Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Cochran SP"'
Publikováno v:
Biochemistry. 19:4892-4898
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9401aa18844dc8b746f12f3e3fd28723
https://doi.org/10.1021/bi00562a029
https://doi.org/10.1021/bi00562a029
Autor:
Darlene Groth, Karen A. Bowman, Stanley B. Prusiner, Cochran Sp, David C. Bolton, Michael P. McKinley
Publikováno v:
Biochemistry. 21:6942-6950
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285befcb48b5b5d5ec7604d43b7d39e5
https://doi.org/10.1021/bi00269a050
https://doi.org/10.1021/bi00269a050
Autor:
N I Mock, Darlene Groth, Cochran Sp, Frank R. Masiarz, Stanley B. Prusiner, Karen A. Bowman, Michael P. McKinley
Publikováno v:
Proceedings of the National Academy of Sciences. 78:6675-6679
The scrapie agent causes a degenerative nervous system disorder of sheep and goats. Considerable evidence indicates that the scrapie agent contains a protein that is necessary for infectivity [Prusiner, S. B., Groth, D. F., Cochran, S. P., Masiarz, F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7542e3aea244d58c80e7a0bfcec22c
https://doi.org/10.1073/pnas.78.11.6675
https://doi.org/10.1073/pnas.78.11.6675
Publikováno v:
Journal of Infectious Diseases. 138:396-400
Spleen weights and mitogen responsiveness of splenocyte cultures from scrapie agent-infected and control-inoculated mice were compared over two-month periods following inoculation. Splenocytes from Swiss, C57B1, and BALB/c mice were stimulated with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11096ed5156bd8abc6419f6b99275d33
https://doi.org/10.1093/infdis/138.3.396
https://doi.org/10.1093/infdis/138.3.396
Autor:
Darlene Groth, Karen A. Bowman, Cochran Sp, Stanley B. Prusiner, Kenneth C. Kasper, Michael P. McKinley
Publikováno v:
Proceedings of the National Academy of Sciences. 78:4606-4610
To probe the macromolecular structure of the scrapie agent and explore conditions for monomerization, the stability of the agent in low concentrations of inorganic ions was determined. A reduction by a factor of 10(5) in scrapie titer was found on ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4532f533c4c206ac92da8eb7cae5ec6c
https://doi.org/10.1073/pnas.78.7.4606
https://doi.org/10.1073/pnas.78.7.4606
Publikováno v:
Biochemistry. 17(23)
Sedimentation profiles of the scrapie agent in extracts of murine spleen and brain were determined by analytical differential centrifugation. Infectivity profiles of the agent from the two tissues were similar. Sedimentation of the agent was not subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b55b3e41722b493164769f41cfa10487
https://pubmed.ncbi.nlm.nih.gov/214106
https://pubmed.ncbi.nlm.nih.gov/214106
Autor:
Darlene Groth, Bildstein C, Stanley B. Prusiner, Frank R. Masiarz, Michael P. McKinley, Cochran Sp
The molecular properties of the scrapie agent were investigated by subjecting partially purified preparations to electrophoresis on agarose gels. When electrophoresis was performed at room temperature in the presence of sodium dodecyl sulfate (NaDodS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498e6d653d0e331fc28e159bfc3fab08
https://europepmc.org/articles/PMC349531/
https://europepmc.org/articles/PMC349531/
Autor:
Darlene Groth, Frank R. Masiarz, Cochran Sp, Stanley B. Prusiner, Michael P. McKinley, Hugo M. Martinez
Publikováno v:
Biochemistry. 19(21)
The scrapie agent causes a progressive degeneration of the central nervous system of animals after a prolonged incubation period. Measurements of incubation period length, defined as the time from inoculation to the onset of clinical signs of neurolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964a5b1416fa8ef3cea6cc8b343b8202
https://pubmed.ncbi.nlm.nih.gov/6775697
https://pubmed.ncbi.nlm.nih.gov/6775697
Autor:
Eklund Cm, Stanley B. Prusiner, Richard E. Race, W. J. Hadlow, Cochran Sp, Darlene Groth, Garfin De, Michael P. McKinley
Publikováno v:
Journal of neurochemistry. 35(3)
Some biochemical and biophysical properties of the scrapie agent in a partially purified fraction P5 from murine spleen are described in this communication. The agent was stable in the nonionic detergents Triton X-100 and Nonidet P40 and stable in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2bec5c872b4883e94dc427448829702
https://pubmed.ncbi.nlm.nih.gov/6778963
https://pubmed.ncbi.nlm.nih.gov/6778963
Publikováno v:
The Journal of infectious diseases [J Infect Dis] 1985 Nov; Vol. 152 (5), pp. 971-8.