemans, Senthil Velan Bhoopalan, Rana Dandis, Susan Prockop, Dinesh Keerthi, Coco de Koning, Akshay Sharma, Stefan Nierkens, Jaap-Jan Boelens
Publikováno v:
Transplantation and Cellular Therapy. 29:S310-S311
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::595576a5dd72fc1ccb713417bb356f58
https://doi.org/10.1016/s2666-6367(23)00480-3
https://doi.org/10.1016/s2666-6367(23)00480-3
Autor:
Wouter J.W. Kollen, Jaap Jan Boelens, Caroline A. Lindemans, Arjan C. Lankester, Birgitta Versluijs, Dorine Bresters, Coco de Koning, Marc Bierings, Stefan Nierkens
Publikováno v:
Blood Advances, 6(6), 1719-1730. ELSEVIER
We prospectively studied clofarabine-fludarabine-busulfan (CloFluBu)-conditioning in allogeneic hematopoietic cell therapy (HCT) for lymphoid and myeloid malignancies and hypothesized that CloFluBu provides a less toxic alternative to conventional co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6483d664f0196a7bd75269bfcf33d4e1
http://hdl.handle.net/1887/3575907
http://hdl.handle.net/1887/3575907
Autor:
Ester Dunnebach, Celina L. Szanto, Miranda P Dierselhuis, Eveline M. Delemarre, Alwin D. R. Huitema, Coco de Koning, Stefan Nierkens, Jaap-Jan Boelens, Lieve G. A. M. Tytgat, Max M. van Noesel, Annelisa M. Cornel, Kathelijne C. J. M. Kraal, Michelle L. Tas, Sara M. Tamminga, Denise A. M. H. van den Beemt
Publikováno v:
Cancers
Volume 13
Issue 9
Cancers, Vol 13, Iss 2096, p 2096 (2021)
Volume 13
Issue 9
Cancers, Vol 13, Iss 2096, p 2096 (2021)
Simple Summary Neuroblastoma is a type of childhood cancer accounting for approximately 15% of childhood cancer deaths. Despite intensive treatment, including immunotherapy, prognosis of high-risk neuroblastoma is poor. Increasing amounts of research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e365b288eead6520804b62288370f8b0
http://europepmc.org/articles/PMC8123570
http://europepmc.org/articles/PMC8123570
Autor:
Madan Jagasia, Einat Galamidi Cohen, Jaap Jan Boelens, David Valcárcel, Caroline A. Lindemans, Stefan Nierkens, Uri Goshen, Daniela Cilloni, Karin van Veghel, Aridaman Pandit, Coco de Koning, Amelia M. Lacna, Weiyang Tao, John E. Wagner, Mitchell E. Horwitz, Patrick J. Stiff, Guillermo Sanz, Tony Peled, Rabi Hanna
Publikováno v:
Bone Marrow Transplantation
Scientia
Scientia
Immunologia; Recerca mèdica Inmunología; Investigación médica Immunology; Medical research Omidubicel (nicotinamide-expanded cord blood) is a potential alternative source for allogeneic hematopoietic cell transplantation (HCT) when an HLA-identic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b1c7f7eb023ed9548781a776d1bc74a
https://pubmed.ncbi.nlm.nih.gov/34312498
https://pubmed.ncbi.nlm.nih.gov/34312498