Výsledky vyhledávání - "Cockroach allergen"

Akademický článek

A steroid‐resistant cockroach allergen model is associated with lung and cecal microbiome changes

Autor: Nobuhiro Asai, Alexander D. Ethridge, Wendy Fonseca, Kazuma Yagi, Andrew J. Rasky, Susan B. Morris, Nicole R. Falkowski, Yvonne J. Huang, Gary B. Huffnagle, Nicholas W. Lukacs

Publikováno v: Physiological Reports, Vol 11, Iss 13, Pp n/a-n/a (2023)

Abstract The pathogenesis of asthma has been partially linked to lung and gut microbiome. We utilized a steroid‐resistant chronic model of cockroach antigen‐induced (CRA) asthma with corticosteroid (fluticasone) treatment to examine lung and gut

Externí odkaz: https://doaj.org/article/30e8a75ff6d64684a97b715c7d4cd382

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Type II alveolar epithelial cell aryl hydrocarbon receptor protects against allergic airway inflammation through controlling cell autophagy

Autor: Ji Wang, Yilin Zhao, Xin Zhang, Wei Tu, Rongjun Wan, Yingchun Shen, Yan Zhang, Ruchik Trivedi, Peisong Gao

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

RationaleAryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, has been considered as an important regulator for immune diseases. We have previously shown that AhR protects against allergic airway inflammation. The underlying mech

Externí odkaz: https://doaj.org/article/19ecf9869cd84b52aa23c5d5bf356609

Zobrazit plný text záznamu

Akademický článek

Cockroach exposure and perceived stress interact to predict clinical outcomes in childhood asthma

Autor: Felicia A. Rabito, Derek Werthmann, Hua He, Aubrey S. Madkour, Whitney D. Arroyave, Michelle L. Sever, Thomas A. LaVeist

Publikováno v: BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-8 (2021)

Abstract Background Nonpharmacologic interventions for asthma management rely on identification and mitigation of important asthma triggers. Cockroach exposure is strongly associated with asthma morbidity. It is also associated with stress, another r

Externí odkaz: https://doaj.org/article/6168057c55aa40869fcce5fac3001ed6

Zobrazit plný text záznamu

Akademický článek

Activation of aryl hydrocarbon receptor (AhR) in mesenchymal stem cells modulates macrophage polarization in asthma

Autor: Zhuang Cui, Yuan Feng, Danqing Li, Taoping Li, Peisong Gao, Ting Xu

Publikováno v: Journal of Immunotoxicology, Vol 17, Iss 1, Pp 21-30 (2020)

Macrophage polarization has been demonstrated to exert a vital role on asthma pathogenesis. Mesenchymal stem cells (MSC) have the capacity to modulate macrophage differentiation from a pro-inflammatory M1 phenotype toward an anti-inflammatory M2 phen

Externí odkaz: https://doaj.org/article/fd98f83729c84b17a56ad825de5d00f1

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Epithelial Aryl Hydrocarbon Receptor Protects From Mucus Production by Inhibiting ROS-Triggered NLRP3 Inflammasome in Asthma

Autor: Xinyue Hu, Yingchun Shen, Yilin Zhao, Ji Wang, Xin Zhang, Wei Tu, William Kaufman, Juntao Feng, Peisong Gao

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

BackgroundDespite long-standing recognition in the significance of mucus overproduction in asthma, its etiology remains poorly understood. Muc5ac is a secretory mucin that has been associated with reduced pulmonary function and asthma exacerbations.O

Externí odkaz: https://doaj.org/article/3fd14cf87caf4b32bf86593efa1e708d

Zobrazit plný text záznamu

Akademický článek

Allergological Importance of Invertebrate Glutathione Transferases in Tropical Environments

Autor: Josefina Zakzuk, Ana Lozano, Luis Caraballo

Publikováno v: Frontiers in Allergy, Vol 2 (2021)

Glutathione-S transferases (GSTs) are part of a ubiquitous family of dimeric proteins that participate in detoxification reactions. It has been demonstrated that various GSTs induce allergic reactions in humans: those originating from house dust mite

Externí odkaz: https://doaj.org/article/96209d2f56a746e39ca0b13787491758

Zobrazit plný text záznamu