Zobrazeno 1 - 10
of 1 347
pro vyhledávání: '"Co-receptor"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Expressed on the surface of CD8+ T cells, the CD8 co-receptor is a key component of the T cells that contributes to antigen recognition, immune cell maturation, and immune cell signaling. While CD8 is widely recognized as a co-stimulatory molecule fo
Externí odkaz:
https://doaj.org/article/b90a01080bd544ea9ff2c1bcb3f30d63
Autor:
Akiko Hashimoto-Tane, Edward P. Bowman, Machie Sakuma, Natsumi Yoneda, Katsuyuki Yugi, Rene de Waal Malefyt, Takashi Saito
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Lymphocyte activation gene (Lag)-3 is an inhibitory co-receptor and target of immune checkpoint inhibitor (ICI) therapy for cancer. The dynamic behavior of Lag-3 was analyzed at the immune synapse upon T-cell activation to elucidate the Lag-3 inhibit
Externí odkaz:
https://doaj.org/article/01488bb5ac8c4a6ab38ab7b584d9ff15
Autor:
Ling Yue, Rui Xu, Samantha Mclnally, Qianhong Qin, Jake W. Rhodes, Erick Muok, Gisele Umviligihozo, Kelsie Brooks, Jiayi Zhang, Zhaohui Qin, Jean Bizimana, Jonathan Hare, Matthew A. Price, Susan A. Allen, Etienne Karita, Eric Hunter
Publikováno v:
Viruses, Vol 16, Iss 11, p 1706 (2024)
HIV-1 subtypes have distinct geographical distributions, with subtypes A, C, and D and inter-subtype recombinants circulating in sub-Saharan Africa. Historically, individuals living with subtype A viruses exhibit slower CD4 decline and progression to
Externí odkaz:
https://doaj.org/article/e08124aee663449db461dbfda7e63337
Autor:
Kang Li, Huanhuan Chen, Jianjun Li, Yi Feng, Shujia Liang, Abdur Rashid, Meiliang Liu, Sisi Li, Qingfei Chu, Yuhua Ruan, Hui Xing, Guanghua Lan, Wentao Qiao, Yiming Shao
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT CRF01_AE strains have been shown to form multiple transmission clusters in China, and some clusters have disparate pathogenicity in Chinese men who have sex with men. This study focused on other CRF01_AE clusters prevalent in heterosexual po
Externí odkaz:
https://doaj.org/article/eb4972874f774c938353595c426b9bae
Autor:
Daisy Ko, Sherry McLaughlin, Wenjie Deng, James I. Mullins, Joan Dragavon, Socorro Harb, Robert W. Coombs, Lisa M. Frenkel
Publikováno v:
Viruses, Vol 16, Iss 4, p 510 (2024)
HIV-1 typically infects cells via the CD4 receptor and CCR5 or CXCR4 co-receptors. Maraviroc is a CCR5-specific viral entry inhibitor; knowledge of viral co-receptor specificity is important prior to usage. We developed and validated an economical V3
Externí odkaz:
https://doaj.org/article/f23c85245d7049c8b39453509c2488f3
Autor:
Heather E. Grant, Sunando Roy, Rachel Williams, Helena Tutill, Bridget Ferns, Patricia A. Cane, J. Wilson Carswell, Deogratius Ssemwanga, Pontiano Kaleebu, Judith Breuer, Andrew J. Leigh Brown
Publikováno v:
Retrovirology, Vol 19, Iss 1, Pp 1-10 (2022)
Abstract We present 109 near full-length HIV genomes amplified from blood serum samples obtained during early 1986 from across Uganda, which to our knowledge is the earliest and largest population sample from the initial phase of the HIV epidemic in
Externí odkaz:
https://doaj.org/article/b9ce012fa63f4886844455303bb654f5
Autor:
Yu. V. Ostankova, V. S. Davydenko, A. N. Shchemelev, E. B. Zueva, P. A. Virolainen, Areg A. Totolyan
Publikováno v:
Проблемы особо опасных инфекций, Vol 0, Iss 3, Pp 120-128 (2022)
The aim of the study was to determine the tropism of the human immunodeficiency virus in patients with virological failure of antiretroviral therapy (ART) from the Arkhangelsk Region based on the analysis of the env gene V3 loop nucleotide sequence.M
Externí odkaz:
https://doaj.org/article/f3daa5b0ad9c444c8ba9fba0dfb0d922
Akademický článek
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Akademický článek
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Autor:
Xiao-Bin Fan, Bao-Tong Mo, Guo-Cheng Li, Ling-Qiao Huang, Hao Guo, Xin-Lin Gong, Chen-Zhu Wang
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background Odorant receptors (ORs) as odorant-gated ion channels play a crucial role in insect olfaction. They are formed by a heteromultimeric complex of the odorant receptor co-receptor (Orco) and a ligand-selective Or. Other types of olfa
Externí odkaz:
https://doaj.org/article/1f06c9e60025499eac4517e630e95516