Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Clovis S Palmer"'
Publikováno v:
Clinical & Translational Immunology, Vol 8, Iss 11, Pp n/a-n/a (2019)
Abstract It is now clear that access to specific metabolic programmes controls the survival and function of various immune cell populations, including T cells. Efficient naïve and memory T cell homoeostasis requires the use of specific metabolic pat
Externí odkaz:
https://doaj.org/article/fc1a5a4638df4d8f8d4ee10bd300ad50
Autor:
Clovis S. Palmer, Chrysostomos Perdios, Mohamed Abdel-Mohsen, Joseph Mudd, Prasun K. Datta, Nicholas J. Maness, Gabrielle Lehmicke, Nadia Golden, Linh Hellmers, Carol Coyne, Kristyn Moore Green, Cecily Midkiff, Kelsey Williams, Rafael Tiburcio, Marissa Fahlberg, Kyndal Boykin, Carys Kenway, Kasi Russell-Lodrigue, Angela Birnbaum, Rudolf Bohm, Robert Blair, Jason P. Dufour, Tracy Fischer, Ahmad A. Saied, Jay Rappaport
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Hyperglycemia, and exacerbation of pre-existing deficits in glucose metabolism, are manifestations of the post-acute sequelae of SARS-CoV-2. Our understanding of metabolic decline after acute COVID-19 remains unclear due to the lack of anima
Externí odkaz:
https://doaj.org/article/f08910814723411b8c7b83f16cf5d078
Autor:
Jesse J R Masson, Andrew J Murphy, Man K S Lee, Matias Ostrowski, Suzanne M Crowe, Clovis S Palmer
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183931 (2017)
Metabolism plays a fundamental role in supporting the growth, proliferation and effector functions of T cells. We investigated the impact of HIV infection on key processes that regulate glucose uptake and mitochondrial biogenesis in subpopulations of
Externí odkaz:
https://doaj.org/article/442c69c097fe4db091d8035613d003c6
Autor:
Genevieve E Martin, Maelenn Gouillou, Anna C Hearps, Thomas A Angelovich, Allen C Cheng, Fiona Lynch, Wan-Jung Cheng, Geza Paukovics, Clovis S Palmer, Richard M Novak, Anthony Jaworowski, Alan L Landay, Suzanne M Crowe
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55279 (2013)
Aging is associated with immune dysfunction and the related development of conditions with an inflammatory pathogenesis. Some of these immune changes are also observed in HIV infection, but the interaction between immune changes with aging and HIV in
Externí odkaz:
https://doaj.org/article/f27ee7ace80b47d3b2b345e51fbe26a5
Autor:
Leila B. Giron, Clovis S. Palmer, Qin Liu, Xiangfan Yin, Emmanouil Papasavvas, Radwa Sharaf, Behzad Etemad, Mohammad Damra, Aaron R. Goldman, Hsin-Yao Tang, Rowena Johnston, Karam Mounzer, Jay R. Kostman, Pablo Tebas, Alan Landay, Luis J. Montaner, Jeffrey M. Jacobson, Jonathan Z. Li, Mohamed Abdel-Mohsen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Current HIV cure-focused clinical trials rely on analytic treatment interruption (ATI) to evaluate post-treatment control (PTC). Here, combining untargetted metabolomics and glycomics in two HIV clinical cohorts, in vitro assays, and machine learning
Externí odkaz:
https://doaj.org/article/8389144aeb1a4d6d950f9fd144f01fe1
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/b6665e1cc3c34756b6ba3ec8c184a30b
Autor:
Leila B. Giron, Harsh Dweep, Xiangfan Yin, Han Wang, Mohammad Damra, Aaron R. Goldman, Nicole Gorman, Clovis S. Palmer, Hsin-Yao Tang, Maliha W. Shaikh, Christopher B. Forsyth, Robert A. Balk, Netanel F. Zilberstein, Qin Liu, Andrew Kossenkov, Ali Keshavarzian, Alan Landay, Mohamed Abdel-Mohsen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/9d43aa506dba4c96a60a71df485dd3a5
Autor:
Leila B. Giron, Harsh Dweep, Xiangfan Yin, Han Wang, Mohammad Damra, Aaron R. Goldman, Nicole Gorman, Clovis S. Palmer, Hsin-Yao Tang, Maliha W. Shaikh, Christopher B. Forsyth, Robert A. Balk, Netanel F. Zilberstein, Qin Liu, Andrew Kossenkov, Ali Keshavarzian, Alan Landay, Mohamed Abdel-Mohsen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
A disruption of the crosstalk between the gut and the lung has been implicated as a driver of severity during respiratory-related diseases. Lung injury causes systemic inflammation, which disrupts gut barrier integrity, increasing the permeability to
Externí odkaz:
https://doaj.org/article/106b035c6b02411ea9bcfd98efbe5a57
Autor:
Leila B. Giron, Emmanouil Papasavvas, Xiangfan Yin, Aaron R. Goldman, Hsin-Yao Tang, Clovis S. Palmer, Alan L. Landay, Jonathan Z. Li, John R. Koethe, Karam Mounzer, Jay R. Kostman, Qin Liu, Luis J. Montaner, Mohamed Abdel-Mohsen
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
The likelihood of HIV rebound after stopping antiretroviral therapy (ART) is a combination of the size of HIV reservoirs that persist despite ART and the host immunological and inflammatory factors that control these reservoirs. Therefore, there is a
Externí odkaz:
https://doaj.org/article/0fa9e9d892ae46d3801779a44629a2bb
Autor:
Florent Colomb, Leila B. Giron, Leticia Kuri-Cervantes, Opeyemi S. Adeniji, Tongcui Ma, Harsh Dweep, Emilie Battivelli, Eric Verdin, Clovis S. Palmer, Hiroaki Tateno, Andrew V. Kossenkov, Nadia R. Roan, Michael R. Betts, Mohamed Abdel-Mohsen
Publikováno v:
Cell Reports, Vol 32, Iss 5, Pp 107991- (2020)
Summary: A comprehensive understanding of the phenotype of persistent HIV-infected cells, transcriptionally active and/or transcriptionally inactive, is imperative for developing a cure. The relevance of cell-surface glycosylation to HIV persistence
Externí odkaz:
https://doaj.org/article/7a931a3a4ffc4ff0895673a8784b2743