Zobrazeno 1 - 10
of 60
pro vyhledávání: '"CoAlation"'
Autor:
Oksana Malanchuk, Anna Bdzhola, Sergii Palchevskyi, Volodymyr Bdzhola, Peng Chai, Olivier E. Pardo, Michael J. Seckl, Adrija Banerjee, Sew Yeu Peak-Chew, Mark Skehel, Lalitha Guruprasad, Alexander Zhyvoloup, Ivan Gout, Valeriy Filonenko
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8747 (2024)
Ribosomal protein S6 kinases belong to a family of highly conserved enzymes in eukaryotes that regulate cell growth, proliferation, survival, and the stress response. It is well established that the activation and downstream signalling of p70S6Ks inv
Externí odkaz:
https://doaj.org/article/ecc17b2cb472444d9e11f6c91779a085
Akademický článek
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Autor:
Valeriy Filonenko, Ivan Gout
Publikováno v:
BBA Advances, Vol 3, Iss , Pp 100075- (2023)
Coenzyme A (CoA) is an essential cofactor in all living cells which plays critical role in cellular metabolism, the regulation of gene expression and the biosynthesis of major cellular constituents. Recently, CoA was found to function as a major anti
Externí odkaz:
https://doaj.org/article/b6ad99d42659477598d1cdcf8af2f948
Autor:
Maria-Armineh Tossounian, Stefan Denchev Hristov, Jonathan Alexis Semelak, Bess Yi Kun Yu, Maria Baczynska, Yuhan Zhao, Dario Ariel Estrin, Madia Trujillo, Valeriy Filonenko, Jerome Gouge, Ivan Gout
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9359 (2023)
Coenzyme A (CoA) is a key cellular metabolite which participates in diverse metabolic pathways, regulation of gene expression and the antioxidant defense mechanism. Human NME1 (hNME1), which is a moonlighting protein, was identified as a major CoA-bi
Externí odkaz:
https://doaj.org/article/b4c9ae7e5f1a4bca88b41ae1c09621a0
Autor:
Maria-Armineh Tossounian, Maria Baczynska, William Dalton, Sew Yeu Peak-Chew, Kipras Undzenas, George Korza, Valeriy Filonenko, Mark Skehel, Peter Setlow, Ivan Gout
Publikováno v:
Antioxidants, Vol 12, Iss 4, p 938 (2023)
Coenzyme A (CoA) is an important cellular metabolite that is critical for metabolic processes and the regulation of gene expression. Recent discovery of the antioxidant function of CoA has highlighted its protective role that leads to the formation o
Externí odkaz:
https://doaj.org/article/be5094fcf3b64f328a67a25706309bd5
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Tammaryn Lashley, Maria-Armineh Tossounian, Neve Costello Heaven, Samantha Wallworth, Sew Peak-Chew, Aaron Bradshaw, J. Mark Cooper, Rohan de Silva, Surjit Kaila Srai, Oksana Malanchuk, Valeriy Filonenko, Margreet B. Koopman, Stefan G. D. Rüdiger, Mark Skehel, Ivan Gout
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Alzheimer’s disease (AD) is a neurodegenerative disorder, accounting for at least two-thirds of dementia cases. A combination of genetic, epigenetic and environmental triggers is widely accepted to be responsible for the onset and development of AD
Externí odkaz:
https://doaj.org/article/b23506173cea4a9a8b88bed62e3c2af3
Autor:
Bess Yi Kun Yu, Maria-Armineh Tossounian, Stefan Denchev Hristov, Ryan Lawrence, Pallavi Arora, Yugo Tsuchiya, Sew Yeu Peak-Chew, Valeriy Filonenko, Sally Oxenford, Richard Angell, Jerome Gouge, Mark Skehel, Ivan Gout
Publikováno v:
Redox Biology, Vol 44, Iss , Pp 101978- (2021)
The metastasis suppressor protein NME1 is an evolutionarily conserved and multifunctional enzyme that plays an important role in suppressing the invasion and metastasis of tumour cells. The nucleoside diphosphate kinase (NDPK) activity of NME1 is wel
Externí odkaz:
https://doaj.org/article/1a888cb0c73e41febf4761fac8db29c6
Autor:
Maria-Armineh Tossounian, Maria Baczynska, William Dalton, Charlie Newell, Yilin Ma, Sayoni Das, Jonathan Alexis Semelak, Dario Ariel Estrin, Valeriy Filonenko, Madia Trujillo, Sew Yeu Peak-Chew, Mark Skehel, Franca Fraternali, Christine Orengo, Ivan Gout
Publikováno v:
Antioxidants, Vol 11, Iss 7, p 1362 (2022)
Coenzyme A (CoA) is a key cellular metabolite known for its diverse functions in metabolism and regulation of gene expression. CoA was recently shown to play an important antioxidant role under various cellular stress conditions by forming a disulfid
Externí odkaz:
https://doaj.org/article/56baf0cbdafb4d66a66c780f7cee1d2d