Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Clinton S. George"'
Autor:
Tracy E. Strecker, Chen-Ming Lin, Clinton S. George, Ernest Hamel, Christine A. Herdman, Mary Lynn Trawick, Kevin G. Pinney, Ralph P. Mason, Laxman Devkota, David J. Chaplin, Li Liu, Haichan Niu, Ramona Lopez, Rajendra P. Tanpure
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:7497-7520
The discovery of 3-methoxy-9-(3′,4′,5′-trimethoxyphenyl)-6,7-dihydro-5H-benzo[7]annulen-4-ol (a benzosuberene-based analogue referred to as KGP18) was originally inspired by the natural products colchicine and combretastatin A-4 (CA4). The rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365d53f29a62ebcd3ca40c733d373ca0
https://doi.org/10.1016/j.bmc.2015.10.012
https://doi.org/10.1016/j.bmc.2015.10.012
Autor:
Kevin G. Pinney, Rajendra P. Tanpure, Christine A. Herdman, Chen-Ming Lin, David J. Chaplin, Matthew T. MacDonough, Laxman Devkota, Mary Lynn Trawick, Justin K. Tidmore, Tracy E. Strecker, Clinton S. George, Madhavi Sriram
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:8019-8032
Diversely functionalized, fused aryl-alkyl ring systems hold a prominent position as well-established molecular frameworks for a variety of anti-cancer agents. The benzosuberene (6,7 fused, also referred to as dihydro-5H-benzo[7]annulene and benzocyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b2ffe22c532e72ae6d7ebeb9c2156ab
https://doi.org/10.1016/j.bmc.2013.08.035
https://doi.org/10.1016/j.bmc.2013.08.035
Autor:
Kevin G. Pinney, Clinton S. George, Madhavi Sriram, David J. Chaplin, Rajendra P. Tanpure, Samuel O. Odutola, Amanda K. Charlton-Sevcik, Mary Lynn Trawick, Tracy E. Strecker, Justin K. Tidmore
Publikováno v:
The FASEB Journal. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d45b2d4e155c2165d45430db856f369
https://doi.org/10.1096/fasebj.26.1_supplement.613.5
https://doi.org/10.1096/fasebj.26.1_supplement.613.5
Autor:
Samuel O. Odutola, Rajendra P. Tanpure, Kevin G. Pinney, Clinton S. George, Tracy E. Strecker, David J. Chaplin, Madhavi Sriram, Justin K. Tidmore, Mary Lynn Trawick, Amanda K. Charlton-Sevcik
Publikováno v:
The FASEB Journal. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ae11ed407f832af8c785a50e57148b4
https://doi.org/10.1096/fasebj.26.1_supplement.999.8
https://doi.org/10.1096/fasebj.26.1_supplement.999.8
Autor:
Kevin G. Pinney, Mary Lynn Trawick, David J. Chaplin, Tracy E. Strecker, Rajendra P. Tanpure, Amanda K. Charlton-Sevcik, Justin K. Tidmore, Ernest Hamel, Clinton S. George, Madhavi Sriram
Publikováno v:
MedChemComm. 3:720
The recent discovery of a small-molecule benzosuberene-based phenol that demonstrates remarkable picomolar cytotoxicity against selected human cancer cell lines and strongly inhibits tubulin polymerization (1–2 µM) inspired the design and synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db641b90b7e84d4f63ba2370ec18c815
https://doi.org/10.1039/c2md00318j
https://doi.org/10.1039/c2md00318j