Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Clinton Van't Land"'
Autor:
Huabo Wang, Taylor Stevens, Jie Lu, Alexander Roberts, Clinton Van't Land, Radhika Muzumdar, Zhenwei Gong, Jerry Vockley, Edward V. Prochownik
Publikováno v:
Advanced Science, Vol 11, Iss 34, Pp n/a-n/a (2024)
Abstract The “Mlx” and “Myc” transcription factor networks cross‐communicate and share many common gene targets. Myc's activity depends upon its heterodimerization with Max, whereas the Mlx Network requires that the Max‐like factor Mlx as
Externí odkaz:
https://doaj.org/article/21d46c4a8a1c4ee19059c58c19da19c0
Autor:
Stephanie M. Casillo, Taylor A. Gatesman, Akanksha Chilukuri, Srinidhi Varadharajan, Brenden J. Johnson, Daniel R. David Premkumar, Esther P. Jane, Tritan J. Plute, Robert F. Koncar, Ann-Catherine J. Stanton, Carlos A.O. Biagi-Junior, Callie S. Barber, Matthew E. Halbert, Brian J. Golbourn, Katharine Halligan, Andrea F. Cruz, Neveen M. Mansi, Allison Cheney, Steven J. Mullett, Clinton Van’t Land, Jennifer L. Perez, Max I. Myers, Nishant Agrawal, Joshua J. Michel, Yue-Fang Chang, Olena M. Vaske, Antony MichaelRaj, Frank S. Lieberman, James Felker, Sruti Shiva, Kelsey C. Bertrand, Nduka Amankulor, Costas G. Hadjipanayis, Kalil G. Abdullah, Pascal O. Zinn, Robert M. Friedlander, Taylor J. Abel, Javad Nazarian, Sriram Venneti, Mariella G. Filbin, Stacy L. Gelhaus, Stephen C. Mack, Ian F. Pollack, Sameer Agnihotri
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113557- (2024)
Summary: Metabolic reprogramming in pediatric diffuse midline glioma is driven by gene expression changes induced by the hallmark histone mutation H3K27M, which results in aberrantly permissive activation of oncogenic signaling pathways. Previous stu
Externí odkaz:
https://doaj.org/article/a1cfb726d57743518bf0449e2947643f
Autor:
Huabo Wang, Jie Lu, Taylor Stevens, Alexander Roberts, Jordan Mandel, Raghunandan Avula, Bingwei Ma, Yijen Wu, Jinglin Wang, Clinton Van’t Land, Toren Finkel, Jerry E. Vockley, Merlin Airik, Rannar Airik, Radhika Muzumdar, Zhenwei Gong, Michel S. Torbenson, Edward V. Prochownik
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112830- (2023)
Summary: MYC proto-oncogene dysregulation alters metabolism, translation, and other functions in ways that support tumor induction and maintenance. Although Myc+/− mice are healthier and longer-lived than control mice, the long-term ramifications o
Externí odkaz:
https://doaj.org/article/592f094c57b94e779a6b09c1d1c41fbf
Autor:
Olivia M. D’Annibale, Yu Leng Phua, Clinton Van’t Land, Anuradha Karunanidhi, Alejandro Dorenbaum, Al-Walid Mohsen, Jerry Vockley
Publikováno v:
Cells, Vol 11, Iss 17, p 2635 (2022)
Background: Very long-chain acyl-CoA dehydrogenase (VLCAD) deficiency is an autosomal recessive disease that prevents the body from utilizing long-chain fatty acids for energy, most needed during stress and fasting. Symptoms can appear from infancy t
Externí odkaz:
https://doaj.org/article/7cdeef019e9f44d2ab85e37c8a9049b3
Autor:
Xue-Jun Zhao, Ai-Walid Mohsen, Stephanie Mihalik, Keaton Solo, Shakuntala Basu, Ermal Aliu, Huifang Shi, Catherine Kochersberger, Anuradha Karunanidhi, Clinton Van’t Land, Kimberly A Coughlan, Summar Siddiqui, Lisa M Rice, Shawn Hillier, Eleonora Guadagnin, Christine DeAntonis, Paloma H Giangrande, Paolo G V Martini, Jerry Vockley
Publikováno v:
Human Molecular Genetics.
Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency is the most common inherited disorder of mitochondrial fatty acid β-oxidation (FAO) in humans. Patients exhibit clinical episodes often associated with fasting. Symptoms include hypoketotic hypog
Autor:
Huabo Wang, Jie Lu, Taylor Stevens, Alexander Roberts, Jordan Mandel, Raghunandan Avula, Yijen Wu, Jinglin Wang, Clinton Van’t Land, Toren Finkel, Jerry E. Vockley, Merlin Airik, Rannar Airik, Radhika Muzumdar, Zhenwei Gong, Michel S. Torbenson, Edward V. Prochownik
MYC proto-oncogene dysregulation alters metabolic, translational, cell cycle and other functions in ways that support tumor induction and maintenance. Myc+/- mice are healthier and longer-lived than control mice but the long-term ramifications of mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df06b03a5964902c51d662caebe1eeab
https://doi.org/10.1101/2023.01.30.526354
https://doi.org/10.1101/2023.01.30.526354
Autor:
Anuradha Karunanidhi, Clinton Van't Land, Dhivyaa Rajasundaram, Mateus Grings, Jerry Vockley, Al‐Walid Mohsen
Publikováno v:
J Inherit Metab Dis
Inherited errors of mitochondrial fatty acid β-oxidation (FAO) are life threatening, even with optimum care. FAO is the major source of energy for heart and is critical for skeletal muscles especially during physiologic stress. Clinical trials revea
Autor:
Xue-Jun Zhao, AI-Walid Mohsen, Stephanie Mihalik, Keaton Solo, Ermal Aliu, Huifang Shi, Shakuntala Basu, Catherine Kochersperger, Clinton Van’t Land, Anuradha Karunanidhi, Kimberly A. Coughlan, Summar Siddiqui, Lisa M. Rice, Shawn Hillier, Eleonora Guadagnin, Paloma H. Giangrande, Paolo G.V. Martini, Jerry Vockley
Publikováno v:
Molecular genetics and metabolism. 138(1)
Very long-chain acyl-CoA dehydrogenase (VLCAD) deficiency is an inborn error of long chain fatty acid β-oxidation (FAO) with limited treatment options. Patients present with heterogeneous clinical phenotypes affecting predominantly heart, liver, and
Autor:
Eduardo Vieira Neto, Meicheng Wang, Tamil Anthonymuthu, Austin Szuminsky, Clinton Van't Land, Yudong Wang, Hülya Bayır, Jerry Vockley
Publikováno v:
Genetics in Medicine. 24:S337-S339
Autor:
Anuradha Karunanidhi, Shakuntala Basu, Xuejun Zhao, Clinton Van't land, Jerry Vockley, Al-Walid Mohsen
Publikováno v:
Molecular Genetics and Metabolism. 138:107436