Citrate-Mediated Acyl-CoA Synthesis Is Required for the Promotion of Growth and Triacylglycerol Production in Oleaginous Yeast Lipomyces starkeyi

Autor: Rikako Sato, Satoshi Ara, Harutake Yamazaki, Koji Ishiya, Sachiyo Aburatani, Hiroaki Takaku

Publikováno v: Microorganisms, Vol 9, Iss 8, p 1693 (2021)

The oleaginous yeast Lipomyces starkeyi is an excellent producer of triacylglycerol (TAG) as a feedstock for biodiesel production. To understand the regulation of TAG synthesis, we attempted to isolate mutants with decreased lipid productivity and an

Externí odkaz: https://doaj.org/article/52e339e080b746b69a079fd923cb1923

Inactivation of Target RNA Cleavage of a III-B CRISPR-Cas System Induces Robust Autoimmunity in Saccharolobus islandicus

Autor: Yan Zhang, Jinzhong Lin, Xuhui Tian, Yuan Wang, Ruiliang Zhao, Chenwei Wu, Xiaoning Wang, Pengpeng Zhao, Xiaonan Bi, Zhenxiao Yu, Wenyuan Han, Nan Peng, Yun Xiang Liang, Qunxin She

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 15; Pages: 8515
Zhang, Y, Lin, J, Tian, X, Wang, Y, Zhao, R, Wu, C, Wang, X, Zhao, P, Bi, X, Yu, Z, Han, W, Peng, N, Liang, Y X & She, Q 2022, ' Inactivation of Target RNA Cleavage of a III-B CRISPR-Cas System Induces Robust Autoimmunity in Saccharolobus islandicus ', International Journal of Molecular Sciences, vol. 23, no. 15, 8515 . https://doi.org/10.3390/ijms23158515

Type III CRISPR-Cas systems show the target (tg)RNA-activated indiscriminate DNA cleavage and synthesis of oligoadenylates (cOA) and a secondary signal that activates downstream nuclease effectors to exert indiscriminate RNA/DNA cleavage, and both ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20713f764e3c2067db1b01d44fbafcb7

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Mitochondrial fatty acids and neurodegenerative disorders

Autor: Kastaniotis, A. J. (Alexander J.), Autio, K. J. (Kaija J.), Nair, R. R. (Remya R.)

Fatty acids in mitochondria, in sensu stricto, arise either as β-oxidation substrates imported via the carnitine shuttle or through de novo synthesis by the mitochondrial fatty acid synthesis (mtFAS) pathway. Defects in mtFAS or processes involved i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2423::a318df70c3608a41024ed5cbdf62d2ac
http://urn.fi/urn:nbn:fi-fe202103086736