Instant coffee with high chlorogenic acid levels protects humans against oxidative damage of macromolecules

Autor: Armen Nersesyan, Leonilla Elbling, Benoît Schilter, Christophe Cavin, Claudine Bezençon, Maricel Marin-Kuan, Michael Kundi, Siegfried Knasmüller, Thierry Delatour, Karl-Heinz Wagner, Oliver Neubauer, Dominik Grathwohl, Christine Hoelzl, Amélie Besson, Franziska Ferk, Veronika Ehrlich, Clotilde Verguet, Nina Kager, Wolfgang W. Huber, Tatjana Simic, Aurélien Desmarchelier

Publikováno v: Molecular Nutrition & Food Research. 54:1722-1733

Scope: Coffee is among the most frequently consumed beverages. Its consumption is inversely associated to the incidence of diseases related to reactive oxygen species; the phenomenon may be due to its antioxidant properties. Our primary objective was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f219da7e6bcce0fc591cfefa2860c0
https://doi.org/10.1002/mnfr.201000048

Induction of Nrf2-mediated cellular defenses and alteration of phase I activities as mechanisms of chemoprotective effects of coffee in the liver

Autor: Christophe Cavin, G. Guignard, Sophie Langouët, Claudine Bezençon, Benoît Schilter, D. Holzhäuser, Maricel Marin-Kuan, Dominique Piguet, R. Cornaz, Clotilde Verguet

Publikováno v: Food and Chemical Toxicology
Food and Chemical Toxicology, Elsevier, 2008, 46 (4), pp.1239-48. ⟨10.1016/j.fct.2007.09.099⟩
Food and Chemical Toxicology, 2008, 46 (4), pp.1239-48. ⟨10.1016/j.fct.2007.09.099⟩

International audience; Coffee consumption has been associated with a significant decrease in the risk of developing chronic diseases such as Parkinson disease, diabetes type-2 and several types of cancers (e.g. colon, liver). In the present study, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e72f7e7702e256fd3eccb33bf7c796
https://pubmed.ncbi.nlm.nih.gov/17976884

A toxicogenomics approach to identify new plausible epigenetic mechanisms of ochratoxin a carcinogenicity in rat

Autor: Peter G. Mantle, Sandra Nestler, Maricel Marin-Kuan, Christophe Cavin, Dominique Piguet, M. Grigorov, Thierry Delatour, Claudine Bezençon, R. Mansourian, Clotilde Verguet, Benoît Schilter, J. Holzwarth

Publikováno v: Toxicological sciences : an official journal of the Society of Toxicology. 89(1)

Ochratoxin A (OTA) is a mycotoxin occurring naturally in a wide range of food commodities. In animals, it has been shown to cause a variety of adverse effects, nephrocarcinogenicity being the most prominent. Because of its high toxic potency and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb549717cf670a4931f4ecfe4d0579a
https://pubmed.ncbi.nlm.nih.gov/16251485