Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Clive Patience"'
Publikováno v:
Xenotransplantation. 16:239-248
Xenotransplantation using porcine cells, tissues, or organs may offer a potential solution for the shortage of allogeneic human organs. Prior to the clinical use of porcine xenotransplants, three main hurdles must be overcome: immunologic rejection,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::839d9824c30419791de8345f0775fbe2
https://doi.org/10.1111/j.1399-3089.2009.00544.x
https://doi.org/10.1111/j.1399-3089.2009.00544.x
Autor:
Clive Patience
Publikováno v:
Current Opinion in Organ Transplantation. 10:334-337
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93d9ff7a4fba45a9e455a4dfcd6d3068
https://doi.org/10.1097/01.mot.0000184015.08703.b2
https://doi.org/10.1097/01.mot.0000184015.08703.b2
Autor:
M. Przemeck, R Lorenz, Jens Hecker, Michael Winkler, SP Sommer, Monica E. Winkler, Ulrich Martin, Rosemarie Burian, M Loss, Clive Patience, Joachim Denner, Alexander Karlas
Publikováno v:
Transplant International. 17:848-858
Clinical pig-to-human xenotransplantation might be associated with the risk of transmission of xenozoonoses, especially porcine endogenous retroviruses (PERVs). We have established a pig-to-humanised-cynomolgus monkey xenotransplantation model allowi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3babf7e811448ab5a5d243df0d4c1838
https://doi.org/10.1111/j.1432-2277.2004.tb00520.x
https://doi.org/10.1111/j.1432-2277.2004.tb00520.x
Autor:
Jay A. Fishman, Clive Patience
Publikováno v:
American Journal of Transplantation
Xenotransplantation is a possible solution for the shortage of tissues for human transplantation. Multiple hurdles exist to clinical xenotransplantation, including immunologic barriers, metabolic differences between pigs – the source species most c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac236630e742fdb78e9434f2df34b99
https://doi.org/10.1111/j.1600-6143.2004.00542.x
https://doi.org/10.1111/j.1600-6143.2004.00542.x
Autor:
Jay A. Fishman, Megan Sykes, Yong-Guang Yang, Clive Patience, Robert A. Wilkinson, Ping Lan, James Wood
Publikováno v:
Journal of Clinical Investigation. 114:695-700
Porcine endogenous retrovirus (PERV) is a potential pathogen in clinical xenotransplantation; transmission of PERV in vivo has been suggested in murine xenotransplantation models. We analyzed the transmission of PERV to human cells in vivo using a mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eac4b97a4179fe7ab70dac44c974d1d
https://doi.org/10.1172/jci21946
https://doi.org/10.1172/jci21946
Autor:
David M. Neville, Rebecca C. Coburn, David H. Sachs, Clive Patience, Jay A. Fishman, Robert A. Cina, Elizabeth Melendy, Nicolas J. Mueller, Shehan Hettiaratchy, Patricia S. Cho, Christene A. Huang, Andrew M. Cameron
Publikováno v:
American Journal of Transplantation. 4:1274-1282
A high incidence of a post-transplant lymphoproliferative disorder (PTLD) is observed in miniature swine conditioned for allogeneic hematopoietic cell transplantation using a protocol involving T-cell depletion and cyclosporine therapy. This study wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::968c2e9d444fbfde48ade89ae2af4a52
https://doi.org/10.1111/j.1600-6143.2004.00506.x
https://doi.org/10.1111/j.1600-6143.2004.00506.x
Autor:
Gillian Langford, Clive Patience, Saema Magre, Andrew Richards, Robin A. Weiss, Yasuhiro Takeuchi
Publikováno v:
Journal of Virology. 78:5812-5819
Complement activation mediated by the major xenogeneic epitope in the pig, galactosyl-α(1-3) galactosyl sugar structure (α-Gal), and human natural antibodies could cause hyperacute rejection (HAR) in pig-to-human xenotransplantation. The same react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94b65c15329d3ec927ef4c4a1bdd746
https://doi.org/10.1128/jvi.78.11.5812-5819.2004
https://doi.org/10.1128/jvi.78.11.5812-5819.2004
Autor:
Jonathan P. Stoye, Clive Patience
Publikováno v:
Current Opinion in Organ Transplantation. 9:176-180
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab6ee8c819838463a9ee87e664cd07b7
https://doi.org/10.1097/01.mot.0000125489.13679.84
https://doi.org/10.1097/01.mot.0000125489.13679.84
Autor:
Maria Denaro, Peter B. Morgan, Clive Patience, Angela Sullivan, Stuart L. Houser, Kevin W. Johnson, Mary E. White-Scharf, Julian D. Down, Göran Andersson
Publikováno v:
Molecular Therapy. 8(3):385-391
We have investigated whether a state of tolerance toward EGFP-expressing skin tissue can be induced by prior establishment of EGFP molecular chimerism by transplant of gene-transduced bone marrow in mice. Irradiated (10 Gy) C57BL/6J mice were transpl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1118934af2b5dd525eb00d545bd8b690
Autor:
Y. Xu, Clive Patience, R. Bower, G. Quinn, Maria A. Giovino, Henk-Jan Schuurman, G. Dos-Santos Cruz
Publikováno v:
European Journal of Immunogenetics. 30:259-270
The MHC class II transactivator, CIITA, is critical for MHC class II gene expression in all species studied to date. We isolated an interferon (IFN)-gamma-inducible isoform of porcine CIITA (pCIITA') encoding a protein of 566 amino acids (aa) with si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2323508cae4e7c896192ddb7e05f1e46
https://doi.org/10.1046/j.1365-2370.2003.00397.x
https://doi.org/10.1046/j.1365-2370.2003.00397.x