Molecular markers for cervical cancer screening

Autor: Coşkun Güzel, Jenny van Sten-Van't Hoff, Inge M C M de Kok, Theo M Luider, Natalia Govorukhina, Alexander Boychenko, Rainer Bischoff

Publikováno v: Expert review of proteomics, 18(8), 675-691. Taylor & Francis Ltd

This review gives an overview of current screening practices for cervical cancer. In the introduction, we will cover approaches of population screening focusing on high-risk Human Papilloma Virus (hrHPV) and the need for a better triage assay. We wil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911ef963bad86fc73462cd9acd7422b1
https://doi.org/10.1080/14789450.2021.1980387

Alteration of protein expression and spliceosome pathway activity during Barrett's carcinogenesis

Autor: Angela Bureo Gonzalez, Coşkun Güzel, Michail Doukas, Christoph Stingl, Gerben E. Breimer, Sybren L. Meijer, Jacques J.G.H.M. Bergman, Kai Yi N. Phoa, Theo M. Luider

Publikováno v: Journal of Gastroenterology
Journal of gastroenterology, 56(9), 791-807. Springer Japan
Journal of Gastroenterology, 56(9), 791-807. Springer Japan

Background Barrett’s esophagus (BE) is a known precursor lesion and the strongest risk factor for esophageal adenocarcinoma (EAC), a common and lethal type of cancer. Prediction of risk, the basis for efficient intervention, is commonly solely base

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d4589c2fdee697880e8c5a7dc67cae4
https://pubmed.ncbi.nlm.nih.gov/34227026

Quantification of Calcyclin and Heat Shock Protein 90 in Sera from Women with and without Preeclampsia by Mass Spectrometry

Autor: Eric A.P. Steegers, Marcel van der Weiden, Christoph Stingl, Thierry P P van den Bosch, Theo M. Luider, Caroline B van den Berg, Coşkun Güzel, Johannes J. Duvekot, Régine P.M. Steegers-Theunissen

Publikováno v: Proteomics. Clinical Applications
Proteomics Clinical Applications, 13(3):1800181. Wiley-VCH

Purpose: The objective of present study is to determine serum levels and placental distribution of two interacting proteins calcyclin and heat shock protein 90 in preeclampsia. Experimental design: Maternal serum levels of calcyclin and heat shock pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f4168f79c9461123e2ffa6e34962a4
https://doi.org/10.1002/prca.201800181

Comparison of Targeted Mass Spectrometry Techniques with an Immunoassay: A Case Study for HSP90α

Autor: Theo M Luidert, Lennard J. M. Dekker, Coşkun Güzel, Rainer Bischoff, Alexander P. Boichenko, Ate G.J. van der Zee, Natalia Govorukhina, Christoph Stingl

Publikováno v: Proteomics. Clinical Applications, 12(1):1700107. WILEY-V C H VERLAG GMBH
Proteomics Clinical Applications, 12(1):1700107. Wiley-VCH

PURPOSE: The objective of this study was to better understand factors governing the variability and sensitivity in SRM and PRM, compared to immunoassay.EXPERIMENTAL DESIGN: A 2D-LC-MS/MS-based SRM and PRM assay was developed for quantitative measurem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec6c2bf64170bded97a2032703155a9
https://pubmed.ncbi.nlm.nih.gov/28975736

Elevated levels of protein AMBP in cerebrospinal fluid of women with preeclampsia compared to normotensive pregnant women

Autor: Stefan R. Hansson, Caroline B. van den Berg, Eric A.P. Steegers, Johannes Versendaal, Coşkun Güzel, Marcel P. Stoop, Johannes J. Duvekot, Thomas G. de Leeuw, Theo M. Luider

Publikováno v: Proteomics Clinical Applications, 11(1-2):1600082. Wiley-VCH

Purpose: To investigate the cerebrospinal fluid (CSF) proteome of patients with preeclampsia (PE) and normotensive pregnant women, in order to provide a better understanding of brain involvement in PE. Experimental design: Ninety-eight CSF samples (4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a144bd7afa6fabdca8b46904111307
https://hdl.handle.net/1765/104697