Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Clive R. Wood"'
Autor:
Clive R Wood
Monoclonal antibodies have become important treatments for cancer, inflammation and a wide range of other diseases, representing an increasing share of the most successful pharmaceutical markets. The technologies to discover these drugs have been dev
Autor:
Daniel T. Dransfield, Clive R. Wood, Maria Luisa Valentino, Shafaat A. Rabbani, Chris TenHoor, Paula Henderikx, Rene Hoet, Robert C. Ladner, Andrew E. Nixon, Sonia Schoonbroodt, Yu Lu Ma, Csaba Pazmany, Shannon Hogan, Douglas Rank, Guannan Kuang, Daniel J. Sexton, Reinoud van Gool, Annabelle Lejeune, Marc Vanhove, Qingfeng Tao, Edward Chang, Nicolas Frans, Henk Pieters, Niranjan Yanamandra, Laurent Naa, Lili Huang, Laetitia Devy
Inhibition of specific matrix metalloproteinases (MMP) is an attractive noncytotoxic approach to cancer therapy. MMP-14, a membrane-bound zinc endopeptidase, has been proposed to play a central role in tumor growth, invasion, and neovascularization.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ad90f85bac4e1357eb214667eadf37f
https://doi.org/10.1158/0008-5472.c.6499896.v1
https://doi.org/10.1158/0008-5472.c.6499896.v1
Autor:
Daniel T. Dransfield, Clive R. Wood, Maria Luisa Valentino, Shafaat A. Rabbani, Chris TenHoor, Paula Henderikx, Rene Hoet, Robert C. Ladner, Andrew E. Nixon, Sonia Schoonbroodt, Yu Lu Ma, Csaba Pazmany, Shannon Hogan, Douglas Rank, Guannan Kuang, Daniel J. Sexton, Reinoud van Gool, Annabelle Lejeune, Marc Vanhove, Qingfeng Tao, Edward Chang, Nicolas Frans, Henk Pieters, Niranjan Yanamandra, Laurent Naa, Lili Huang, Laetitia Devy
Supplementary Methods and Materials from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362235aff74f4e94e6209bb11bdd0a07
https://doi.org/10.1158/0008-5472.22381518.v1
https://doi.org/10.1158/0008-5472.22381518.v1
Autor:
Daniel T. Dransfield, Clive R. Wood, Maria Luisa Valentino, Shafaat A. Rabbani, Chris TenHoor, Paula Henderikx, Rene Hoet, Robert C. Ladner, Andrew E. Nixon, Sonia Schoonbroodt, Yu Lu Ma, Csaba Pazmany, Shannon Hogan, Douglas Rank, Guannan Kuang, Daniel J. Sexton, Reinoud van Gool, Annabelle Lejeune, Marc Vanhove, Qingfeng Tao, Edward Chang, Nicolas Frans, Henk Pieters, Niranjan Yanamandra, Laurent Naa, Lili Huang, Laetitia Devy
Supplementary Tables1-2 from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202e975447b6fb0d17af004056b1b698
https://doi.org/10.1158/0008-5472.22381515
https://doi.org/10.1158/0008-5472.22381515
Autor:
Andreas Gollner, Markus Köster, Paul Nicklin, Thomas Trieselmann, Elliott Klein, Jaromir Vlach, Claudia Heine, Marc Grundl, Jürgen Ramharter, David Wyatt, Menorca Chaturvedi, Alessio Ciulli, Katharine C. Carter, Susanne Müller, Daniel Bischoff, Peter Ettmayer, Eric Haaksma, Jürgen Mack, Darryl McConnell, Dirk Stenkamp, Harald Weinstabl, Matthias Zentgraf, Clive R. Wood, Florian Montel
Publikováno v:
Nature reviews. Drug discovery. 21(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0532092410ea682f9e1120d72a6dd5c
https://pubmed.ncbi.nlm.nih.gov/35459938
https://pubmed.ncbi.nlm.nih.gov/35459938
Autor:
Andrew E Nixon, Jie eChen, Daniel J Sexton, Arumugam eMuruganandam, Alan J Bitonti, Jennifer eDumont, Malini eViswanathan, Diana eMartik, Dina eWassaf, Adam eMezo, Clive R Wood, Joseph C Biedenkapp, Christopher eTenHoor
Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
The therapeutic management of antibody mediated autoimmune disease typically involves immunosuppressant and immunomodulatory strategies. However, perturbing the fundamental role of the neonatal Fc receptor (FcRn) in salvaging IgG from lysosomal degra
Externí odkaz:
https://doaj.org/article/93695677b70b4ff8a92947f67b2596cb
Autor:
Jurate Garbaraviciene, Thierry Calandra, Gerhard Antoine, Didier Le Roy, Wolf-Henning Boehncke, Michael Thiele, Clive R. Wood, Hartmut J. Ehrlich, Randolf Kerschbaumer, Thierry Roger, Manfred Rieger, Dirk Völkel, Jürgen Müllberg, Rene Hoet, Michael Dockal, Friedrich Scheiflinger, Helga Savidis-Dacho
Publikováno v:
The Journal of biological chemistry
JOURNAL OF BIOLOGICAL CHEMISTRY
Journal of Biological Chemistry, Vol. 287, No 10 (2012) pp. 7446-7455
JOURNAL OF BIOLOGICAL CHEMISTRY
Journal of Biological Chemistry, Vol. 287, No 10 (2012) pp. 7446-7455
The macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine that recently emerged as an attractive therapeutic target for a variety of diseases. A diverse panel of fully human anti-MIF antibodies was generated by selection from a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd75e6ea654d84e80bd66d12ab78738a
https://doi.org/10.1074/jbc.m111.329664
https://doi.org/10.1074/jbc.m111.329664
Autor:
Clive R Wood
Publikováno v:
Antibody Drug Discovery. :441-473
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf2e59825a1de881a34e5770bfeb62b6
https://doi.org/10.1142/9781848166295_bmatter
https://doi.org/10.1142/9781848166295_bmatter
Autor:
Clive R Wood
Publikováno v:
Antibody Drug Discovery. :i-xv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::502a476dad7c7f82009196e27730fdd8
https://doi.org/10.1142/9781848166295_fmatter
https://doi.org/10.1142/9781848166295_fmatter
Autor:
Jie Chen, Dina Wassaf, Malini Viswanathan, Diana Martik, Clive R. Wood, Chris TenHoor, Andrew E. Nixon, Joseph C. Biedenkapp, Daniel J. Sexton, Jennifer A. Dumont, Adam R. Mezo, Arumugam Muruganandam, Alan J. Bitonti
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 6 (2015)
Frontiers in Immunology, Vol 6 (2015)
The therapeutic management of antibody mediated autoimmune disease typically involves immunosuppressant and immunomodulatory strategies. However, perturbing the fundamental role of the neonatal Fc receptor (FcRn) in salvaging IgG from lysosomal degra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89fdfc63ac3b5db58b466204f898d483
http://europepmc.org/articles/PMC4407741
http://europepmc.org/articles/PMC4407741