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Atropselective Oxidation of 2,2′,3,3′,4,6′-Hexachlorobiphenyl (PCB 132) to Hydroxylated Metabolites by Human Liver Microsomes and Its Implications for PCB 132 Neurotoxicity

Autor: Eric V. Patterson, Jonathan A. Doorn, Coby Yeung, Brianna S. Cagle, Eric Uwimana, Xueshu Li, Hans-Joachim Lehmler

Publikováno v: Toxicol Sci

Polychlorinated biphenyls (PCBs) have been associated with neurodevelopmental disorders. Several neurotoxic congeners display axial chirality and atropselectively affect cellular targets implicated in PCB neurotoxicity. Only limited information is av

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7683b4f9f0139b49ea8c2a7a915325c
https://europepmc.org/articles/PMC6760323/

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