Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Clive Standley"'
Autor:
Yongrong Zhang, Lianfa Shi, Shan Li, Zhiyong Yang, Clive Standley, Zhong Yang, Ronghua ZhuGe, Tor Savidge, Xiaoning Wang, Hanping Feng
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58634 (2013)
Clostridium difficile toxin B (TcdB) intoxicates target cells by glucosylating Rho GTPases. TcdB (269 kDa) consists of at least 4 functional domains including a glucosyltransferase domain (GTD), a cysteine protease domain (CPD), a translocation domai
Externí odkaz:
https://doaj.org/article/1ab62a8271c4463bbc5cc25f0128fb52
Autor:
Agata Jurczyk, Steven C Pino, Bryan O'Sullivan-Murphy, Martha Addorio, Erich A Lidstone, Philip Diiorio, Kathryn L Lipson, Clive Standley, Kevin Fogarty, Lawrence Lifshitz, Fumihiko Urano, John P Mordes, Dale L Greiner, Aldo A Rossini, Rita Bortell
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11812 (2010)
The centrosome is important for microtubule organization and cell cycle progression in animal cells. Recently, mutations in the centrosomal protein, pericentrin, have been linked to human microcephalic osteodysplastic primordial dwarfism (MOPD II), a
Externí odkaz:
https://doaj.org/article/87eb60336d2e4579be48ca104bae968e
Autor:
Deanna M. Navaroli, Socheata Ly, Dimas Echeverria, Marie-Cecile Didiot, Karl D. Bellve, Kevin E. Fogarty, Anastasia Khvorova, James Cardia, Matthieu Prot, Julia F. Alterman, Clive Standley, Lakshmipathi Pandarinathan, Lawrence M. Lifshitz, Silvia Corvera
Publikováno v:
Nucleic Acids Research
siRNAs are a new class of therapeutic modalities with promising clinical efficacy that requires modification or formulation for delivery to the tissue and cell of interest. Conjugation of siRNAs to lipophilic groups supports efficient cellular uptake
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c62a29ec3289750f4c50e61492bf7019
https://doi.org/10.1093/nar/gkw1005
https://doi.org/10.1093/nar/gkw1005
Autor:
Sijia Wu, Karl D. Bellve, Haley E. Melikian, Clive Standley, Luke R. Gabriel, Patrick J. Kearney, Kevin E. Fogarty
Publikováno v:
The Journal of Neuroscience. 33:17836-17846
Dopaminergic signaling profoundly impacts rewarding behaviors, movement, and executive function. The presynaptic dopamine (DA) transporter (DAT) recaptures released DA, thereby limiting synaptic DA availability and maintaining dopaminergic tone. DAT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3440659f7b7d30b273ca7cad418e5ef0
https://doi.org/10.1523/jneurosci.3284-13.2013
https://doi.org/10.1523/jneurosci.3284-13.2013
Publikováno v:
Molecular and Cellular Neuroscience. 50:82-92
In addition to its role as a morphogen, Sonic hedgehog (Shh) has also been shown to function as a guidance factor that directly acts on the growth cones of various types of axons. However, the noncanonical signaling pathways that mediate the guidance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47376f0b9d0d332d3f025febb245491c
https://doi.org/10.1016/j.mcn.2012.03.008
https://doi.org/10.1016/j.mcn.2012.03.008
Publikováno v:
Archives of Pathology & Laboratory Medicine. 135:255-263
Context.—Advances in microscopy enable visualization of a broad range of new morphologic features. Objective.—To review and illustrate advances in microscopy with relevance to pathologists. Data Sources.—Literature review and new observations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166a73fc1ff42b3763daddda18de945a
https://doi.org/10.5858/135.2.255
https://doi.org/10.5858/135.2.255
Autor:
Nathan D. Lawson, Adam Hurlstone, Clive Standley, Stefania Nicoli, Kevin E. Fogarty, Paul Walker
Publikováno v:
Nature. 464:1196-1200
Within the circulatory system, blood flow regulates vascular remodelling, stimulates blood stem cell formation, and has a role in the pathology of vascular disease. During vertebrate embryogenesis, vascular patterning is initially guided by conserved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::501db391df63ff9ee86a1cb4d3c9b75a
https://doi.org/10.1038/nature08889
https://doi.org/10.1038/nature08889
Autor:
Adrianne L. Kolpak, Clive Standley, Jun Jiang, Karl D. Bellve, Zheng-Zheng Bao, Daorong Guo, Kevin E. Fogarty
Publikováno v:
The Journal of Neuroscience. 29:10488-10498
Macropinocytosis is a type of poorly characterized fluid-phase endocytosis that results in formation of relatively large vesicles. We report that Sonic hedgehog (Shh) protein induces macropinocytosis in the axons through activation of a noncanonical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a0c645651f8c8233db6469625249ea1
https://doi.org/10.1523/jneurosci.2355-09.2009
https://doi.org/10.1523/jneurosci.2355-09.2009
Autor:
Silvia Corvera, Akira Hayakawa, Stephanie T. Murphy, Karl D. Bellve, Martha C. Soto, Clive Standley, Kevin E. Fogarty, Deborah M. Leonard, Susan J. Hayes, Craig C. Mello, David G. Lambright
Publikováno v:
Proceedings of the National Academy of Sciences. 103:11928-11933
The FYVE domain binds with high specificity and avidity to phosphatidylinositol 3-phosphate. It is present in ≈30 proteins in humans, some of which have been implicated in functions ranging from early endosome fusion to signal transduction through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1182c95721a1a56a9a2086ba58959b1c
https://doi.org/10.1073/pnas.0508832103
https://doi.org/10.1073/pnas.0508832103
Autor:
Richard A. Tuft, Karl D. Bellve, Kevin E. Fogarty, Akira Hayakawa, Silvia Corvera, Lawrence M. Lifshitz, Clive Standley, Deborah M. Leonard
Publikováno v:
Journal of Biological Chemistry. 281:16139-16146
Clathrin assembly at the plasma membrane is a fundamental process required for endocytosis. In cultured cells, most of the clathrin is localized to large patches that display little lateral mobility. The functional role of these regions is not clear,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c86b9998dd344804d1f8269f2898d7
https://doi.org/10.1074/jbc.m511370200
https://doi.org/10.1074/jbc.m511370200