Výsledky vyhledávání - "Clyde O. Brindley"

Autor: Emil Frei, Vincent H. Bono, Clyde O. Brindley, Paul P. Carbone

Publikováno v: Blood. 21:640-647

Forty patients with malignant neoplastic disease received vincristine in an effort to define the toxicity, the tolerated dose, the effect of varying dose schedules, and the antitumor properties. The toxicity of vincristine is dose related, and the to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::29621c596a94a56639111a8075af190e
https://doi.org/10.1182/blood.v21.5.640.640

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A Controlled Trial of Urethane Treatment in Multiple Myeloma

Autor: G. Lennard Gold, Henry F. Hosley, Thomas C. Hall, James F Holland, Albert H. Owens, Emil Frei, Louis Lasagna, Carol Scharlau, Bruce I. Shnider, Clyde O. Brindley, Paul P. Carbone, Sherwood P. Miller

Publikováno v: Blood. 27:328-342

Patients with multiple myeloma were stratified according to prior treatment and randomly assigned to coded urethane or placebo syrup administration. Urethane administration was of shorter duration than placebo treatment, but was associated, in patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4941cba37a475d6ab51527da3adfdfb6
https://doi.org/10.1182/blood.v27.3.328.328

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Further comparative trial of triethylene thiophosphoramide and mechlorethamine in patients with Melanoma and Hodgkin's disease

Autor: K.Gale Potee, Bruce I. Shnider, Barbara Lipowska, Leonard G. Salvin, Jacob Colsky, Clyde O. Brindley, William Regelson

Publikováno v: Journal of Chronic Diseases. 17:19-30

A comparative trial was carried out by the Eastern Cooperative Group in Solid Tumor Chemotherapy in 49 patients with melanoma and 48 patients with Hodgkin's disease with the two alkylating agents methyl-bis (β-chloroethyl)amine hydrochloride (HN 2 )

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba469a744dfc66863d2038061d23350
https://doi.org/10.1016/0021-9681(64)90036-0

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Laboratory and Clinical Studies with the Riboflavin Antagonist, Galactoflavin

Autor: Montague Lane, Clyde O. Brindley

Publikováno v: Experimental Biology and Medicine. 116:57-61

Summary1. The riboflavin analog, 10-d-dulcityl-7,8-dimethyl-isoalloxazine (galactoflavin), was absorbed following oral administration to rats and to human patients. Plasma flavin levels and urine flavin excretion were greater in humans than in rodent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b18a72991a0a3cd4958624adefc00fe
https://doi.org/10.3181/00379727-116-29158

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Comparative trial of chemotherapy and radiotherapy in patients with non-resectable cancer of the lung

Autor: Charles Hunter, Edmund A. Gehan, Clyde O. Brindley, Emil Frei, Melvin J. Krant, Hugo Muench, Martin B. Levene, Thomas C. Hall, Albert H. Owens, Kirkland C. Brace, Bruce I. Shnider, Natividad de Leon, Robert J. Dickson, G. Lennard Gold, Thomas C. Chalmers, Margarida M. Dederick, Leonard G. Salvin, Solomon R. Bersack

Publikováno v: The American Journal of Medicine. 35:363-373

Two hundred and nineteen patients with carcinoma of the lung were studied in three treatment groups in a cooperative in-hospital study. Of these patients, 196 had not received prior therapy. Treatment group I was given a mean of 3,843 tissue r., trea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c2b005ac3ba00c8d2ac24d55fb45ec0
https://doi.org/10.1016/0002-9343(63)90178-5

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Appraisal of methods for the study of chemotherapy of cancer in man: Comparative therapeutic trial of nitrogen mustard and triethylene thiophosphoramide

Autor: William Regelson, Zubrod Cg, Clyde O. Brindley, Emil Frei, Thomas C. Chalmers, Raul G. Oviedo, Oleg S. Selawry, Ulfar Jonsson, John Gorman, Louis Lasagna, Bruce I. Shnider, G. Lennard Gold, Albert H. Owens, Margarida M. Dederick, Ralph Jones, Bruce Ferguson, James F. Holland, Marvin A. Schneiderman, Jack Colsky

Publikováno v: Journal of Chronic Diseases. 11:7-33

Suggestions are made for the conduct of chemotherapy trials in patients with cancer. Application of the principles involved are illustrated in a comparative study of triethylene thiophosphoramide and nitrogen mustard in cancer of the lung and breast,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ad6227be0b8e4ed2ae68b6ade6143b3
https://doi.org/10.1016/0021-9681(60)90137-5

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