Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Cobi J, Heijnen"'
Autor:
Vincent D. Lai, Jensine Paoletti-Hatcher, E. Lydia Wu-Chung, Itee Mahant, Daniel L. Argueta, Kelly N. Brice, Bryan T. Denny, Charles Green, Luis D. Medina, Paul E. Schulz, Jennifer M. Stinson, Cobi J. Heijnen, Christopher P. Fagundes
Publikováno v:
Comprehensive Psychoneuroendocrinology, Vol 20, Iss , Pp 100271- (2024)
Caregivers for spouses with Alzheimer's disease and related dementias (ADRD) experience drastic changes in the marital relationship that may put them at risk for worsening well-being. Perceived partner responsiveness, or feeling cared for, understood
Externí odkaz:
https://doaj.org/article/564cfbb0c1a147eeb19aca2953cc04ba
Publikováno v:
Comprehensive Psychoneuroendocrinology, Vol 20, Iss , Pp 100269- (2024)
Objective: To evaluate longitudinal associations of distress and inflammation with somatic and depressive symptom severity in breast cancer patients, from before to six months after neoadjuvant chemotherapy. We also explored feasibility and effects o
Externí odkaz:
https://doaj.org/article/00e5c5eafb8a4705bfbe021b9dc80d4c
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background Hypoxic-Ischemic Encephalopathy (HIE) is a leading cause of mortality and morbidity in newborns. Recent research has shown promise in using intranasal mesenchymal stem cell (MSC) therapy if administered within 10 days after Hypoxi
Externí odkaz:
https://doaj.org/article/06a0f66582084776be8f07ce80393505
Autor:
Miriam Zamorano, Jenolyn F. Alexander, Desiree Catania, Shruti Dharmaraj, Annemieke Kavelaars, Cobi J. Heijnen
Publikováno v:
Immunity & Ageing, Vol 20, Iss 1, Pp 1-18 (2023)
Highlights • Cisplatin accelerates formation of tau deposits in entorhinal cortex and hippocampus of older female and male mice. • Nasal administration of MSC after cisplatin prevents formation of tau deposits in the brain. • Tau deposits are a
Externí odkaz:
https://doaj.org/article/fefcbd1c7c8f45ca871d07b0cc6694ed
Autor:
Anand Kumar Singh, Rajasekaran Mahalingam, Silvia Squillace, Kenneth A. Jacobson, Dilip K. Tosh, Shruti Dharmaraj, Susan A. Farr, Annemieke Kavelaars, Daniela Salvemini, Cobi J. Heijnen
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract Cisplatin is used to combat solid tumors. However, patients treated with cisplatin often develop cognitive impairments, sensorimotor deficits, and peripheral neuropathy. There is no FDA-approved treatment for these neurotoxicities. We invest
Externí odkaz:
https://doaj.org/article/5b44d6910ee840eebed105fd78d879a2
Autor:
Angie C. A. Chiang, Alexandre V. Seua, Pooja Singhmar, Luis D. Arroyo, Rajasekaran Mahalingam, Jian Hu, Annemieke Kavelaars, Cobi J. Heijnen
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-15 (2020)
Abstract Frequently reported neurotoxic sequelae of cancer treatment include cognitive deficits and sensorimotor abnormalities that have long-lasting negative effects on the quality of life of an increasing number of cancer survivors. The underlying
Externí odkaz:
https://doaj.org/article/033168cd016a49eb8c3097d800f1b85f
Autor:
Krystal English, Andrew Shepherd, Ndidi-Ese Uzor, Ronnie Trinh, Annemieke Kavelaars, Cobi J. Heijnen
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-14 (2020)
Abstract Neurodegenerative disorders, including chemotherapy-induced cognitive impairment, are associated with neuronal mitochondrial dysfunction. Cisplatin, a commonly used chemotherapeutic, induces neuronal mitochondrial dysfunction in vivo and in
Externí odkaz:
https://doaj.org/article/25ca49647ebc4517838833a5d4c7449b
Autor:
Susmita K. Singh, Karen Krukowski, Geoffroy O. Laumet, Drew Weis, Jenolyn F. Alexander, Cobi J. Heijnen, Annemieke Kavelaars
Publikováno v:
JCI Insight, Vol 7, Iss 5 (2022)
Understanding the endogenous mechanisms regulating resolution of pain may identify novel targets for treatment of chronic pain. Resolution of chemotherapy-induced peripheral neuropathy (CIPN) after treatment completion depends on CD8+ T cells and on
Externí odkaz:
https://doaj.org/article/b4b6582800e64046b270994c31a1808b
Autor:
Julie G. Walker, Terri S. Armstrong, Barbara J. O'Brien, Mark R. Gilbert, Rebecca L. Casarez, Christopher Fagundes, Cobi J. Heijnen, Clark R. Andersen, Ying Yuan, Jimin Wu, Geri LoBiondo-Wood
Publikováno v:
Comprehensive Psychoneuroendocrinology, Vol 8, Iss , Pp 100099- (2021)
Background: Leptomeningeal metastasis (LM) creates symptoms related to both the disease within the nervous system and treatment toxicities. Biologic processes, such as inflammation and behavioral processes, such as the meaning ascribed to illness (Me
Externí odkaz:
https://doaj.org/article/05f08b960ffd481185a8febca67c387b
Autor:
E. Lydia Wu, Ryan L. Brown, Diana A. Chirinos, Michelle A. Chen, Marcel A. de Dios, Daniela M. Taylor, Jonathan E. Butner, Cobi J. Heijnen, Christopher P. Fagundes
Publikováno v:
Comprehensive Psychoneuroendocrinology, Vol 7, Iss , Pp 100056- (2021)
Widow(er)s experience significant sleep disruption that may dysregulate immune functioning. This longitudinal study aimed to determine 1) whether changes in sleep quality were associated with changes in pro-inflammatory cytokine production during the
Externí odkaz:
https://doaj.org/article/475b99d8245a46f6b3a51fa62b980cd4