Therapeutic immunisation benefits mucosal-associated invariant T-cell recovery in contrast to IL-2, GM-CSF, and rhGH addition in HIV-1+ treated patients: individual case reports from phase I trial

Autor: Cocker, ATH, Greathead, L, Herasimtschuk, AA, Mandalia, S, Kelleher, P, Imami, N

Mucosal-associated invariant T (MAIT) cell populations are reduced in frequency in HIV-1+ patients, and this disruption is associated with systemic immune activation. Reconstitution of MAIT frequency may benefit HIV-1-infected individuals; however, o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::fd7a6f917f5f161ba28f0d803207ce91
http://hdl.handle.net/10044/1/66925

The role of CD8+ T-cell clones in immune thrombocytopenia.

Autor: Malik A; Centre for Haematology, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom., Sayed AA; Centre for Haematology, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom.; Department of Medical Microbiology and Immunology, Taibah University, Medina, Saudi Arabia., Han P; Department of Pathology, Stanford University School of Medicine, Stanford, CA.; Department of Hematology, Shandong Province Hospital, Shandong First Medical University, Jinan, China., Tan MMH; Centre for Haematology, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom., Watt E; Specialist Integrated Haematology and Malignancy Diagnostic Service-Haematology, Great Ormond Street Hospital for Children, London, United Kingdom., Constantinescu-Bercu A; Centre for Haematology, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom., Cocker ATH; Centre for Immunology and Vaccinology, Imperial College London, London, United Kingdom., Khoder A; Centre for Haematology, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom., Saputil RC; Centre for Haematology, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom., Thorley E; Centre for Haematology, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom., Teklemichael A; Centre for Haematology, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom., Ding Y; Centre for Haematology, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom., Hart ACJ; Centre for Haematology, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom., Zhang H; Department of Pathology, Stanford University School of Medicine, Stanford, CA., Mitchell WA; Department of Immunology and Inflammation, Imperial College London, London, United Kingdom., Imami N; Centre for Immunology and Vaccinology, Imperial College London, London, United Kingdom., Crawley JTB; Centre for Haematology, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom., Salles-Crawley II; Centre for Haematology, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom.; Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St. George's, University of London, London, United Kingdom., Bussel JB; Department of Pediatrics, Weill Cornell Medicine, New York, NY., Zehnder JL; Department of Pathology, Stanford University School of Medicine, Stanford, CA., Adams S; Specialist Integrated Haematology and Malignancy Diagnostic Service-Haematology, Great Ormond Street Hospital for Children, London, United Kingdom., Zhang BM; Department of Pathology, Stanford University School of Medicine, Stanford, CA., Cooper N; Centre for Haematology, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom.

Publikováno v: Blood [Blood] 2023 May 18; Vol. 141 (20), pp. 2417-2429.

Natural LILRB1 D1-D2 variants show frequency differences in populations and bind to HLA class I with various avidities.

Autor: Liu F; Department of Structural Biology, School of Medicine, Stanford University, Stanford, CA, 94305, USA.; Department of Microbiology and Immunology, Stanford University, Stanford, CA, 94305, USA., Cocker ATH; Department of Structural Biology, School of Medicine, Stanford University, Stanford, CA, 94305, USA.; Department of Microbiology and Immunology, Stanford University, Stanford, CA, 94305, USA., Pugh JL; Department of Structural Biology, School of Medicine, Stanford University, Stanford, CA, 94305, USA.; Department of Microbiology and Immunology, Stanford University, Stanford, CA, 94305, USA., Djaoud Z; Department of Structural Biology, School of Medicine, Stanford University, Stanford, CA, 94305, USA.; Department of Microbiology and Immunology, Stanford University, Stanford, CA, 94305, USA., Parham P; Department of Structural Biology, School of Medicine, Stanford University, Stanford, CA, 94305, USA.; Department of Microbiology and Immunology, Stanford University, Stanford, CA, 94305, USA., Guethlein LA; Department of Structural Biology, School of Medicine, Stanford University, Stanford, CA, 94305, USA. libbyg@stanford.edu.; Department of Microbiology and Immunology, Stanford University, Stanford, CA, 94305, USA. libbyg@stanford.edu.

Publikováno v: Immunogenetics [Immunogenetics] 2022 Dec; Vol. 74 (6), pp. 513-525. Date of Electronic Publication: 2022 May 13.

CD56-negative NK cells: Frequency in peripheral blood, expansion during HIV-1 infection, functional capacity, and KIR expression.

Autor: Cocker ATH; Department of Structural Biology and Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, United States., Liu F; Department of Structural Biology and Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, United States.; Laboratory Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, United States., Djaoud Z; Department of Structural Biology and Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, United States.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON, Canada.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada., Guethlein LA; Department of Structural Biology and Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, United States., Parham P; Department of Structural Biology and Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2022 Sep 23; Vol. 13, pp. 992723. Date of Electronic Publication: 2022 Sep 23 (Print Publication: 2022).

Pregnancy Gestation Impacts on HIV-1-Specific Granzyme B Response and Central Memory CD4 T Cells.

Autor: Cocker ATH; Imperial College London, London, United Kingdom., Shah NM; Imperial College London, London, United Kingdom., Raj I; Chelsea and Westminster Hospital, London, United Kingdom., Dermont S; Chelsea and Westminster Hospital, London, United Kingdom., Khan W; Chelsea and Westminster Hospital, London, United Kingdom., Mandalia S; Imperial College London, London, United Kingdom., Imami N; Imperial College London, London, United Kingdom., Johnson MR; Imperial College London, London, United Kingdom.

Publikováno v: Frontiers in immunology [Front Immunol] 2020 Feb 11; Vol. 11, pp. 153. Date of Electronic Publication: 2020 Feb 11 (Print Publication: 2020).