Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Clive, Morris"'
Autor:
Diane J. Stevenson, Anthony J. Avery, Carol Coupland, F. D. Richard Hobbs, Denise Kendrick, Michael V. Moore, Clive Morris, Greg P. Rubin, Murray D. Smith, Christopher J. Hawkey, Jennifer S. Dumbleton
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background The Helicobacter Eradication Aspirin Trial (HEAT) is a multicentre, double blind, randomised controlled trial investigating whether Helicobacter (H.) pylori eradication reduces hospitalisation for peptic ulcer bleeding. Recruited
Externí odkaz:
https://doaj.org/article/c7aab8168a09446a93f7fd4453faf520
Autor:
Brendan Knapp, Laura Mezquita, Siddhartha Devarakonda, Mihaela Aldea, Saiama N. Waqar, Kym Pepin, Jeffrey P. Ward, Angela Botticella, Karen Howarth, Charlene Knape, Clive Morris, Ramaswamy Govindan, Benjamin Besse, Daniel Morgensztern
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionCirculating tumor DNA (ctDNA) testing may identify patients at high risk for recurrence following chemoradiation (CRT) for locally advanced non-small cell lung cancer (LA-NSCLC). We evaluated the feasibility of ctDNA testing on a readily
Externí odkaz:
https://doaj.org/article/bdec53ddcf914269b586e80415fd720d
Autor:
Jordi Remon, Aurelie Swalduz, David Planchard, Sandra Ortiz-Cuaran, Laura Mezquita, Ludovic Lacroix, Cecile Jovelet, Etienne Rouleau, Camille Leonce, Frank De Kievit, Clive Morris, Greg Jones, Kelly Mercier, Karen Howarth, Emma Green, Maurice Pérol, Pierre Saintigny, Benjamin Besse
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234302 (2020)
Circulating tumor DNA (ctDNA)-based molecular profiling is rapidly gaining traction in clinical practice of advanced cancer patients with multi-gene next-generation sequencing (NGS) panels. However, clinical outcomes remain poorly described and deser
Externí odkaz:
https://doaj.org/article/93ae8d067940452fb391568395e4fc0e
Autor:
David Planchard, Pierre Saintigny, Jean-Yves Blay, Benjamin Besse, Maurice Perol, Jean-François Guichou, Sylvie Chabaud, Luc Friboulet, Emma Green, Clive Morris, Karen Howarth, Frank de Kievit, Natalie Hoog-Labouret, Celine Mahier-Aït Oukhatar, Caroline Caramella, Etienne Giroux Leprieur, Isabelle Monnet, Etienne Brain, Radj Gervais, Christine Raynaud, Claire Tissot, Maud Ngo-Camus, Virginie Westeel, Yohann Loriot, Ludovic Lacroix, Washington R. Chumbi Flores, Virginie Avrillon, Anne Pradines, Cecile Jovelet, Camille Leonce, Julien Mazieres, Mihalea Aldea, Aurélie Swalduz, Laura Mezquita, Sandra Ortiz-Cuaran
Purpose:The limited knowledge on the molecular profile of patients with BRAF-mutant non–small cell lung cancer (NSCLC) who progress under BRAF-targeted therapies (BRAF-TT) has hampered the development of subsequent therapeutic strategies for these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36ac9163cfbba9d2de50090974b699f2
https://doi.org/10.1158/1078-0432.c.6530096
https://doi.org/10.1158/1078-0432.c.6530096
Autor:
Carla M.L. van Herpen, Paul D. Smith, Sarah M.A. George, Clive Morris, Mireille V. Cantarini, Kathryn H. Brown, Karl D. Lewis, S. Gail Eckhardt, Johanna N.H. Timmer-Bonte, Ingrid M.E. Desar, Stan B. Kaye, Debashis Sarker, Roshan Agarwal, Henk M.W. Verheul, D. Ross Camidge, Udai Banerji
Purpose: In part A, the aim was to define the maximum tolerated dose (MTD) of the hydrogen sulfate (Hyd-Sulfate) oral capsule formulation of the mitogen-activated protein kinase kinase inhibitor AZD6244 (ARRY-142886). In part B, the aim was to compar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208177023d9f47dfc08332fb4ee6f5bd
https://doi.org/10.1158/1078-0432.c.6518778
https://doi.org/10.1158/1078-0432.c.6518778
Autor:
Carla M.L. van Herpen, Paul D. Smith, Sarah M.A. George, Clive Morris, Mireille V. Cantarini, Kathryn H. Brown, Karl D. Lewis, S. Gail Eckhardt, Johanna N.H. Timmer-Bonte, Ingrid M.E. Desar, Stan B. Kaye, Debashis Sarker, Roshan Agarwal, Henk M.W. Verheul, D. Ross Camidge, Udai Banerji
Supplementary Data from The First-in-Human Study of the Hydrogen Sulfate (Hyd-Sulfate) Capsule of the MEK1/2 Inhibitor AZD6244 (ARRY-142886): A Phase I Open-Label Multicenter Trial in Patients with Advanced Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ba00bb25181e63843a9e6fcdc6379c4
https://doi.org/10.1158/1078-0432.22441902.v1
https://doi.org/10.1158/1078-0432.22441902.v1
Publikováno v:
Circular Economy and Sustainability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4182b406adc7afcfcd3e4e5988d2baa9
https://doi.org/10.1007/s43615-023-00259-0
https://doi.org/10.1007/s43615-023-00259-0
Publikováno v:
Circular Economy and Sustainability. 3:199-220
Around 20% of the global water abstractions are originated by the industrial sector, while water demand overall will increase by 20–33% by 2050. Wastewater could provide an alternative source of water for industrial activities. There are not many s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab66fc7590878d6fec49909ad7fe4a44
https://doi.org/10.1007/s43615-022-00166-w
https://doi.org/10.1007/s43615-022-00166-w
Autor:
Daniel A, Breadner, Mark D, Vincent, Rohann, Correa, Morgan, Black, Andrew, Warner, Michael, Sanatani, Vasudeva, Bhat, Clive, Morris, Greg, Jones, Alison, Allan, David A, Palma, Jacques, Raphael
Publikováno v:
Lung Cancer. 165:145-151
Blood-based liquid biopsies examining circulating tumour DNA (ctDNA) have increasing applications in non-small cell lung cancer (NSCLC). Limitations in sensitivity remain a barrier to ctDNA replacing tissue-based testing. We hypothesized that testing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1786d6a5b6f2a3c30a4116cd5d150a59
https://doi.org/10.1016/j.lungcan.2022.01.013
https://doi.org/10.1016/j.lungcan.2022.01.013
Autor:
Vincent Plagnol, Samuel Woodhouse, Karen Howarth, Stefanie Lensing, Matt Smith, Michael Epstein, Mikidache Madi, Sarah Smalley, Catherine Leroy, Jonathan Hinton, Frank de Kievit, Esther Musgrave-Brown, Colin Herd, Katherine Baker-Neblett, Will Brennan, Peter Dimitrov, Nathan Campbell, Clive Morris, Nitzan Rosenfeld, James Clark, Davina Gale, Jamie Platt, John Calaway, Greg Jones, Tim Forshew
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193802 (2018)
Circulating tumor DNA (ctDNA) analysis is being incorporated into cancer care; notably in profiling patients to guide treatment decisions. Responses to targeted therapies have been observed in patients with actionable mutations detected in plasma DNA
Externí odkaz:
https://doaj.org/article/913109ecaadf42f485c31e026d8daca3