Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Cloricromene"'
Autor:
Achille P. Caputi, Giuseppe M. Campo, Sergio Sturiale, Giacomo Carlo Sturniolo, Maria Lo Presti, Emanuela Mazzon, G. Longo, M.R. Giofré, Walter Fries, Salvatore Cuzzocrea
Publikováno v:
Life sciences. 74(22)
Biologic therapies, namely antibodies against tumor necrosis factor-alpha (TNF- alpha) or its receptors, have been recently introduced for the treatment of patients with inflammatory bowel disease (IBD). In the present study the effects of cloricrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361b1f69a612eaa3eef6a7acf292a403
https://pubmed.ncbi.nlm.nih.gov/15043989
https://pubmed.ncbi.nlm.nih.gov/15043989
Autor:
Giampiero Mazzaglia, Gioacchino Calapai, Maria C. Marciano, Francesco Squadrito, Basilia Zingarelli, Marco Prosdocimi, Achille P. Caputi, Domenica Altavilla
Publikováno v:
Life Sciences. 51:2041-2048
Intravenous (640 micrograms/kg) or intracerebroventricular (0.5 and 1 microgram) injection of Escherichia coli endotoxin (LPS) causes inhibition of water intake induced by 24 hour period of water deprivation in the rat. Tumor necrosis factor alpha (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf36f881b991b2522d1a69cd5c461dc2
https://doi.org/10.1016/0024-3205(92)90154-h
https://doi.org/10.1016/0024-3205(92)90154-h
Publikováno v:
European Journal of Pharmacology. 198:97-100
Cloricromene inhibits the activation of platelets and polymorphonuclear leukocytes (PMN) induced by specific stimuli. We report here that cloricromene caused a concentration-dependent reduction of platelet aggregation, β-thromboglobulin (β-TG) rele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac90cfe8d34b7841903cf75d8a3fbffb
https://doi.org/10.1016/0014-2999(91)90568-b
https://doi.org/10.1016/0014-2999(91)90568-b
Publikováno v:
The Journal of pharmacy and pharmacology. 58(7)
The pharmacokinetics of a lipophilic alkylamino acid (LAA) prodrug of cloricromene (AD6), namely CLOR-C4, was studied in rat plasma and brain. In particular, we observed that the intraperitoneal administration of CLOR-C4 to rats was able to provide a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff205dee27779ff0a784b1f1f195c27
https://pubmed.ncbi.nlm.nih.gov/16805962
https://pubmed.ncbi.nlm.nih.gov/16805962
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Rosario Pignatello, Barbara Busà, Giovanni Puglisi, Francesco Maugeri, Claudio Bucolo, Adriana Maltese
Publikováno v:
The Journal of pharmacy and pharmacology. 56(7)
A Eudragit RL100 polymer nanoparticle system loaded with cloricromene was prepared and characterized on the basis of physicochemical properties, stability and drug release features. To investigate the ocular bioavailability of cloricromene after incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba9c9a78bf2275a63234bb8592543e9
https://pubmed.ncbi.nlm.nih.gov/15233861
https://pubmed.ncbi.nlm.nih.gov/15233861
Autor:
Angela Ianaro, Gianluca Grassia, M. Di Rosa, Raffaella Sorrentino, Armando Ialenti, Pasquale Maffia, P. Di Meglio, R. d’Emmanuele di Villa Bianca
In this study we investigated, for the first time in vivo, the effect of cloricromene, a cumarine derivative, on NF-kappaB activation in endotoxin-treated rats. Endotoxemia was induced in male rats by the intravenous injection of Salmonella typhosa l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc173b22f344490ddaaa9d2a2a557f6
http://hdl.handle.net/11588/702183
http://hdl.handle.net/11588/702183
Publikováno v:
Cardiology. 84(4-5)
Cloricromene (Clo) has been used to prevent myocardial damage after transient occlusion of the circumflex coronary artery (Cx). Twenty rabbits were injected for 4 days with a single dose of Clo (0.25 mg/kg i.v.) or placebo. On the 5th day, the Cx was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0662b10f8fcfab7dfb68fdf504005fff
https://pubmed.ncbi.nlm.nih.gov/8187114
https://pubmed.ncbi.nlm.nih.gov/8187114
Autor:
Mariapatrizia Ioculano, Domenica Altavilla, Alfredo Miceli, Giuseppe M. Campo, Gioacchino Calapai, Basilia Zingarelli, Archille P. Caputi, Francesco Squadrito, Marco Prosdocimi
Publikováno v:
Life sciences. 53(4)
The effects of cloricromene, a coumarine derivative, were studied in an anaesthetized rat model of coronary artery ligation (60 min) followed by reperfusion (60 min; MI/R). Sham operated rats were used as controls (Sham MI/R). Myocardial ischaemia-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0bc793a15b657e95825aa2f683a24c3
https://pubmed.ncbi.nlm.nih.gov/8392130
https://pubmed.ncbi.nlm.nih.gov/8392130