Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Clinton T. Elfers"'
Autor:
James E. Blevins, Mackenzie K. Honeycutt, Jared D. Slattery, Matvey Goldberg, June R. Rambousek, Edison Tsui, Andrew D. Dodson, Kyra A. Shelton, Therese S. Salemeh, Clinton T. Elfers, Kylie S. Chichura, Emily F. Ashlaw, Sakeneh Zraika, Robert P. Doyle, Christian L. Roth
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
We recently reported that a novel chimeric peptide (GEP44) targeting both the glucagon-like peptide-1 receptor (GLP-1R) and neuropeptide Y1- and Y2 receptor (Y1R and Y2R) reduced energy intake and body weight (BW) in diet-induced obese (DIO) rats. We
Externí odkaz:
https://doaj.org/article/529ad7d0cfa24b59b26ce81122b9ef1b
Autor:
Kylie S. Chichura, Clinton T. Elfers, Therese S. Salameh, Varun Kamat, Oleg G. Chepurny, Aelish McGivney, Brandon T. Milliken, George G. Holz, Sarah V. Applebey, Matthew R. Hayes, Ian R. Sweet, Christian L. Roth, Robert P. Doyle
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Mechanisms underlying long-term sustained weight loss and glycemic normalization after obesity surgery include changes in gut hormone levels, including glucagon-like peptide 1 (GLP-1) and peptide YY (PYY). We demonstrate that two peptide bia
Externí odkaz:
https://doaj.org/article/dc106d853e6f471fa38cee689f96ea30
Autor:
Clinton T. Elfers, James E. Blevins, Elizabeth A. Lawson, Richard Pittner, David Silva, Alex Kiselyov, Christian L. Roth
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Background: Oxytocin is a hypothalamic neuropeptide that participates in the network of appetite regulation. Recently the oxytocin signaling pathway has emerged as an attractive target for treating obesity. However, the short half-life limits its dev
Externí odkaz:
https://doaj.org/article/29db56b194924c0caf182c7f65e2ac73
Autor:
Christian L Roth, Susan J Melhorn, Mary Rosalynn B De Leon, Maya G Rowland, Clinton T Elfers, Alyssa Huang, Brian E Saelens, Ellen A Schur
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 107:2254-2266
Context Obesity interventions often result in increased motivation to eat. Objective We investigated relationships between obesity outcomes and changes in brain activation by visual food cues and hormone levels in response to obesity intervention by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c63b2124eb031b4cca719f46c2e1cfdb
https://doi.org/10.1210/clinem/dgac299
https://doi.org/10.1210/clinem/dgac299
Autor:
Kylie S. Chichura, Clinton T. Elfers, Therese Salameh, Varun Kamat, Oleg G. Chepurny, Aelish McGivney, Brandon T. Milliken, George G. Holz, Sarah V. Applebey, Matthew R. Hayes, Ian R. Sweet, Christian L. Roth, Robert P. Doyle
SUMMARYMechanisms underlying long-term sustained weight loss and glycemic normalization after obesity surgery include changes in gut hormone levels, including glucagon-like peptide 1 (GLP-1) and peptide YY (PYY). We demonstrate that two peptide biase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4a1edc9bb65350578efbaeb4a774647
https://doi.org/10.1101/2022.11.07.515458
https://doi.org/10.1101/2022.11.07.515458
Autor:
Clinton T, Elfers, James E, Blevins, Therese S, Salameh, Elizabeth A, Lawson, David, Silva, Alex, Kiselyov, Christian L, Roth
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11249
Oxytocin (OXT) analogues have been designed to overcome the limitation of the short half-life of the native OXT peptide. Here, we tested ASK2131 on obesity related outcomes in diet-induced obese (DIO) Sprague Dawley rats. In vitro function assays wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898cfb2e7fea5c579ba1141798dd836b
https://doi.org/10.3390/ijms231911249
https://doi.org/10.3390/ijms231911249