Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Clive Hayward"'
Autor:
Maria Suprun, Paul Kearney, Clive Hayward, Heather Butler, Robert Getts, Scott H. Sicherer, Paul J. Turner, Dianne E. Campbell, Hugh A. Sampson
Publikováno v:
Allergy. 77:3061-3069
Background: IgE-epitope profiling can accurately diagnose clinical peanut allergy. Objective: We sought to determine whether sequential (linear) epitope-specific IgE (ses-IgE) profiling can provide probabilities of tolerating discrete doses of peanut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::040246e30218f4d044ab8b114f2640d3
https://doi.org/10.1111/all.15477
https://doi.org/10.1111/all.15477
Autor:
Alex Porter, Stephen J. Galli, Kari C. Nadeau, Paul Kearney, Maria Suprun, Mayte Suárez-Fariñas, Clive Hayward, Galina Grishina, Marc Witmer, Hugh A. Sampson, Gideon Lack, Robert C. Getts, George Du Toit, Rebecca S. Chinthrajah, David Luta
Publikováno v:
Allergy. 76:3789-3797
Background Accurate diagnosis of peanut allergy is a significant clinical challenge. Here, a novel diagnostic blood test using the peanut bead-based epitope assay ("peanut BBEA") was developed utilizing the LEAP cohort and then validated using two in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5fef48135b833a2d713af48e3326a7
https://doi.org/10.1111/all.14905
https://doi.org/10.1111/all.14905
Autor:
Marc Witmer, Paul Kearney, Stephen J. Galli, Gideon Lack, David Luta, Hugh A. Sampson, Galina Grishina, Kari C. Nadeau, R. Sharon Chinthrajah, Alex Porter, Mayte Suárez-Fariñas, Robert C. Getts, Clive Hayward, George Du Toit, Maria Suprun
BackgroundMisdiagnosis of peanut allergy is a significant clinical challenge. Here, a novel diagnostic blood-based test using a Bead-Based Epitope Assay (“peanut BBEA”) has been developed on the LEAP cohort and then independently validated on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eadd552864ebf026bffb5b0a37f3615
https://doi.org/10.1101/2020.06.19.20136002
https://doi.org/10.1101/2020.06.19.20136002
Autor:
Xiao-Jun Li, Anil Vachani, Peter J. Mazzone, Clive Hayward, David E. Midthun, William N. Rom, Harvey I. Pass, Pui Yee Fong, Michel Laviolette, Jing Shi, Pierre P. Massion, Stephen W. Hunsucker, Paul Kearney, Eric S. Edell, Kenneth C. Fang, David K. Madtes, Michael G. Walker, York E. Miller
Publikováno v:
Journal of Thoracic Oncology
Introduction Indeterminate pulmonary nodules (IPNs) lack clinical or radiographic features of benign etiologies and often undergo invasive procedures unnecessarily, suggesting potential roles for diagnostic adjuncts using molecular biomarkers. The pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fef0f845f418e20e7eaa4b0dfa32c2b0
Autor:
JoAnne Mulligan, Pui-Yee Fong, Kenneth C. Fang, Mi-Youn Brusniak, Douglas A. Spicer, Xiao-Jun Li, Matthew McLean, Paul Kearney, Stephen W. Hunsucker, Lik Wee Lee, Clive Hayward
Publikováno v:
Clinical Proteomics
Background Current quantification methods for mass spectrometry (MS)-based proteomics either do not provide sufficient control of variability or are difficult to implement for routine clinical testing. Results We present here an integrated quantifica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785d73b8da3659a891380fab6cad349d
http://europepmc.org/articles/PMC4363461
http://europepmc.org/articles/PMC4363461
Autor:
Olivier Gingras, Anil Vachani, William N. Rom, Rene Allard, Pui Yee Fong, Leroy Hood, Paul Kearney, Scott M. Law, Heather Butler, Pierre P. Massion, Julie Lamontagne, Nathan D. Price, Stephen W. Hunsucker, Xiao-Jun Li, Daniel Chelsky, Michael Schirm, Michel Dominguez, Kenneth C. Fang, Harvey I. Pass, Stephen Lam, Lik Wee Lee, Clive Hayward, Matthew McLean
Publikováno v:
Science translational medicine. 5(207)
Each year, millions of pulmonary nodules are discovered by computed tomography and subsequently biopsied. Because most of these nodules are benign, many patients undergo unnecessary and costly invasive procedures. We present a 13-protein blood-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a2adc888b1968183e3c2c0c7b2ab74
https://pubmed.ncbi.nlm.nih.gov/24132637
https://pubmed.ncbi.nlm.nih.gov/24132637
Autor:
Kevin Eng, Dmitri Sitnikov, Gregory J. Opiteck, Clive Hayward, Paul Kearney, Isabelle Migneault, Sylvain Tessier, Joanna M. Hunter
Publikováno v:
Journal of the American Society for Mass Spectrometry. 18(9)
Chromatographic protein and peptide separation technologies enable comprehensive proteomic analysis of plasma and other complex biological samples by mass spectrometry. However, as the number of separations and/or fractions increases, so does the num
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3f77734c9a904ed9326aeedb60aa9a
https://pubmed.ncbi.nlm.nih.gov/17689095
https://pubmed.ncbi.nlm.nih.gov/17689095
Autor:
Marc Pinard, Andrew J. Dorner, Eustache Paramithiotis, Lili Wang, Maximillian T. Follettie, Heather A. Harris, Pierre Thibault, Paul Kearney, Clive Hayward, Daniel Chelsky, James C. Keith
Publikováno v:
Endocrinology. 147(2)
Two receptors [estrogen receptor (ER)alpha and ERbeta] mediate the manifold effects of estrogens throughout the body. Although a clear role has been established for ERalpha in the classical effects of estrogen activity, the physiological role of ERbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebaea2ddfd5858784027315ec9fd0f2d
https://pubmed.ncbi.nlm.nih.gov/16269464
https://pubmed.ncbi.nlm.nih.gov/16269464