In vivo interleukin-1 (IL-1) administration indirectly promotes type II IL-1 receptor expression on hematopoietic bone marrow cells: novel mechanism for the hematopoietic effects of IL-1

Autor: CM Dubois, FW Ruscetti, JR Keller, JJ Oppenheim, K Hestdal, R Chizzonite, R Neta

Publikováno v: Blood. 78:2841-2847

Interleukin-1 (IL-1) has profound stimulatory effects on hematopoiesis but the mechanism(s) of action remain unknown. The direct action of IL- 1 on hematopoietic progenitor cells requires the presence of a specific IL-1 receptor (IL-1R). In this repo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::025126b51324e875b876f1a715b4e803
https://doi.org/10.1182/blood.v78.11.2841.bloodjournal78112841

Hematopoietic growth factors and glucocorticoids synergize to mimic the effects of IL-1 on granulocyte differentiation and IL-1 receptor induction on bone marrow cells in vivo

Autor: Cm, Dubois, Neta R, Jr, Keller, Sten Eirik Waelgaard Jacobsen, Jj, Oppenheim, Ruscetti F

Publikováno v: Europe PubMed Central

The mechanisms by which interleukin-1 (IL-1) stimulates hematopoiesis are not clear. We have previously shown that in vivo administration of IL-1 indirectly increases IL-1 receptor (IL-1R) expression on both immature and mature bone marrow (BM) cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::598f4b23cfb6203602087238bc8dfdbf
https://pubmed.ncbi.nlm.nih.gov/7678814

Induction of colony-stimulating factor receptor expression on hematopoietic progenitor cells: proposed mechanism for growth factor synergism

Autor: Sten Eirik Waelgaard Jacobsen, Fw, Ruscetti, Cm, Dubois, Wine J, Jr, Keller

Publikováno v: Europe PubMed Central

In many cells systems, the cellular interaction between two or more humoral factors leads to a synergistic response in terms of cellular growth and function. In particular, the growth and differentiation of hematopoietic progenitor cells involves num

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb86a767bb632c933132737367b0619
https://pubmed.ncbi.nlm.nih.gov/1379087

Characterization and regulation of RB6-8C5 antigen expression on murine bone marrow cells

Autor: Hestdal K, Fw, Ruscetti, Jn, Ihle, Sten Eirik Waelgaard Jacobsen, Cm, Dubois, Wc, Kopp, Dl, Longo, Jr, Keller

Publikováno v: Europe PubMed Central

Murine bone marrow cells expressing the cell surface Ag RB6-8C5 were identified by fluorescence-activated cell-sorting analysis using a rat IgG mAb. The fluorescent intensity of RB6-8C5 was variable on bone marrow cells. This made it possible to sepa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2ee4244901e2935ae0b72e7fe4db16d8
https://pubmed.ncbi.nlm.nih.gov/1711076

Behavioral activation for veterans with co-occurring alcohol use disorder and posttraumatic stress disorder: Basis and methodology for a pilot randomized controlled trial.

Autor: Blakey SM; RTI International, 3040 E. Cornwallis Rd, P.O. Box 12194, Research Triangle Park, NC 27709-2194, USA. Electronic address: sblakey@rti.org., Alsobrooks AK; Duke University School of Medicine, Duke North Pavilion, 2400 Pratt Street, Durham, NC 27705, USA., Morgan-López AA; RTI International, 3040 E. Cornwallis Rd, P.O. Box 12194, Research Triangle Park, NC 27709-2194, USA., Kruskamp N; RTI International, 3040 E. Cornwallis Rd, P.O. Box 12194, Research Triangle Park, NC 27709-2194, USA., Simpson TL; University of Washington School of Medicine, 1959 NE Pacific Street, Seattle, WA 98195, USA; VA Puget Sound Health Care System, 1660 S. Columbian Way, Seattle, WA 98108, USA; Center of Excellence in Substance Addiction Treatment & Education, 1660 S. Columbian Way, Seattle, WA 98108, USA., Daughters SB; University of North Carolina at Chapel Hill, Department of Psychology and Neuroscience, CB 3270, Chapel Hill, NC 27599-3270, USA., DuBois CM; Duke University School of Medicine, Duke North Pavilion, 2400 Pratt Street, Durham, NC 27705, USA., Huang JS; Duke University School of Medicine, Duke North Pavilion, 2400 Pratt Street, Durham, NC 27705, USA., Evans J; Duke University School of Medicine, Duke North Pavilion, 2400 Pratt Street, Durham, NC 27705, USA., Serrano BN; Duke University School of Medicine, Duke North Pavilion, 2400 Pratt Street, Durham, NC 27705, USA., Calhoun PS; Duke University School of Medicine, Duke North Pavilion, 2400 Pratt Street, Durham, NC 27705, USA; Durham VA Health Care System, 508 Fulton Street, Durham, NC 27705, United States of America., Beckham JC; Duke University School of Medicine, Duke North Pavilion, 2400 Pratt Street, Durham, NC 27705, USA; Durham VA Health Care System, 508 Fulton Street, Durham, NC 27705, United States of America., Elbogen EB; Duke University School of Medicine, Duke North Pavilion, 2400 Pratt Street, Durham, NC 27705, USA.

Publikováno v: Contemporary clinical trials [Contemp Clin Trials] 2024 Nov; Vol. 146, pp. 107670. Date of Electronic Publication: 2024 Aug 24.