Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Co-culture models"'
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Tumor organoids, especially patient-derived organoids (PDOs) exhibit marked similarities in histopathological morphology, genomic alterations, and specific marker expression profiles to those of primary tumour tissues. They are applied in va
Externí odkaz:
https://doaj.org/article/08eccc812de0434c964aa529148a4c9c
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract IPF is a fatal lung disease characterized by intensive remodeling of lung tissue leading to respiratory failure. The remodeling in IPF lungs is largely characterized by uncontrolled fibrosis. Fibroblasts and their contractile phenotype the m
Externí odkaz:
https://doaj.org/article/123a0de2908b475bb6ca6238b059800a
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
The antibacterial biofunctionality of bone implants is essential for the prevention and treatment of implant-associated infections (IAI). In vitro co-culture models are utilized to assess this and study bacteria-host cell interactions at the implant
Externí odkaz:
https://doaj.org/article/999a68fa9acc4883af3dc722791d350f
Co-Culture Models: Key Players in In Vitro Neurotoxicity, Neurodegeneration and BBB Modeling Studies
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 626 (2024)
The biological barriers existing in the human body separate the blood circulation from the interstitial fluid in tissues. The blood–brain barrier (BBB) isolates the central nervous system from the bloodstream, presenting a dual role: the protection
Externí odkaz:
https://doaj.org/article/4fe14172889746528bf373d6ab0c97ee
Autor:
Sebastian Buchmann, Alessandro Enrico, Muriel Alexandra Holzreuter, Michael Reid, Erica Zeglio, Frank Niklaus, Göran Stemme, Anna Herland
Publikováno v:
Materials Today Bio, Vol 21, Iss , Pp 100706- (2023)
To model complex biological tissue in vitro, a specific layout for the position and numbers of each cell type is necessary. Establishing such a layout requires manual cell placement in three dimensions (3D) with micrometric precision, which is compli
Externí odkaz:
https://doaj.org/article/81b72763b0494c258054c2424f1a7b96
Autor:
F. Thiam, S. Al Yazeedi, K. Feng, S. Phogat, E. Demirsoy, J. Brussow, F. A. Abokor, E. T. Osei
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Asthma is a chronic lung disease involving airway inflammation and fibrosis. Fibroblasts are the main effector cells important for lung tissue production which becomes abnormal in asthmatics and is one of the main contributors to airway fibrosis. Alt
Externí odkaz:
https://doaj.org/article/74ee47f666ec4b7bb598e6eecf06daee
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Three-dimensional cancer organoids derived from self-organizing cancer stems are ex vivo miniatures of tumors that faithfully recapitulate their structure, distinctive cancer features, and genetic signatures. As novel tools, current cancer organoids
Externí odkaz:
https://doaj.org/article/194e43bf18f44fe48ff2f38154b2bc9f
Autor:
Katrin Agnes Muenzebrock, Valerie Kersten, Jacqueline Alblas, Joao Pedro Garcia, Laura B. Creemers
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Osteoarthritis (OA) is a highly prevalent disease and a major health burden. Its development and progression are influenced by factors such as age, obesity or joint overuse. As a whole organ disease OA affects not only cartilage, bone and synovium bu
Externí odkaz:
https://doaj.org/article/32b19c8ed35442aaa159e6ffe3dd73b6
Publikováno v:
Advanced NanoBiomed Research, Vol 1, Iss 6, Pp n/a-n/a (2021)
Air−liquid interface (ALI) culture models currently represent a valid instrument to recreate the typical aspects of the respiratory tract in vitro in both healthy and diseased state. They can help reducing the number of animal experiments, and henc
Externí odkaz:
https://doaj.org/article/0b6549e66c4041b5bc5fdfe5bb205ef0
Publikováno v:
Journal of Functional Foods, Vol 52, Iss , Pp 603-610 (2019)
Ultraviolet radiation induces skin damage, inflammation, and aging. To explore the protective effects of blueberry extract (BE) against ultraviolet-C (UV-C) radiation, we analysed human skin keratinocyte (HaCaT) and human foreskin fibroblast (HFF) ce
Externí odkaz:
https://doaj.org/article/52424ab665244b41bd5b6312b511564b