Targeting endothelial cell anergy to improve CAR T cell therapy for solid tumors.

Autor: Wachholz GE; Angiogenesis Laboratory, Department of Medical Oncology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam, the Netherlands., Akbari P; Angiogenesis Laboratory, Department of Medical Oncology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam, the Netherlands., Huijbers EJM; Angiogenesis Laboratory, Department of Medical Oncology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam, the Netherlands., Jalan P; Angiogenesis Laboratory, Department of Medical Oncology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam, the Netherlands., van Beijnum JR; Angiogenesis Laboratory, Department of Medical Oncology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam, the Netherlands., Griffioen AW; Angiogenesis Laboratory, Department of Medical Oncology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam, the Netherlands. Electronic address: a.griffioen@amsterdamumc.nl.

Publikováno v: Biochimica et biophysica acta. Reviews on cancer [Biochim Biophys Acta Rev Cancer] 2024 Sep; Vol. 1879 (5), pp. 189155. Date of Electronic Publication: 2024 Jul 15.

BATF represses BIM to sustain tolerant T cells in the periphery.

Autor: Titcombe PJ; Department of Medicine, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN, USA., Silva Morales M; Department of Medicine, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN, USA., Zhang N; Department of Medicine, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN, USA., Mueller DL; Department of Medicine, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN, USA.

Publikováno v: The Journal of experimental medicine [J Exp Med] 2023 Dec 04; Vol. 220 (12). Date of Electronic Publication: 2023 Oct 20.

Dysfunctional natural killer cells can be reprogrammed to regain anti-tumor activity.

Autor: Sabag B; The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, 5290002, Israel., Puthenveetil A; The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, 5290002, Israel., Levy M; The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, 5290002, Israel., Joseph N; The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, 5290002, Israel., Doniger T; The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, 5290002, Israel., Yaron O; The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, 5290002, Israel., Karako-Lampert S; The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, 5290002, Israel., Lazar I; The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, 5290002, Israel., Awwad F; The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, 5290002, Israel., Ashkenazi S; The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, 5290002, Israel., Barda-Saad M; The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, 5290002, Israel. Mira.Barda-Saad@biu.ac.il.

Publikováno v: The EMBO journal [EMBO J] 2024 Jul; Vol. 43 (13), pp. 2552-2581. Date of Electronic Publication: 2024 Apr 18.

Silencing and activating anergic B cells.

Autor: Tanaka S; Division of Immunology and Genome Biology, Department of Molecular Genetics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan., Ise W; Team of Host Defense, Center for Infectious Disease Education and Research, Osaka University, Osaka, Japan.; Laboratory of Lymphocyte Differentiation, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan., Baba Y; Division of Immunology and Genome Biology, Department of Molecular Genetics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan., Kurosaki T; Laboratory of Lymphocyte Differentiation, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan.; Division of Microbiology and Immunology, Center for Infectious Disease Education and Research, Osaka University, Osaka, Japan.; Laboratory of Lymphocyte Differentiation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.

Publikováno v: Immunological reviews [Immunol Rev] 2022 May; Vol. 307 (1), pp. 43-52. Date of Electronic Publication: 2021 Dec 14.

Microbial Protein Binding to gC1qR Drives PLA2G1B-Induced CD4 T-Cell Anergy.

Autor: Pothlichet J; DIACCURATE, Paris, France., Meola A; DIACCURATE, Paris, France., Bugault F; DIACCURATE, Paris, France., Jeammet L; DIACCURATE, Paris, France., Savitt AG; Division of Rheumatology, Allergy, and Clinical Immunology, Department of Medicine, SUNY Stony Brook, Stony Brook, NY, United States., Ghebrehiwet B; Division of Rheumatology, Allergy, and Clinical Immunology, Department of Medicine, SUNY Stony Brook, Stony Brook, NY, United States., Touqui L; Cystic Fibrosis and Bronchial Diseases team - INSERM U938, Institut Pasteur, Paris, France.; Centre de Recherche Saint-Antoine (CRSA) - INSERM UMRS938, Sorbonne Université, Paris, France., Pouletty P; Truffle Capital, Paris, France., Fiore F; Centre d'Immunophénomique, Aix Marseille Université, INSERM, CNRS, Marseille, France., Sauvanet A; Service de Chirurgie Hépatobiliaire et Pancréatique - Department of HBP Surgery, Hôpital Beaujon - University of Paris, Clichy, France., Thèze J; DIACCURATE, Paris, France.

Publikováno v: Frontiers in immunology [Front Immunol] 2022 Mar 22; Vol. 13, pp. 824746. Date of Electronic Publication: 2022 Mar 22 (Print Publication: 2022).