Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Clive Meredith"'
Publikováno v:
Toxicology Reports, Vol 6, Iss , Pp 1155-1163 (2019)
The in vitro mutagenic and genotoxic potential of Heated Tobacco Products (HTPs) has already been studied with the particulate phase and reported previously. This study has been designed to complement the in vitro assessment of the HTP and to determi
Externí odkaz:
https://doaj.org/article/373cf36cb19b4fc286fda9e2d0a7267a
Publikováno v:
Toxicology Reports, Vol 6, Iss, Pp 1155-1163 (2019)
Toxicology Reports
Toxicology Reports
The in vitro mutagenic and genotoxic potential of Heated Tobacco Products (HTPs) has already been studied with the particulate phase and reported previously. This study has been designed to complement the in vitro assessment of the HTP and to determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80de019cc17be3d2cc50fdaaf8cef520
http://www.sciencedirect.com/science/article/pii/S221475001930280X
http://www.sciencedirect.com/science/article/pii/S221475001930280X
Autor:
Joanne Kilford, Debbie Dillon, Mark Ballantyne, Julie Clements, Annette Dalrymple, Marianna Gaҫa, M. Hollings, David Thorne, Clive Meredith, Rebecca Payne
Publikováno v:
Mutation research. Genetic toxicology and environmental mutagenesis.
This work investigates a completely novel and experimental concept of exposing L5178Y cells at the air-agar-interface to mainstream cigarette smoke aerosol (Kentucky reference 3R4F). This study highlights the associated challenges of combining a susp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d76eedc32f25dbe17e7a25aa9679d5c
https://pubmed.ncbi.nlm.nih.gov/32928375
https://pubmed.ncbi.nlm.nih.gov/32928375
Autor:
Stephen Clive Meredith
With merit now considered a positive and essential route to social progress and reward, the article considers the origins and emergence of the concept as largely a perjorative dimension of social democratic discourses of equality in the 1950s, and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad22795f074c90bf09f5be3f5476b40
Autor:
Clive Meredith, Louise Neilson, Christopher Proctor, Tobi Oke, Kevin McAdam, Ken Scott, Ian Crooks, Mark Forster, Lorna Reynolds
Publikováno v:
Food and Chemical Toxicology. 118:940-952
We designed a novel tobacco-heating product (THP) that heats tobacco to release nicotine and aerosolised components, such as glycerol and tobacco volatiles from a tobacco rod (Neostik). Heating tobacco significantly reduces levels of combustion-deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa51d39aab81d15fcef5304a39a30963
https://doi.org/10.1016/j.fct.2018.05.058
https://doi.org/10.1016/j.fct.2018.05.058
Publikováno v:
Regulatory Toxicology and Pharmacology. 95:102-114
The concept of a risk continuum for tobacco and nicotine products has been proposed, which differentiates products according to their propensity to reduce toxicant exposure and risk. Cigarettes are deemed the most risky and medicinal nicotine the lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c8018f3689df6f121b8d3b18ba94a0a
https://doi.org/10.1016/j.yrtph.2018.03.005
https://doi.org/10.1016/j.yrtph.2018.03.005
Autor:
Clive Meredith, Stacy Fiebelkorn
Publikováno v:
Risk Analysis. 38:1490-1501
Several epidemiological studies have demonstrated an association between occupational benzene exposure and increased leukemia risk, in particular acute myeloid leukemia (AML). However, there is still uncertainty as to the risk to the general populati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d65429262ff4d0ad4a2a0f1a12f865a
https://doi.org/10.1111/risa.12956
https://doi.org/10.1111/risa.12956
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 812:29-38
Salmonella typhimurium strains TA98 and TA100 were used to assess the mutagenic potential of the aerosol from a commercially available, rechargeable, closed system electronic-cigarette. Results obtained were compared to those for the mainstream smoke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba0477cb902c3fcbeab4522cc5b19d38
Autor:
Harvey J. Clewell, Clive Meredith, Allison Franzen, Susan Crowell, Robinan Gentry, Jerry L. Campbell, Anne Loccisano, Cynthia Van Landingham, Michael Lumpkin
Publikováno v:
Inhalation Toxicology
Benzo[a]pyrene (BaP) is a by-product of incomplete combustion of fossil fuels and plant/wood products, including tobacco. A physiologically based pharmacokinetic (PBPK) model for BaP for the rat was extended to simulate inhalation exposures to BaP in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8cdd30406564745164041e69a369303
http://europepmc.org/articles/PMC5020340
http://europepmc.org/articles/PMC5020340
Autor:
Louise Neilson, Courtney Mankus, David Thorne, Clive Meredith, George R. Jackson, Jason DeBay
Publikováno v:
Toxicology in Vitro. 29:1952-1962
Development of physiologically relevant test methods to analyse potential irritant effects to the respiratory tract caused by e-cigarette aerosols is required. This paper reports the method development and optimisation of an acute in vitro MTT cytoto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47098ace480e29511b8ad93a1a67c658
https://doi.org/10.1016/j.tiv.2015.05.018
https://doi.org/10.1016/j.tiv.2015.05.018