Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Co-inhibitory Molecules"'
Publikováno v:
International Journal of General Medicine, Vol Volume 17, Pp 651-661 (2024)
Meiju Deng,1,2,* Yongqin Zeng,2,3,* Ying Liu,2 Xiaolei Wang,1,2 Na Chen,1,2 Mengyuan Zhang,1,4– 6 Meiqing Jiang,1,4– 6 Hongxin Zhao,2 Juan Du1,4– 6 1Beijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Disease
Externí odkaz:
https://doaj.org/article/f08be967f1e6474baf1bdbd4407b9ba7
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 964 (2024)
Hepatitis B, caused by the hepatitis B virus (HBV), often progresses to chronic infection, leading to severe complications, such as cirrhosis, liver failure, and hepatocellular carcinoma. Chronic HBV infection is characterized by a complex interplay
Externí odkaz:
https://doaj.org/article/2b5df8bbc5e84b79aeb43c5359412c76
Autor:
Fatemah S. Basingab, Reem A. Alzahrani, Aisha A. Alrofaidi, Ahmed S. Barefah, Rawan M. Hammad, Hadil M. Alahdal, Jehan S. Alrahimi, Kawther A. Zaher, Ali H. Algiraigri, Mai M. El-Daly, Saleh A. Alkarim, Alia M. Aldahlawi
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 523 (2024)
Herpesvirus entry mediator (HVEM) is a molecular switch that can modulate immune responses against cancer. The significance of HVEM as an immune checkpoint target and a potential prognostic biomarker in malignancies is still controversial. This study
Externí odkaz:
https://doaj.org/article/559e2bc2102942889e110d4e0060db11
Autor:
Qiaohong Geng, Peifu Jiao
Publikováno v:
Molecules, Vol 29, Iss 2, p 454 (2024)
Targeting PD-L1 via monospecific antibodies has shown durable clinical benefits and long-term remissions where patients exhibit no clinical cancer signs for many years after treatment. However, the durable clinical benefits and long-term remissions b
Externí odkaz:
https://doaj.org/article/07ab49a7fbab4a5f8776ac178822811e
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The use of immune checkpoint inhibitors (ICIs) targeting the T cell inhibitory pathways has revolutionized cancer treatment. However, ICIs might induce progressive atopic dermatitis (AD) by affecting T cell reactivation. The critical role of T cells
Externí odkaz:
https://doaj.org/article/e1a504a6a03447a09e701cb4fecff251
Akademický článek
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Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Activated cytotoxic CD8+ T cells can selectively kill target cells in an antigen-specific manner. However, their prolonged activation often has detrimental effects on tissue homeostasis and function. Indeed, overwhelming cytotoxic activity of CD8+ T
Externí odkaz:
https://doaj.org/article/2e41220289da4506ad9b2c179f2fc53f
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Psoriasis is a chronic, systemic immune-mediated inflammatory disease manifesting in the skin, joint or both. Co-signaling molecules are essential for determining the magnitude of the T cell response to the antigen. According to the function of co-si
Externí odkaz:
https://doaj.org/article/10118c36ca654af787bc1d62db3cb5ae
Publikováno v:
Viruses, Vol 13, Iss 12, p 2358 (2021)
Foot-and-mouth disease (FMD) is characterized by a pronounced lymphopenia that is associated with immune suppression. However, the mechanisms leading to lymphopenia remain unclear. In this study, the number of total CD4+, CD8+ T cells, B cells, and N
Externí odkaz:
https://doaj.org/article/ec30827a3ed648e7a14a9a35d29b6591
Publikováno v:
Chinese Medical Journal, Vol 130, Iss 10, Pp 1249-1252 (2017)
Externí odkaz:
https://doaj.org/article/8593715457824c3a907a67759087f914