Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Clive M. Baumgarten"'
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0127936 (2015)
Nicotine elicits bitter taste by activating TRPM5-dependent and TRPM5-independent but neuronal nAChR-dependent pathways. The nAChRs represent common targets at which acetylcholine, nicotine and ethanol functionally interact in the central nervous sys
Externí odkaz:
https://doaj.org/article/6b09195c07344805a2bd43fc82bcbd31
Publikováno v:
British Journal of Pharmacology. 175:3422-3432
Background and purpose Adrenergic regulation of cell volume-regulated chloride current (ICl.vol ) is species-dependent. The present study investigates the mechanism underlying adrenergic regulation of ICl.vol in human atrial myocytes. Experimental ap
Autor:
Xulin Xu, Min Jiang, Yuhong Wang, Timothy Smith, Clive M Baumgarten, Mark A Wood, Gea-Ny Tseng
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10140 (2010)
Clinical trials and epidemiological studies have suggested that dietary fish oil (FO) supplementation can provide an anti-arrhythmic benefit in some patient populations. The underlying mechanisms are not entirely clear. We wanted to understand how FO
Externí odkaz:
https://doaj.org/article/3a7f80e401144821863e6e870c5f6511
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 468:817-824
Inwardly rectifying K(+) (Kir) channels are important contributors to the resting membrane potential and regulate cellular excitability. The activity of Kir channels depends critically on the phospholipid PIP2. Several modulators of the activity of K
Autor:
Namrata Tiwari, John R. Grider, Shanwei Shen, Clive M. Baumgarten, Jonathan E. Madar, Li-Ya Qiao
Publikováno v:
Gastroenterology. 158:S-72
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Accumulation of cholesterol loaded macrophage foam cells is the hallmark of atherosclerotic lesions where high cellular cholesterol content not only contributes to the plaque volume but is also responsible for the inflammatory milieu. Causal relation
Publikováno v:
British journal of pharmacology. 175(16)
BACKGROUND AND PURPOSE: Adrenergic regulation of cell volume‐regulated chloride current (I(Cl.vol)) is species‐dependent. The present study investigates the mechanism underlying adrenergic regulation of I(Cl.vol) in human atrial myocytes. EXPERIM
Publikováno v:
Cardiovascular Research. 88:93-100
We assessed regulation of volume-sensitive Cl(-) current (I(Cl,swell)) by endothelin-1 (ET-1) and characterized the signalling pathway responsible for its activation in rabbit atrial and ventricular myocytes.ET-1 elicited I(Cl,swell) under isosmotic
Autor:
Zuojun Ren, Clive M. Baumgarten
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 288:H2628-H2636
Regulation of swelling-activated Cl−current ( ICl,swell) is complex, and multiple signaling cascades are implicated. To determine whether protein tyrosine kinase (PTK) modulates ICl,swelland to identify the PTK involved, we studied the effects of a
Autor:
Zhan Gao, Shui-Wah Chiu, Gui-Rong Li, Hung-Fat Tse, Chu-Pak Lau, Xin-Ling Du, Clive M. Baumgarten
Publikováno v:
The Journal of General Physiology
To determine whether protein tyrosine kinase (PTK) modulates volume-sensitive chloride current (I(Cl.vol)) in human atrial myocytes and to identify the PTKs involved, we studied the effects of broad-spectrum and selective PTK inhibitors and the prote