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Autor:
Yu, Dahyun, Zarate, Nicole, White, Angel, Coates, De’jah, Tsai, Wei, Nanclares, Carmen, Cuccu, Francesco, Yue, Johnny S., Brown, Taylor G., Mansky, Rachel H., Jiang, Kevin, Kim, Hyuck, Nichols-Meade, Tessa, Larson, Sarah N., Gundry, Katherine, Zhang, Ying, Tomas-Zapico, Cristina, Lucas, Jose J., Benneyworth, Michael, Öz, Gülin, Cvetanovic, Marija, Araque, Alfonso, Gomez-Pastor, Rocio
Additional file 3. Genetic deletion of CK2α’ does not ameliorate anxiety-like behaviors or locomotor asymmetry of zQ175 HD at 12 months of age. a-e, Gross motor performance, exploratory behavior, and anxiety-like behavior were assessed during 30 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33fce9ce9ef81f0fd4236b83799ee38d
Autor:
Yu, Dahyun, Zarate, Nicole, White, Angel, Coates, De’jah, Tsai, Wei, Nanclares, Carmen, Cuccu, Francesco, Yue, Johnny S., Brown, Taylor G., Mansky, Rachel H., Jiang, Kevin, Kim, Hyuck, Nichols-Meade, Tessa, Larson, Sarah N., Gundry, Katherine, Zhang, Ying, Tomas-Zapico, Cristina, Lucas, Jose J., Benneyworth, Michael, Öz, Gülin, Cvetanovic, Marija, Araque, Alfonso, Gomez-Pastor, Rocio
Additional file 6. WGCNA modules genes assignment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680acd7859e218200a08222d34e72bf0
Autor:
Yu, Dahyun, Zarate, Nicole, White, Angel, Coates, De’jah, Tsai, Wei, Nanclares, Carmen, Cuccu, Francesco, Yue, Johnny S., Brown, Taylor G., Mansky, Rachel H., Jiang, Kevin, Kim, Hyuck, Nichols-Meade, Tessa, Larson, Sarah N., Gundry, Katherine, Zhang, Ying, Tomas-Zapico, Cristina, Lucas, Jose J., Benneyworth, Michael, Öz, Gülin, Cvetanovic, Marija, Araque, Alfonso, Gomez-Pastor, Rocio
Additional file 15. SNCA regulates the expression of synaptic genes identified in IPA analysis in R6/1 mice. a, IB for α-syn (4D6 antibody) and mtHTT (EM48 antibody) in the striatum of 5 months old WT, SNCAKO, R6/1 and R6/1:SNCAKO (n=3 mice/genotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9505a5daf607a572c229274c6fb5c8b8
Autor:
Yu, Dahyun, Zarate, Nicole, White, Angel, Coates, De’jah, Tsai, Wei, Nanclares, Carmen, Cuccu, Francesco, Yue, Johnny S., Brown, Taylor G., Mansky, Rachel H., Jiang, Kevin, Kim, Hyuck, Nichols-Meade, Tessa, Larson, Sarah N., Gundry, Katherine, Zhang, Ying, Tomas-Zapico, Cristina, Lucas, Jose J., Benneyworth, Michael, Öz, Gülin, Cvetanovic, Marija, Araque, Alfonso, Gomez-Pastor, Rocio
Additional file 5. Expressions of all identified co-expression gene modules from WGCNA studies for each mouse sample. A total of 20 different modules were identified when comparing all the genotypes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58cbf808dbe65707da2ce7fb52a7bedd
Autor:
Yu, Dahyun, Zarate, Nicole, White, Angel, Coates, De’jah, Tsai, Wei, Nanclares, Carmen, Cuccu, Francesco, Yue, Johnny S., Brown, Taylor G., Mansky, Rachel H., Jiang, Kevin, Kim, Hyuck, Nichols-Meade, Tessa, Larson, Sarah N., Gundry, Katherine, Zhang, Ying, Tomas-Zapico, Cristina, Lucas, Jose J., Benneyworth, Michael, Öz, Gülin, Cvetanovic, Marija, Araque, Alfonso, Gomez-Pastor, Rocio
Additional file 2. Deficiency in CK2α’ expression does not affect MSN abundance but does influence synaptic genes. a, b, Representative images show the labeling of Ctip2 (a) and quantitative analysis (b) from striatum of zQ175 and zQ175:CK2α’(+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6394d5442f596ebe77bc0a5ce2a2a18f
Autor:
Yu, Dahyun, Zarate, Nicole, White, Angel, Coates, De’jah, Tsai, Wei, Nanclares, Carmen, Cuccu, Francesco, Yue, Johnny S., Brown, Taylor G., Mansky, Rachel H., Jiang, Kevin, Kim, Hyuck, Nichols-Meade, Tessa, Larson, Sarah N., Gundry, Katherine, Zhang, Ying, Tomas-Zapico, Cristina, Lucas, Jose J., Benneyworth, Michael, Öz, Gülin, Cvetanovic, Marija, Araque, Alfonso, Gomez-Pastor, Rocio
Additional file 7. WGCNA module names and number of genes per module.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d1592d956b298842171705cad26ae3
Autor:
Yu, Dahyun, Zarate, Nicole, White, Angel, Coates, De’jah, Tsai, Wei, Nanclares, Carmen, Cuccu, Francesco, Yue, Johnny S., Brown, Taylor G., Mansky, Rachel H., Jiang, Kevin, Kim, Hyuck, Nichols-Meade, Tessa, Larson, Sarah N., Gundry, Katherine, Zhang, Ying, Tomas-Zapico, Cristina, Lucas, Jose J., Benneyworth, Michael, Öz, Gülin, Cvetanovic, Marija, Araque, Alfonso, Gomez-Pastor, Rocio
Additional file 4. CK2α’ does not alter cognitive behavior in symptomatic HD mice. a, b, Freezing time in the cued (a) and contextual fear conditioning test (b). c-e, Performance on the Barnes maze (BM) task measured by latency to reach the escape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f8a65255e46b8aa439846db10cf3ea
Autor:
Yu, Dahyun, Zarate, Nicole, White, Angel, Coates, De’jah, Tsai, Wei, Nanclares, Carmen, Cuccu, Francesco, Yue, Johnny S., Brown, Taylor G., Mansky, Rachel H., Jiang, Kevin, Kim, Hyuck, Nichols-Meade, Tessa, Larson, Sarah N., Gundry, Katherine, Zhang, Ying, Tomas-Zapico, Cristina, Lucas, Jose J., Benneyworth, Michael, Öz, Gülin, Cvetanovic, Marija, Araque, Alfonso, Gomez-Pastor, Rocio
Additional file 8. RNA-Seq comparison between samples and with Langfelder et al., 2016 [49]. a, Kruskal-Wallis test of module expressions between zQ175 mice and WT mice. b IPA canonical pathway analysis of module genes for module “Red”. c, Cook
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dedf362fc3428bae31b05a625898d90
Autor:
Yu, Dahyun, Zarate, Nicole, White, Angel, Coates, De'jah, Tsai, Wei, Nanclares, Carmen, Cuccu, Francesco, Yue, Johnny S., Brown, Taylor G., Mansky, Rachel H., Jiang, Kevin, Kim, Hyuck, Nichols‑Meade, Tessa, Larson, Sarah N., Gundry, Katherine, Zhang, Ying, Tomas‑Zapico, Cristina, Lucas, Jose J., Benneyworth, Michael, Öz, Gülin
Publikováno v:
Acta Neuropathologica Communications; 6/22/2022, Vol. 10 Issue 1, p1-1, 1p