Zobrazeno 1 - 10
of 205
pro vyhledávání: '"Cobi J Heijnen"'
Autor:
Hanneke L D M Willemen, Annemieke Kavelaars, Judith Prado, Mirjam Maas, Sabine Versteeg, Lara J J Nellissen, Jeshua Tromp, Rafael Gonzalez Cano, Wenjun Zhou, Magnus E Jakobsson, Jędrzej Małecki, George Posthuma, Abdella M Habib, Cobi J Heijnen, Pål Ø Falnes, Niels Eijkelkamp
Publikováno v:
PLoS Biology, Vol 16, Iss 2, p e2003452 (2018)
Chronic pain is a debilitating problem, and insights in the neurobiology of chronic pain are needed for the development of novel pain therapies. A genome-wide association study implicated the 5p15.2 region in chronic widespread pain. This region incl
Externí odkaz:
https://doaj.org/article/66efd9c0e1c7495d85239fbfe2edd509
Autor:
Deodata Tijsseling, Maike Ter Wolbeek, Jan B Derks, Willem B de Vries, Cobi J Heijnen, Frank van Bel, Eduard J H Mulder
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192162 (2018)
Although postnatal corticosteroid (CS) therapy has well established beneficial effects on pulmonary function, it may also result in growth restriction during treatment. The course of early childhood growth is believed to predict cardiovascular and me
Externí odkaz:
https://doaj.org/article/2deb3cc8643d478aa2a8c57fd554c2ac
Autor:
Vincent D. Lai, Jensine Paoletti-Hatcher, E. Lydia Wu-Chung, Itee Mahant, Daniel L. Argueta, Kelly N. Brice, Bryan T. Denny, Charles Green, Luis D. Medina, Paul E. Schulz, Jennifer M. Stinson, Cobi J. Heijnen, Christopher P. Fagundes
Publikováno v:
Comprehensive Psychoneuroendocrinology, Vol 20, Iss , Pp 100271- (2024)
Caregivers for spouses with Alzheimer's disease and related dementias (ADRD) experience drastic changes in the marital relationship that may put them at risk for worsening well-being. Perceived partner responsiveness, or feeling cared for, understood
Externí odkaz:
https://doaj.org/article/564cfbb0c1a147eeb19aca2953cc04ba
Publikováno v:
Comprehensive Psychoneuroendocrinology, Vol 20, Iss , Pp 100269- (2024)
Objective: To evaluate longitudinal associations of distress and inflammation with somatic and depressive symptom severity in breast cancer patients, from before to six months after neoadjuvant chemotherapy. We also explored feasibility and effects o
Externí odkaz:
https://doaj.org/article/00e5c5eafb8a4705bfbe021b9dc80d4c
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151890 (2016)
RATIONALE:Chemotherapy-induced cognitive impairment, also known as 'chemobrain', is now widely recognized as a frequent adverse side effect of cancer treatment that often persists into survivorship. There are no drugs available to prevent or treat ch
Externí odkaz:
https://doaj.org/article/dab507aed30d4b94b99d70a7b0928dc4
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background Hypoxic-Ischemic Encephalopathy (HIE) is a leading cause of mortality and morbidity in newborns. Recent research has shown promise in using intranasal mesenchymal stem cell (MSC) therapy if administered within 10 days after Hypoxi
Externí odkaz:
https://doaj.org/article/06a0f66582084776be8f07ce80393505
Autor:
Elisabeth G Vichaya, Gabriel S Chiu, Karen eKrukowski, Tamara E Lacourt, Annemieke eKavelaars, Robert eDantzer, Cobi J Heijnen, Adam K Walker
Publikováno v:
Frontiers in Neuroscience, Vol 9 (2015)
While chemotherapeutic agents have yielded relative success in the treatment of cancer, patients are often plagued with unwanted and even debilitating side-effects from the treatment which can lead to dose reduction or even cessation of treatment. Co
Externí odkaz:
https://doaj.org/article/1766d89e11e3407d9188fabb10d831fc
Autor:
Elke Kooijman, Cora H Nijboer, Cindy T J van Velthoven, Wouter Mol, Rick M Dijkhuizen, Jozef Kesecioglu, Cobi J Heijnen
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e90584 (2014)
Subarachnoid hemorrhage (SAH) represents a considerable health problem with an incidence of 6-7 per 100.000 individuals per year in Western society. We investigated the long-term consequences of SAH on behavior, neuroinflammation and gray- and white-
Externí odkaz:
https://doaj.org/article/e09f355636c143f6a8810e974396ad3f
Autor:
Vanessa Donega, Cora H Nijboer, Luca Braccioli, Ineke Slaper-Cortenbach, Annemieke Kavelaars, Frank van Bel, Cobi J Heijnen
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112339 (2014)
Intranasal treatment with C57BL/6 MSCs reduces lesion volume and improves motor and cognitive behavior in the neonatal hypoxic-ischemic (HI) mouse model. In this study, we investigated the potential of human MSCs (hMSCs) to treat HI brain injury in t
Externí odkaz:
https://doaj.org/article/2239a1ddfac44ca499d8f8f9635e10e1
Autor:
Qi-Liang Mao-Ying, Annemieke Kavelaars, Karen Krukowski, Xiao-Jiao Huo, Wenjun Zhou, Theodore J Price, Charles Cleeland, Cobi J Heijnen
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100701 (2014)
Chemotherapy-induced peripheral neuropathy (CIPN) characterized by loss of sensory sensitivity and pain in hands and feet is the major dose-limiting toxicity of many chemotherapeutics. At present, there are no FDA-approved treatments for CIPN. The an
Externí odkaz:
https://doaj.org/article/44e74bf2bc20480e95f8aa91a8084fec