The centrosomal protein 131 participates in the regulation of mitochondrial apoptosis

Autor: Clotilde C. N. Renaud, Kilian Trillet, Jane Jardine, Laura Merlet, Ophélie Renoult, Mélanie Laurent—Blond, Zoé Catinaud, Claire Pecqueur, Julie Gavard, Nicolas Bidère

Publikováno v: Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)

Abstract Centriolar satellites are multiprotein aggregates that orbit the centrosome and govern centrosome homeostasis and primary cilia formation. In contrast to the scaffold PCM1, which nucleates centriolar satellites and has been linked to microtu

Externí odkaz: https://doaj.org/article/26a3a8f1e2c3405aa8a54012480e6f59

Serine 165 Phosphorylation of SHARPIN regulates the Activation of NF-κB

Autor: Nicolas Bidère, Charles Pineau, An Thys, Emmanuelle Com, Audrey Gayraud, Clotilde C. N. Renaud, Tiphaine Douanne, Franck Vérité, Julie Gavard, Kilian Trillet, Yannic Danger, Sara Rosińska, Régis Lavigne, Luc Antigny

Publikováno v: iScience
iScience, 2021, 24 (1), pp.101939. ⟨10.1016/j.isci.2020.101939⟩
iScience, Vol 24, Iss 1, Pp 101939-(2021)
iScience, Elsevier, 2021, 24 (1), pp.101939. ⟨10.1016/j.isci.2020.101939⟩

Summary The adaptor SHARPIN composes, together with the E3 ligases HOIP and HOIL1, the linear ubiquitin chain assembly complex (LUBAC). This enzymatic complex catalyzes and stamps atypical linear ubiquitin chains onto substrates to modify their fate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b6337414d713aee7f480e324962703
https://hal.science/hal-02991405/document