Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Clotilde Descarpentries"'
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Akademický článek
MET exon 14 skipping mutation is a hepatocyte growth factor (HGF)‐dependent oncogenic driver in vitro and in humanised HGF knock‐in mice
Autor: Marie Fernandes, Brynna Hoggard, Philippe Jamme, Sonia Paget, Marie‐José Truong, Valérie Grégoire, Audrey Vinchent, Clotilde Descarpentries, Angela Morabito, Justas Stanislovas, Enoir Farage, Jean‐Pascal Meneboo, Shéhérazade Sebda, Katia Bouchekioua‐Bouzaghou, Marie Nollet, Sarah Humez, Timothy Perera, Paul Fromme, Luca Grumolato, Martin Figeac, Marie‐Christine Copin, David Tulasne, Alexis B. Cortot, Stéphanie Kermorgant, Zoulika Kherrouche
Publikováno v: Molecular Oncology, Vol 17, Iss 11, Pp 2257-2274 (2023)
Exon skipping mutations of the MET receptor tyrosine kinase (METex14), increasingly reported in cancers, occur in 3–4% of non–small‐cell lung cancer (NSCLC). Only 50% of patients have a beneficial response to treatment with MET‐tyrosine kinas
Externí odkaz: https://doaj.org/article/272f451e35f5414da2913aa27cf75f12
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2
Akademický článek
Tyrosine kinase inhibitors induce down-regulation of c-Kit by targeting the ATP pocket.
Autor: Diane D'allard, Julie Gay, Clotilde Descarpentries, Emilie Frisan, Kevin Adam, Frederique Verdier, Célia Floquet, Patrice Dubreuil, Catherine Lacombe, Michaela Fontenay, Patrick Mayeux, Olivier Kosmider
Publikováno v: PLoS ONE, Vol 8, Iss 4, p e60961 (2013)
The stem cell factor receptor (SCF) c-Kit plays a pivotal role in regulating cell proliferation and survival in many cell types. In particular, c-Kit is required for early amplification of erythroid progenitors, while it must disappear from cell surf
Externí odkaz: https://doaj.org/article/fa067dc590e84f4ea8744597e596650e
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6
Response to Capmatinib in a MET Fusion-Positive Cholangiocarcinoma
Autor: Anthony Turpin, Clotilde Descarpentries, Valérie Grégoire, Olivier Farchi, Alexis B Cortot, Philippe Jamme
Publikováno v: The oncologist.
Cholangiocarcinoma is the second most common liver cancer after hepatocellular carcinoma. In case of metastatic or unresectable disease, the recommended first-line treatment is gemcitabine-based doublet, most commonly gemcitabine and cisplatin. There
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a349e5f4e6f3d9c4d1d4fd34b8bd2e6e
https://pubmed.ncbi.nlm.nih.gov/36434677
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7
Spatial heterogeneity of KRAS mutations in colorectal cancers in northern France
Autor: Francis Vasseur, Florent Occelli, Anthony Turpin, Michaël Genin, Caroline Lanier, Clotilde Descarpentries, Diane Pannier, Anne Ploquin, Mohamed Hebbar
Publikováno v: Cancer Management and Research. 11:8337-8344
Background Somatic mutations in the KRAS gene are the most common oncogenic mutations found in human cancers. However, no clinical features have been linked to KRAS mutations in colorectal cancer [CRC]. Purpose In this study, we attempted to identify
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cc613cdd824dcb0b05fa688f528718ce
https://doi.org/10.2147/cmar.s211119
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8
MET kinase mutations in lung cancer patients
Autor: Louise Kalmuk, Clotilde Descarpentries, Celine Mascaux, Camille Munck, Zoulika Kherrouche, Eric Wasielewski, Lucie Ulmer, Olivier Farchi, Fabienne Escande, Michele Beau-Faller, Alexis B Cortot
Publikováno v: Journal of Clinical Oncology. 40:e21014-e21014
e21014 Background: Although mutations in the kinase domain of MET are well described in papillary renal cell carcinoma, they are rare and poorly studied in lung cancer, but could constitute a new therapeutic target given the availability of potent ME
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52b8199f82fdfe3e9f42d4d39a8a9bf0
https://doi.org/10.1200/jco.2022.40.16_suppl.e21014
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9
Akademický článek
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10
Three Rounds of External Quality Assessment in France to Evaluate the Performance of 28 Platforms for Multiparametric Molecular Testing in Metastatic Colorectal and Non-Small Cell Lung Cancer
Autor: Han van Krieken, Dominique Fetique, Jean-François Emile, Etienne Lonchamp, Jean-Michel Vignaud, Bastiaan B J Tops, Isabelle Soubeyran, Jean-François Côté, Caroline Egele, Catherine Andrieu, Hélène Blons, Etienne Rouleau, Cédric Le Maréchal, Marjolijn J. L. Ligtenberg, Cleo Keppens, Clotilde Descarpentries, Elisabeth Dequeker, Jean-Christophe Sabourin, Antoinette Lemoine, Valérie Duranton-Tanneur, Sofie Delen, Paul Hofman, Frédérique Penault-Llorca, Jean-Pierre Bellocq, Florence Pedeutour, Yves Denoux, Aude Lamy, Frédérique Nowak, Nathalie Monhoven, Karen Leroy, Cecile Aube, Pierre Laurent-Puig, Véronique Haddad, Laurent Doucet
Publikováno v: Journal of Molecular Diagnostics
Journal of Molecular Diagnostics, 2016, 18 (2), pp.205-214. ⟨10.1016/j.jmoldx.2015.09.004⟩
Journal of Molecular Diagnostics, American Society for Investigative Pathology (ASIP), 2016, 18 (2), pp.205-214. ⟨10.1016/j.jmoldx.2015.09.004⟩
Journal of Molecular Diagnostics, 18, 205-14
Journal of Molecular Diagnostics, 18, 2, pp. 205-14
Contains fulltext : 171799.pdf (Publisher’s version ) (Closed access) Personalized medicine has gained increasing importance in clinical oncology, and several clinically important biomarkers are implemented in routine practice. In an effort to guar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e660b35a4d3585da23e1bde4881f741e
https://hal.univ-lorraine.fr/hal-01666600
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