Latent TGFβ complexes are transglutaminase cross-linked to fibrillin to facilitate TGFβ activation.

Autor: Lockhart-Cairns MP; Wellcome Centre for Cell-Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PT, UK., Cain SA; Wellcome Centre for Cell-Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PT, UK., Dajani R; Wellcome Centre for Cell-Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PT, UK., Steer R; Wellcome Centre for Cell-Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PT, UK., Thomson J; Wellcome Centre for Cell-Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PT, UK., Alanazi YF; Wellcome Centre for Cell-Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PT, UK; Department of Biochemistry, Faculty of Science, University of Tabuk, Tabuk, Saudi Arabia., Kielty CM; Wellcome Centre for Cell-Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PT, UK., Baldock C; Wellcome Centre for Cell-Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester M13 9PT, UK. Electronic address: clair.baldock@manchester.ac.uk.

Publikováno v: Matrix biology : journal of the International Society for Matrix Biology [Matrix Biol] 2022 Mar; Vol. 107, pp. 24-39. Date of Electronic Publication: 2022 Feb 03.

ADAMTS10-mediated tissue disruption in Weill-Marchesani syndrome.

Autor: Mularczyk EJ; Wellcome Centre for Cell Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, UK.; Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK., Singh M; Wellcome Centre for Cell Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, UK.; Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK., Godwin ARF; Wellcome Centre for Cell Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, UK.; Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK., Galli F; Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK., Humphreys N; School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK., Adamson AD; School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK., Mironov A; School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK., Cain SA; Wellcome Centre for Cell Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, UK.; Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK., Sengle G; Center for Biochemistry, Center for Molecular Medicine (CMMC), Medical Faculty, University of Cologne, Germany., Boot-Handford RP; Wellcome Centre for Cell Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, UK.; Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK., Cossu G; Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK., Kielty CM; Wellcome Centre for Cell Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, UK.; Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK., Baldock C; Wellcome Centre for Cell Matrix Research, Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, UK.; Division of Cell-Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK.

Publikováno v: Human molecular genetics [Hum Mol Genet] 2018 Nov 01; Vol. 27 (21), pp. 3675-3687.

Extracellular Matrix Molecule-Based Capture of Mesenchymal Stromal Cells Under Flow.

Autor: Massam-Wu T; Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Biology, Medicine and Health, University of Manchester, Manchester, UK., Cain SA; Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Biology, Medicine and Health, University of Manchester, Manchester, UK., Kielty CM; Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Biology, Medicine and Health, University of Manchester, Manchester, UK. cay.kielty@manchester.ac.uk.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2018; Vol. 1722, pp. 249-260.

Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro.

Autor: Redondo-Castro E; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Cunningham C; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Miller J; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Martuscelli L; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Aoulad-Ali S; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Rothwell NJ; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Kielty CM; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.; Wellcome Trust Centre for Cell-Matrix Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Allan SM; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Pinteaux E; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK. emmanuel.pinteaux@manchester.ac.uk.

Publikováno v: Stem cell research & therapy [Stem Cell Res Ther] 2017 Apr 17; Vol. 8 (1), pp. 79. Date of Electronic Publication: 2017 Apr 17.

Independent multimerization of Latent TGFβ Binding Protein-1 stabilized by cross-linking and enhanced by heparan sulfate.

Autor: Troilo H; The Wellcome Trust Centre for Cell-Matrix Research is within the School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, M13 9PT, UK., Steer R; The Wellcome Trust Centre for Cell-Matrix Research is within the School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, M13 9PT, UK., Collins RF; The Wellcome Trust Centre for Cell-Matrix Research is within the School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, M13 9PT, UK., Kielty CM; The Wellcome Trust Centre for Cell-Matrix Research is within the School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, M13 9PT, UK., Baldock C; The Wellcome Trust Centre for Cell-Matrix Research is within the School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, M13 9PT, UK.

Publikováno v: Scientific reports [Sci Rep] 2016 Sep 28; Vol. 6, pp. 34347. Date of Electronic Publication: 2016 Sep 28.