Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Clinton M, Heinze"'
1
Akademický článek
In situ vaccination at a peripheral tumor site augments response against melanoma brain metastases
Autor: Raghava N Sriramaneni, Justin C Jagodinsky, Abigail A Jaquish, Bryce R Anderson, Trang Le, Jonathan A Lubin, Ishan Chakravarty, Ian S Arthur, Clinton M Heinze, Kelsey A Klar, John S Kuo
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Immune checkpoint inhibition (ICI) alone is not efficacious for a large number of patients with melanoma brain metastases. We previously established an in situ vaccination (ISV) regimen combining radiation and immunocytokine to enhance res
Externí odkaz: https://doaj.org/article/5403053984ba479cad7610cc87ac2b46
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2
Akademický článek
In situ Vaccine Plus Checkpoint Blockade Induces Memory Humoral Response
Autor: Claire C. Baniel, Clinton M. Heinze, Anna Hoefges, Elizabeth G. Sumiec, Jaquelyn A. Hank, Peter M. Carlson, Won Jong Jin, Ravi B. Patel, Raghava N. Sriramaneni, Stephen D. Gillies, Amy K. Erbe, Ciara N. Schwarz, Alexander A. Pieper, Alexander L. Rakhmilevich, Paul M. Sondel, Zachary S. Morris
Publikováno v: Frontiers in Immunology, Vol 11 (2020)
In a syngeneic murine melanoma (MEL) model, we recently reported an in situ vaccination response to combined radiation (RT) and intra-tumoral (IT) injection of anti-GD2 hu14. 18-IL2 immunocytokine (IC). This combined treatment resulted in 71% complet
Externí odkaz: https://doaj.org/article/69d352c38672413f9676b26e4741f6de
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6
In situ vaccination at a peripheral tumor site augments response against melanoma brain metastases
Autor: Zachary S. Morris, Paul A. Clark, Ian S. Arthur, Won Jong Jin, Kelsey A Klar, Jonathan A. Lubin, Jasdeep S. Kler, Amber M. Bates, John S. Kuo, Ishan Chakravarty, Bryce R. Anderson, Raghava N. Sriramaneni, Emily I. Guy, Justin C. Jagodinsky, Abigail A Jaquish, Trang T. Le, Clinton M. Heinze, Peter M. Carlson, Kyung Mann Kim
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
BackgroundImmune checkpoint inhibition (ICI) alone is not efficacious for a large number of patients with melanoma brain metastases. We previously established an in situ vaccination (ISV) regimen combining radiation and immunocytokine to enhance resp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d372b4357eddd899b143a36b2b6a90
https://jitc.bmj.com/content/8/2/e000809.full
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7
Tumor-Specific Inhibition ofIn SituVaccination by Distant Untreated Tumor Sites
Autor: Alan J. Korman, Jacquelyn A. Hank, Zachary S. Morris, Stephen D. Gillies, Paul M. Harari, Hans Loibner, Sara M. Busche, Emily I. Guy, Alexander L. Rakhmilevich, Lakeesha Carmichael, Lauryn R. Werner, Paul M. Sondel, Abigail A Jaquish, Raghava N. Sriramaneni, Jasdeep S. Kler, Amy K. Erbe, Clinton M. Heinze, Peter M. Carlson
Publikováno v: Cancer Immunology Research. 6:825-834
In situ vaccination is an emerging cancer treatment strategy that uses local therapies to stimulate a systemic antitumor immune response. We previously reported an in situ vaccination effect when combining radiation (RT) with intratumor (IT) injectio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a73836d17be5e759b6a13dc3b942c007
https://doi.org/10.1158/2326-6066.cir-17-0353
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8
Transcriptional-mediated effects of radiation on the expression of immune susceptibility markers in melanoma
Autor: Ravi Patel, Zachary S. Morris, Amy K. Erbe, Maureen Riegert, Lauryn R. Werner, Clinton M. Heinze, Joseph Kern, Mahyar Abbariki, Raghava N. Sriramaneni, Lindsey K. Werner, Monica M. Gressett, Paul M. Harari, Jasdeep S. Kler
Publikováno v: Radiotherapy and Oncology. 124:418-426
Background and purpose We recently reported a time-sensitive, cooperative, anti-tumor effect elicited by radiation (RT) and intra-tumoral-immunocytokine injection in vivo . We hypothesized that RT triggers transcriptional-mediated changes in tumor ex
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8ac2800a8a808bbfea7960002c8bbc
https://doi.org/10.1016/j.radonc.2017.08.016
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9
Tumor-Specific Inhibition of
Autor: Zachary S, Morris, Emily I, Guy, Lauryn R, Werner, Peter M, Carlson, Clinton M, Heinze, Jasdeep S, Kler, Sara M, Busche, Abigail A, Jaquish, Raghava N, Sriramaneni, Lakeesha L, Carmichael, Hans, Loibner, Stephen D, Gillies, Alan J, Korman, Amy K, Erbe, Jacquelyn A, Hank, Alexander L, Rakhmilevich, Paul M, Harari, Paul M, Sondel
Publikováno v: Cancer immunology research. 6(7)
In situ vaccination is an emerging cancer treatment strategy that uses local therapies to stimulate a systemic antitumor immune response. We previously reported an in situ vaccination effect when combining radiation (RT) with intra-tumor (IT) injecti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::523b2b3e6309de6bb6fc68948e39ec70
https://pubmed.ncbi.nlm.nih.gov/29748391
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