Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Clyde K. Yamashita"'
Autor:
Donald A. Fox, Rıza Köksal Özgül, Emmanuel Mendoza, J. E. Johnson, Clyde K. Yamashita, Novruz B. Ahmedli, Collins C. Njoku, Akash Naidu, Alejandra Young, Yekaterina E. Gribanova, Debora B. Farber
Publikováno v:
Journal of Biological Chemistry. 288:9742-9754
The novel rhomboid-like protein RHBDD2 is distantly related to rhomboid proteins, a group of highly specialized membrane-bound proteases that catalyze regulated intramembrane proteolysis. In retina, RHBDD2 is expressed from embryonic stages to adulth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a50e8b35cfb9b1463b576574a2ba2c
https://doi.org/10.1074/jbc.m112.419960
https://doi.org/10.1074/jbc.m112.419960
Autor:
Clyde K. Yamashita, Debora B. Farber, Gustavo D. Aguirre, Dai Tran, Natik Piri, N. B. Akhmedov
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1728:11-17
The large tumor suppressor gene (Lats1) encodes a protein kinase that is highly conserved from fly to human, and plays a crucial role in the prevention of tumor formation by controlling mitosis progression. We have found that in addition to the previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b16fcb6f4843fe0e0b9b35882e59584f
https://doi.org/10.1016/j.bbaexp.2005.01.003
https://doi.org/10.1016/j.bbaexp.2005.01.003
Publikováno v:
Journal of Biological Chemistry. 278:36999-37005
The catalytic core of photoreceptor-specific cGMP-phosphodiesterase (PDE) consists of two subunits, PDEα and PDEβ, that are homologous and have similar domain organization but are encoded by different genes. We have examined the PDEα and PDEβ mRN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8210b24268b9fdd2a00749a4a31c459
https://doi.org/10.1074/jbc.m303710200
https://doi.org/10.1074/jbc.m303710200
Publikováno v:
The Journal of Neuroscience. 23:6030-6040
Usually, photoreceptors interact with other retinal cells through the neurotransmitter glutamate. Here we describe a nonsynaptic interaction via a secreted protein, retinoschisin. Usingin situhybridization, we found that from early postnatal life ret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ececd538581937efae2d578b3fabaf14
https://doi.org/10.1523/jneurosci.23-14-06030.2003
https://doi.org/10.1523/jneurosci.23-14-06030.2003
Autor:
Chyuan-Sheng Lin, Clyde K. Yamashita, Debora B. Farber, Stephen H. Tsang, Peter Gouras, Stephen P. Goff, Won Ho Lee
Publikováno v:
Vision Research. 42(4):439-445
The inhibitory rod cyclic GMP-phosphodiesterase gamma subunit, PDEgamma, is a key component of the photoresponse and is required to support rod integrity. Pdeg(tm1)/Pdeg(tm1) mice that lack PDEgamma due to a targeted disruption of the gene encoding P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d829d874ea9055728e109609efa782
Autor:
Debora B. Farber, Michael L. Woodruff, Clyde K. Yamashita, Robert Smith Pedersen, Stephen H. Tsang, Chyuan-Sheng Lin, Michael Larsen, Lin Jun, Thomas Rosenberg, Mahajan Vinit, Steven Nusinowitz, Stephen P. Goff
Mutations in the beta-subunit of cGMP-phosphodiesterase (PDE6beta) can lead to either progressive retinal disease, such as human retinitis pigmentosa (RP), or stationary disease, such as congenital stationary night blindness (CSNB). Individuals with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d4c174d10abb24f1cdd7d464a3e15e5
https://europepmc.org/articles/PMC2753261/
https://europepmc.org/articles/PMC2753261/
Autor:
Natik Piri, Clyde K. Yamashita, Jennifer Shih, Emmanuel Mendoza, N. B. Akhmedov, Debora B. Farber
Publikováno v:
Experimental eye research. 83(4)
We have established earlier that rod photoreceptor cGMP-phosphodiesterase (PDE6) alpha and beta subunits are equally represented in the retina at the protein level and have similar turnover rates. mRNA quantification revealed five PDE6beta messages f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14009547214fd237d009c7e7677788b8
https://pubmed.ncbi.nlm.nih.gov/16765946
https://pubmed.ncbi.nlm.nih.gov/16765946
Publikováno v:
The Journal of biological chemistry. 278(39)
The catalytic core of photoreceptor-specific cGMP-phosphodiesterase (PDE) consists of two subunits, PDEalpha and PDEbeta, that are homologous and have similar domain organization but are encoded by different genes. We have examined the PDEalpha and P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::084b4d93437b53e66626fd82d22afeb3
https://pubmed.ncbi.nlm.nih.gov/12871955
https://pubmed.ncbi.nlm.nih.gov/12871955
Publikováno v:
Molecular vision. 9
A functional protein is required for structure/function analysis of cone photoreceptor cGMP-phosphodiesterase alpha' subunit (PDEalpha'). The purpose of this study was to express enzymatically active PDEalpha'.Three expression vectors were constructe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5a89801d6cf71d1ea565890d8d70483
https://pubmed.ncbi.nlm.nih.gov/12655284
https://pubmed.ncbi.nlm.nih.gov/12655284
Publisher Summary This chapter includes all the protocols required to construct and test EAMs with any transgene of interest. A discussion of the main features of the different types of EAMs and of the modified protocols, developed for analysis of EA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::558c076fadd82b8dbfedd8bb881c0362
https://doi.org/10.1016/s0076-6879(00)16759-x
https://doi.org/10.1016/s0076-6879(00)16759-x