Association of pre-existing cardiovascular disease with administration of fluoropyrimidine chemotherapy in patients with gastrointestinal malignancies

Autor: Chris Gale, Li Wei, Adam Timmis, Michael D Peake, Lucy Elliss-Brookes, Peter Ludman, Alison Fielding, David Adlam, Francis Murgatroyd, Clive Weston, Theresa McDonagh, Lizz Paley, Alistair Ring, Charlotte Manisty, Mike Hawkins, Raoul Reulen, Abbas Khushnood, Sally Vernon, John Deanfield, Nadeem Fazal, Jem Rashbass, Andrew Goodwin, Chengsheng Ju, Sarah Slater, Brian Shand, Mark De Belder, Paul Lambert, Catherine A Welch, Andrew Harrison, Michael Sweeting, Jennifer Lai, Mick Peake, Paul C Lambert, Mark de Belder, Paul Charlton, Alexander Lyon, Sarah Darby, Freya Tyrer, Mark Rutherford, Aderonke Temilade Abiodun, Pinkie Chambers, Kai Keen Shiu, Sally Jeans, Andy Deutsch, James Chal, Akosua Donkor, Anil Gunesh

Publikováno v: BMJ Oncology, Vol 3, Iss 1 (2024)

Objective Fluoropyrimidine chemotherapy is a first-line treatment for many gastrointestinal (GI) cancers, however, cardiotoxicity concerns may limit administration in patients with pre-existing cardiovascular disease (CVD). This study investigated th

Externí odkaz: https://doaj.org/article/657e4062dae14dc1813041064ef13e88

Impact of chronic kidney disease on case ascertainment for hospitalised acute myocardial infarction: an English cohort study

Autor: Jemima Scott, Fergus Caskey, Dorothea Nitsch, David Adlam, Clive Weston, Spiros Denaxas, John Deanfield, Mark De Belder, Michael Sweeting, Lucy Teece, Patrick Bidulka, Udaya Udayaraj

Publikováno v: BMJ Open, Vol 12, Iss 3 (2022)

Objectives Acute myocardial infarction (AMI) case ascertainment improves for the UK general population using linked health data sets. Because care pathways for people with chronic kidney disease (CKD) change based on disease severity, AMI case ascert

Externí odkaz: https://doaj.org/article/a38336473fbb4fa0a7bf5a2b5cd42a83

Effect of Location on Treatment and Outcomes of Cardiac Arrest Complicating Acute Myocardial Infarction in England & Wales

Autor: Muhammad Rashid, Ahmad Shoaib, Tim Kinnaird, Nick Curzen, Mohamed Dafaalla, Mamas A. Mamas, Clive Weston, Chris Stevens, Clare Appleby, Chadi Alraies, Hitinder S. Gurm

Publikováno v: The American Journal of Cardiology. 152:1-10

We investigated the incidence, management, and outcomes of acute myocardial infarction (AMI) patients according to cardiac arrest location. Patients admitted with a diagnosis of AMI between January 1, 2010 to March 31, 2017 from the Myocardial Ischae

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2606b4c3b96a211c0c154b0b3ea4d480
https://doi.org/10.1016/j.amjcard.2021.04.032

Ethnic disparities in care and outcomes of non-ST-segment elevation myocardial infarction: a nationwide cohort study

Autor: Muhammad Rashid, Clive Weston, Harriette G.C. Van Spall, Mamas A. Mamas, Saadiq M Moledina, Ahmad Shoaib, Evangelos Kontopantelis, Shrilla Banerjee, Chris P Gale, Suleman Aktaa, Aliya Kassam

Publikováno v: Moledina, S M, Shoaib, A, Weston, C, Aktaa, S, Gc Van Spall, H, Kassam, A, Kontopantelis, E, Banerjee, S, Rashid, M, Gale, C P & Mamas, M A 2021, ' Ethnic disparities in care and outcomes of non-ST-segment elevation myocardial infarction : a nationwide cohort study ', European heart journal. Quality of care & clinical outcomes . https://doi.org/10.1093/ehjqcco/qcab030

Aims Little is known about ethnic disparities in care and clinical outcomes of patients admitted with non-ST-segment elevation myocardial infarction (NSTEMI) in national cohorts from universal healthcare systems derived from Europe. Methods and resul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b25988d82eca888f1849a3b04590301
https://doi.org/10.1093/ehjqcco/qcab030

Ethnicity-dependent performance of the Global Registry of Acute Coronary Events risk score for prediction of non-ST-segment elevation myocardial infarction in-hospital mortality: nationwide cohort study

Autor: Saadiq M Moledina, Evangelos Kontopantelis, Harindra C Wijeysundera, Shrilla Banerjee, Harriette G C Van Spall, Chris P Gale, Benoy N Shah, Mohamed O Mohamed, Clive Weston, Ahmad Shoaib, Mamas A Mamas

Publikováno v: Moledina, S M, Kontopantelis, E, Wijeysundera, H C, Banerjee, S, Spall, H G C V, Gale, C P, Shah, B N, Mohamed, M O, Weston, C, Shoaib, A & Mamas, M A 2022, ' Ethnicity-dependent performance of the Global Registry of Acute Coronary Events risk score for prediction of non-ST-segment elevation myocardial infarction in-hospital mortality: nationwide cohort study ', European Heart Journal . https://doi.org/10.1093/eurheartj/ehac052

Aims The Global Registry of Acute Coronary Events (GRACE) score was developed to evaluate risk in patients with the acute coronary syndrome with or without ST-segment elevation. Little is known about its performance at predicting in-hospital mortalit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88e071a6f58cdee2c45cc81eb9773026
https://www.research.manchester.ac.uk/portal/en/publications/ethnicitydependent-performance-of-the-global-registry-of-acute-coronary-events-risk-score-for-prediction-of-nonstsegment-elevation-myocardial-infarction-inhospital-mortality-nationwide-cohort-study(aec1bc55-60a1-4308-89c9-a9999a58144a).html