Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Clive Brown-Proctor"'
Autor:
James Bailey, Pavel Bochev, Georgiy Andreev, Doug Ferguson, Vibhudutta Awasthi, Atilio Anzellotti, Aaron McFARLAND, Clive Brown-Proctor
Publikováno v:
Journal of Radioanalytical and Nuclear Chemistry. 305:387-401
The simplification and automation of clinical PET radiotracer production, from isotope production to quality control, can streamline the current manufacturing workflow and, at the same time minimize the investment needed. In this article we present p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2d36953d24fc1c2ec057d3c99f978f2
https://doi.org/10.1007/s10967-015-4045-1
https://doi.org/10.1007/s10967-015-4045-1
Autor:
Mark A. Green, Kieren J. Mather, Clive Brown-Proctor, Steven P. Moberly, Yen Ng, Gary D. Hutchins
Publikováno v:
Nuclear Medicine and Biology. 40:361-365
Sampling of arterial blood for metabolite correction is often required to define a true radiotracer input function in quantitative modeling of PET data. However, arterial puncture for blood sampling is often undesirable. To establish whether venous b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975d59b407bdb3758983c770e8acdfcc
https://doi.org/10.1016/j.nucmedbio.2012.11.011
https://doi.org/10.1016/j.nucmedbio.2012.11.011
Autor:
Merrill J. Egorin, Clive Brown-Proctor, Paul E. Kinahan, Chester A. Mathis, Jerry M. Collins, Deborah R. Hamburger, Julie L. Eiseman, Erin Joseph, Raymond W. Klecker, Lawrence W. Anderson, Su-Shu Pan
Publikováno v:
Clinical Cancer Research. 10:6669-6676
Purpose: In colorectal, breast, and head and neck cancers, response to 5-fluorouracil is associated with low expression of thymidylate synthase. In contrast, tumors with high expression of thymidylate synthase may be more sensitive to prodrugs such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf03e2f44fc0a39ba607450c0904f2f4
https://doi.org/10.1158/1078-0432.ccr-03-0686
https://doi.org/10.1158/1078-0432.ccr-03-0686
Publikováno v:
Nuclear Medicine and Biology. 27:415-418
(E)- N -[ 11 C]Methyl-4-(3-pyridinyl)-3-butene-1-amine ([ 11 C]metanicotine), a high affinity (K i = 16 nM) CNS-selective nicotinic agonist, was prepared by the [ 11 C]alkylation of the desmethyl precursor with [ 11 C]methyl trifluoromethanesulfonate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d44f2f7cd799473a9fe4b63b36c828
https://doi.org/10.1016/s0969-8051(00)00091-3
https://doi.org/10.1016/s0969-8051(00)00091-3
Autor:
Barbara E. Glick-Wilson, Min Wang, Gary D. Hutchins, Anantha Shekhar, Qi Huang Zheng, Clive Brown-Proctor, Mingzhang Gao, Brandon L. Steele
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(14)
GSK189254 and its corresponding precursor GSK185071B were synthesized from 3-methoxyphenylacetic acid with 6-chloropyridine-3-carbolic acid or 6-chloronicotinamide in 8 and 7 steps with either 6% or 7% and either 14% or 16% yield, respectively. [ 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a851af5eb2877fe20881710f2500e5
https://pubmed.ncbi.nlm.nih.gov/22687746
https://pubmed.ncbi.nlm.nih.gov/22687746
Autor:
Barbara E. Glick-Wilson, Bruce H. Mock, Clive Brown-Proctor, Brandon L. Steele, Qi Huang Zheng, Mark A. Green
Publikováno v:
Nuclear medicine and biology. 38(8)
Introduction An automated method is described for the rapid and high-yield synthesis of two of the most commonly used radioactive fatty acids: [ 11 C]acetate and [ 11 C]palmitate. Methods Reaction of [ 11 C]CO 2 with the respective Grignard reagents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14ac55b9ba2b0664eb5973bca151f5c7
https://pubmed.ncbi.nlm.nih.gov/21831651
https://pubmed.ncbi.nlm.nih.gov/21831651
Autor:
H. Donald Gage, Michael C. Bounds, David Friedman, Michael A. Smith, Nancy Buchheimer, Joseph B. Blair, Clive Brown-Proctor, Jessica A. Henderson, Carol A. Shively
Publikováno v:
Archives of general psychiatry. 63(4)
Context Current animal models of depression are inadequate to further our understanding of depression. New models that allow for analysis of cognitive function and sex differences are needed. Objective To characterize serotonin 1A (5-HT 1A ) receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fbec1b1362e4d2b1daa827d770db943
https://pubmed.ncbi.nlm.nih.gov/16585468
https://pubmed.ncbi.nlm.nih.gov/16585468
Autor:
Julie L, Eiseman, Clive, Brown-Proctor, Paul E, Kinahan, Jerry M, Collins, Lawrence W, Anderson, Erin, Joseph, Deborah R, Hamburger, Su-Shu, Pan, Chester A, Mathis, Merrill J, Egorin, Raymond W, Klecker
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 10(19)
In colorectal, breast, and head and neck cancers, response to 5-fluorouracil is associated with low expression of thymidylate synthase. In contrast, tumors with high expression of thymidylate synthase may be more sensitive to prodrugs such as 1-(2-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b126bcd8de5968c98fef54f0972baccf
https://pubmed.ncbi.nlm.nih.gov/15475457
https://pubmed.ncbi.nlm.nih.gov/15475457
Publikováno v:
Nuclear medicine and biology. 26(1)
ABSTRACT. 6-Methoxy-3-[2-[1-(phenylmethyl)-4-piperidinyl]ethyl]-1,2-benzisoxazole is a high affinity (Ki = 8.2 nM) reversible inhibitor of acetylcholinesterase (AChE). The carbon-11 labeled form was prepared in high (>97%) radiochemical purity and wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::968451ae03d1752b60b4f9e2a867e8a5
https://pubmed.ncbi.nlm.nih.gov/10096508
https://pubmed.ncbi.nlm.nih.gov/10096508