HER2-enriched subtype and novel molecular subgroups drive aromatase inhibitor resistance and an increased risk of relapse in early ER+/HER2+ breast cancer

Autor: Milana A. Bergamino, Elena López-Knowles, Gabriele Morani, Holly Tovey, Lucy Kilburn, Eugene F. Schuster, Anastasia Alataki, Margaret Hills, Hui Xiao, Chris Holcombe, Anthony Skene, John F. Robertson, Ian E. Smith, Judith M. Bliss, Mitch Dowsett, Maggie C.U. Cheang, Abigail Evans, Adrian Ball, Akhil Johri, Ali Nejim, Alison Jones, Allan Corder, Amanda Thorne, Ambika Anand, Amitabha Chakrabarti, Anne Robinson, Anupam Modi, Ashraf Patel, Ashutosh Kothari, Brendan McFall, Caroline Mortimer, Caroline Lee, Charlie Chan, Charlotte Abson, Christopher Holcombe, Christopher Hinton, Ciaran Hollywood, Claire Murphy, Clare Crowley, Claudia Harding-Mackean, Clive Griffith, Conrad Lewanski, Daniel Rea, David Hwang, Derek Crawford, Dinesh Thekkinkattil, Douglas Ferguson, Douglas Adamson, Duncan Wheatley, Duraisamy Ravichandran, Ed Babu, Elaine Hyett, Fawzia Ashkanani, Fiona Hoar, Frances Kenny, Gary Dyke, Geoffrey Sparrow, null Gilbert, Giles Cunnick, Hafiz Algurafi, Helen Sweetland, Highes-Davies Prof, Hisham Hamed, Ian Smith, Ian Laidlaw, Ilyas Khattak, Jacqueline Newby, Jacqueline Rees-Lee, Jalal Kokan, Jane Barrett, Jay Dolatrai Naik, Jayant Vaidya, Jennifer Forrest, Jitendra Parmar, Jocelyn Adams, John Fox, Jonathan Roberts, Jonathan Dawson, Julie Doughty, Jull Donnelly, Kathleen Dunn, Kian Chin, Kieran Horgan, Kislaya Thakur, Ludger Barthelmes, Lynda Wyld, Madhumita Bhattacharyya, Maher Hadaki, Makam Kishore, Marcus Ornstein, Maria Bramley, Maria Bews-Hair, Marina Parton, Mark Sibbering, Mark Kissin, Mark Churn, Martin Hogg, Mary Quigley, Matthew Hatton, Matthew Winter, Matthew Adelekan, Michael Shere, Michael Carr, Michael Williams, Mohammed Absar, Muhammad Sharif, Muireann Kelleher, Nawaz Walji, Nicholas Williams, Nicholas Gallegos, Nigel Bundred, Olivia Hatcher, Perric Crellin, Peter Crane, Peter Donnelly, Peter Kneeshaw, Philip Walker, Prakash Sinha, Pudhupalayam Bhaskar, Racheal Soulsby, Radha Todd, Raghavan Vidya, Rakesh Mehra, Ramachandran Prasad, Ramsay Cutress, Ravi Sharma, Rebecca Roylance, Rebecca Goranova, Reem Ramzi Salman, Riccardo Bonom, Richard Johnson, Richard Sutton, Rick Linforth, Rob Coleman, Robert Grieve, Robert Leonard, Robert Reichert, Robert Kennedy, Roshan Agarwal, Rozenn Allerton, Russell Burcombe, Ruth Davis, Sankaran Narayanan, Sankaran Chandrasekharan, Sarah Vesty, Seema Seetharam, Serena Ledwidge, Shabana Iqbal, Shamaela Wahee, Shobha Silva, Simon Pain, Simon Holt, Simon Thomson, Simon Smith, Simon Ellenbogen, Siobhan Laws, Stephen Chan, Stephen Johnston, Steve Holt, Steven Thrush, Stuart McIntosh, Sumohan Chatterjee, Susan Cleator, Tamoor Usman, Tayo Johnson, Tibor Kovacs, Tracey Irvine, Urmila Barthkur, Vanessa Pope, Victoria Alexandra Brown, Vummiti Muralikrishna, Walid Samra, William Maxwell, Zoe Winters

Publikováno v: EBioMedicine. 83

Background: oestrogen receptor positive/ human epidermal growth factor receptor positive (ER+/HER2+) breast cancers (BCs) are less responsive to endocrine therapy than ER+/HER2- tumours. Mechanisms underpinning the differential behaviour of ER+HER2+

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f2c36f0affe9cade26299ca49ee96f2
https://pubmed.ncbi.nlm.nih.gov/35985932

United Kingdom National Health Service. Cancer Services Collaborative 'Improvement Partnership'

Autor: Clive Griffith, Jill Turner

Publikováno v: European Journal of Surgical Oncology (EJSO). 30:1-86

ABC Access, Booking and Choice (MA Programme) AC Association of Coloproctology BAUS British Association of Urological Surgeons (www.baus.org.uk) BASO British Association of Surgical Oncologists (www.baso.org) BE Barium Enema BGS British Society of Ga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6f5551097c89492381a79667bc6092d
https://doi.org/10.1016/j.ejso.2004.07.010

Aggressive local treatment for screen-Èdetected DCIS results in very low rates of recurrence

Autor: R.G Wilson, J Shrimankar, Clive Griffith, L McLean, V.S Avlonitis, M.K Jha, P.D Dawes, Thomas W. J. Lennard

Publikováno v: European Journal of Surgical Oncology (EJSO). 27:454-458

Aims: To review our institution's practice of treatment of a mammographically detected population of ductal carcinoma in situ (DCIS) patients and to determine the outcome. Methods: Between April 1989 and March 1994, 304 women with median age 59 years

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e83f3ca065b972f3aae68255480f682
https://doi.org/10.1053/ejso.2001.1163

Gynaecomastia, neurofibromatosis and breast cancer

Autor: Fiona Douglas, Colin H Wilson, Josie Shrimankar, Clive Griffith

Publikováno v: The Breast. 13:77-79

Gynaecomastia commonly affects pubertal boys. We report a rare case of bilateral ductal carcinoma in situ found incidentally after breast reduction surgery in a young man with neurofibromatosis.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56afd992e48832c627a3b5c2316f8b8d
https://doi.org/10.1016/j.breast.2003.08.002

The use of a standard proforma in breast cancer reporting

Autor: Brian Angus, Fraser Charlton, Clive Griffith, J Shrimankar, David J. Scott, ME Mathers

Publikováno v: Journal of Clinical Pathology. 54:809-811

Aim—To determine whether the introduction of a standard reporting proforma has led to an improvement in the completeness of histopathology reports for breast cancer excision specimens. Methods—A standard reporting proforma was designed using the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd4963096b857e29a4a4b304e12aab42
https://doi.org/10.1136/jcp.54.10.809