Zobrazeno 1 - 10
of 561
pro vyhledávání: '"Clive P, Page"'
Autor:
Mario Cazzola, Clive P. Page, Jadwiga A. Wedzicha, Bartolome R. Celli, Antonio Anzueto, Maria Gabriella Matera
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Oxidative stress and persistent airway inflammation are thought to be important contributors to the development of chronic obstructive pulmonary disease (COPD). This review summarizes the evidence for targeting oxidative stress an
Externí odkaz:
https://doaj.org/article/6bba8031d0d8401ab5e9891c5158f396
Autor:
Daiana Stolz, Maria Gabriella Matera, Paola Rogliani, Maarten van den Berge, Eleni Papakonstantinou, Reinoud Gosens, Dave Singh, Nicola Hanania, Mario Cazzola, Anke-Hilse Maitland-van der Zee, Laura Fregonese, Alexander G. Mathioudakis, Jørgen Vestbo, Maia Rukhadze, Clive P. Page
Publikováno v:
Breathe, Vol 19, Iss 2 (2023)
Pharmacological management of airway obstructive diseases is a fast-evolving field. Several advances in unravelling disease mechanisms as well as intracellular and molecular pathways of drug action have been accomplished. While the clinical translati
Externí odkaz:
https://doaj.org/article/d318550bc22949b8b4e3a6be9a3c1560
Autor:
Jon Petur Joelsson, Jennifer A. Kricker, Ari J. Arason, Snaevar Sigurdsson, Bryndis Valdimarsdottir, Fridrik Runar Gardarsson, Clive P. Page, Fredrik Lehmann, Thorarinn Gudjonsson, Saevar Ingthorsson
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background The airway epithelium (AE) forms the first line of defence against harmful particles and pathogens. Barrier failure of the airway epithelium contributes to exacerbations of a range of lung diseases that are commonly treated with A
Externí odkaz:
https://doaj.org/article/68af876a3a5d4feaab0da207655852e8
Autor:
Ari Jon Arason, Jon Petur Joelsson, Bryndis Valdimarsdottir, Snaevar Sigurdsson, Alexander Gudjonsson, Skarphedinn Halldorsson, Freyr Johannsson, Ottar Rolfsson, Fredrik Lehmann, Saevar Ingthorsson, Paulina Cherek, Gudmundur H. Gudmundsson, Fridrik R. Gardarsson, Clive P. Page, Olafur Baldursson, Thorarinn Gudjonsson, Jennifer A. Kricker
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-19 (2019)
Abstract Background Azithromycin (Azm) is a macrolide recognized for its disease-modifying effects and reduction in exacerbation of chronic airway diseases. It is not clear whether the beneficial effects of Azm are due to its anti-microbial activity
Externí odkaz:
https://doaj.org/article/c8da4be92fa246189c8660fe3fd024d1
Publikováno v:
Methods and Protocols, Vol 5, Iss 5, p 71 (2022)
Platelet–neutrophil complexes (PNCs) occur during the inflammatory response to trauma and infections, and their interactions enable cell activation that can lead to tissue destruction. The ability to identify the accumulation and tissue localisatio
Externí odkaz:
https://doaj.org/article/9c00749d533c4c3da499d3b24a5b9a23
A rapid increase in our understanding of the biology of platelets and their role in disease in recent years has been paralleled by increasing successes with established platelet-modifying therapies in many clinical conditions. This text focuses on th
Publikováno v:
Pharmacological Reviews. 75:328-379
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1036500a36d843f47920463e8c65a719
https://doi.org/10.1124/pharmrev.122.000684
https://doi.org/10.1124/pharmrev.122.000684
Autor:
Simon J. Cleary, Clive P. Page
Publikováno v:
Platelets, Vol 29, Iss 8, Pp 766-770 (2018)
Gustav Born achieved scientific fame for his application of light transmission aggregometry to the study of platelet function, but also led interdisciplinary research teams in pioneering quantitative in vivo imaging studies of platelet aggregation an
Externí odkaz:
https://doaj.org/article/95cb95227e654a04a4d70f2efdf525ab
Autor:
Mario Cazzola, Paola Rogliani, Peter J Barnes, Francesco Blasi, Bartolome Celli, Nicola A Hanania, Fernando J. Martinez, Bruce E Miller, Marc Miravitlles, Clive P. Page, Ruth Tal-Singer, Maria Gabriella Matera
Publikováno v:
American Journal of Respiratory and Critical Care Medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db173a68f047ec10c6bbcc270923f520
https://doi.org/10.1164/rccm.202303-0400so
https://doi.org/10.1164/rccm.202303-0400so
Autor:
Kate L. Arkless, Dingxin Pan, Manu Shankar‐Hari, Richard T. Amison, Clive P. Page, Khondaker Miraz Rahman, Simon C. Pitchford
Publikováno v:
Arkless, K L, Pan, D, Shankar-hari, M, Amison, R T, Page, C P, Rahman, K M & Pitchford, S C 2023, ' Stimulation of platelet P2Y1 receptors by different endogenous nucleotides leads to functional selectivity via biased signalling ', British Journal of Pharmacology . https://doi.org/10.1111/bph.16039
Background and Purpose: Platelet function during inflammation is dependent on activation by endogenous nucleotides. Non-canonical signalling via the P2Y1 receptor is important for these non- thrombotic functions of platelets. However, apart from ADP,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c093c800159c98eafc03d577e49fb3f
https://www.pure.ed.ac.uk/ws/files/327113649/Published_Version.pdf
https://www.pure.ed.ac.uk/ws/files/327113649/Published_Version.pdf