Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Clinton L Cario"'
Autor:
Clinton L Cario, John S Witte
Publikováno v:
BioTechniques, Vol 65, Iss 6, Pp 357-360 (2018)
Sample automation and management is increasingly important as the number and size of population-scale and high-throughput projects grow. This is particularly the case in large-scale population studies where sample size is far outpacing the commonly u
Externí odkaz:
https://doaj.org/article/f28e0b121005411098a2916b978ad5f0
Autor:
David Mavor, Kyle Barlow, Samuel Thompson, Benjamin A Barad, Alain R Bonny, Clinton L Cario, Garrett Gaskins, Zairan Liu, Laura Deming, Seth D Axen, Elena Caceres, Weilin Chen, Adolfo Cuesta, Rachel E Gate, Evan M Green, Kaitlin R Hulce, Weiyue Ji, Lillian R Kenner, Bruk Mensa, Leanna S Morinishi, Steven M Moss, Marco Mravic, Ryan K Muir, Stefan Niekamp, Chimno I Nnadi, Eugene Palovcak, Erin M Poss, Tyler D Ross, Eugenia C Salcedo, Stephanie K See, Meena Subramaniam, Allison W Wong, Jennifer Li, Kurt S Thorn, Shane Ó Conchúir, Benjamin P Roscoe, Eric D Chow, Joseph L DeRisi, Tanja Kortemme, Daniel N Bolon, James S Fraser
Publikováno v:
eLife, Vol 5 (2016)
Ubiquitin is essential for eukaryotic life and varies in only 3 amino acid positions between yeast and humans. However, recent deep sequencing studies indicate that ubiquitin is highly tolerant to single mutations. We hypothesized that this tolerance
Externí odkaz:
https://doaj.org/article/f3e8373dbc7b4012a1c82425c9fb49fb
Autor:
Clinton L. Cario, Emmalyn Chen, Lancelote Leong, Nima C. Emami, Karen Lopez, Imelda Tenggara, Jeffry P. Simko, Terence W. Friedlander, Patricia S. Li, Pamela L. Paris, Peter R. Carroll, John S. Witte
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Cell-free DNA’s (cfDNA) use as a biomarker in cancer is challenging due to genetic heterogeneity of malignancies and rarity of tumor-derived molecules. Here we describe and demonstrate a novel machine-learning guided panel desig
Externí odkaz:
https://doaj.org/article/4b8f1ffaa66a497293d31c9ad249bfe8
Autor:
John S. Witte, Neil Risch, Catherine Schaefer, Pui-Yan Kwok, Mark N. Kvale, Daniela Seminara, Brian E. Henderson, Christopher A. Haiman, Lorelei A. Mucci, Kathryn L. Penney, Matthew L. Freedman, Qiyuan Li, Stephen N. Thibodeau, Daniel J. Schaid, Amy J. French, Shannon K. McDonnell, Stephen J. Chanock, Sonja I. Berndt, Zhaoming Wang, Joseph Presti, David Aaronson, Charles P. Quesenberry, Dilrini K. Ranatunga, Jun Shan, Nirupa R. Ghai, Chun R. Chao, Nima C. Emami, Clinton L. Cario, Michael N. Passarelli, Rebecca E. Graff, Laurel A. Habel, Eric Jorgenson, Lori C. Sakoda, Stephen K. Van Den Eeden, Thomas J. Hoffmann
Supplementary Table S1. Descriptive factors for KP study population, broken down by study. Supplementary Table S2. Genome-wide significant SNPs found in our cohort. Supplementary Table S3. Cis-eQTL expression of rs4646284. Supplementary Table S4. Res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b2bff2d8c86df2754f6553c7b45ff9
https://doi.org/10.1158/2159-8290.22531545
https://doi.org/10.1158/2159-8290.22531545
Autor:
John S. Witte, Stephen K. Van Den Eeden, Thomas J. Hoffmann, Neil Risch, Catherine Schaefer, Pui-Yan Kwok, Mark N. Kvale, Lori C. Sakoda, Eric Jorgenson, Nirupa R. Ghai, Chun R. Chao, Dilrini K. Ranatunga, Jun Shan, Laurel A. Habel, Joseph Presti, David Aaronson, Simon Wong, Eunice Wan, Linda Kachuri, Joel A. Mefford, Caroline G. Tai, Rebecca E. Graff, Clinton L. Cario, Sara R. Rashkin, Taylor B. Cavazos, Nima C. Emami
Figure S1-S6, Table S1-S10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3832c1cc5a2ef438ce0e17b1f933c0
https://doi.org/10.1158/0008-5472.22428541.v1
https://doi.org/10.1158/0008-5472.22428541.v1
Autor:
Terence W. Friedlander, Pamela L. Paris, Patricia Li, Karen Lopez, Rahul Aggarwal, Clinton L. Cario, Alexander W. Wyatt, Imelda Tenggara, Felix Y. Feng, Emmalyn Chen, Cesar P Marquez, Erica Oropeza, Jeffry P. Simko, Lancelote Leong, Carissa Chu, June M. Chan, Peter R. Carroll, John S. Witte, Janet E. Cowan
Publikováno v:
Scientific Reports
Scientific reports, vol 11, iss 1
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific reports, vol 11, iss 1
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Prostate cancer is the most commonly diagnosed neoplasm in American men. Although existing biomarkers may detect localized prostate cancer, additional strategies are necessary for improving detection and identifying aggressive disease that may requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb20a350b569827eda837c42b48a7a8c
http://europepmc.org/articles/PMC7930042
http://europepmc.org/articles/PMC7930042
Autor:
Felix Y. Feng, Peter R. Carroll, John S. Witte, Lancelote Leong, Terence W. Friedlander, Imelda Tenggara, Jeffry P. Simko, Daniel K. Wells, Erica Oropeza, Rahul Aggarwal, Emmalyn Chen, June M. Chan, Clinton L. Cario, Robin Kageyama, Janet E. Cowan, Cesar P Marquez, Karen Lopez, Pamela L. Paris, Patricia Li
Publikováno v:
JCO precision oncology, vol 5, iss 5
JCO Precis Oncol
JCO Precis Oncol
PURPOSE Cell-free DNA (cfDNA) may allow for minimally invasive identification of biologically relevant genomic alterations and genetically distinct tumor subclones. Although existing biomarkers may detect localized prostate cancer, additional strateg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920052ef65ba87427dfe5fc855a3e8d5
https://escholarship.org/uc/item/07m4h3sd
https://escholarship.org/uc/item/07m4h3sd
Autor:
Karen Lopez, Terence W. Friedlander, Pamela L. Paris, Lancelote Leong, Patricia Li, Imelda Tenggara, John S. Witte, Nima C. Emami, Emmalyn Chen, Clinton L. Cario, Jeffry P. Simko, Peter R. Carroll
Publikováno v:
BMC cancer, vol 20, iss 1
BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)
BMC Cancer
BackgroundCell-free DNA’s (cfDNA) use as a biomarker in cancer is challenging due to genetic heterogeneity of malignancies and rarity of tumor-derived molecules. Here we describe and demonstrate a novel machine-learning guided panel design strategy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc638658527357621eacec5ed9be69a
https://escholarship.org/uc/item/7pr3j4sj
https://escholarship.org/uc/item/7pr3j4sj
Cell-free DNA as a biomarker for prostate cancer: elevated concentration and decreased fragment size
Autor:
June M. L. Chan, John S. Witte, Pamela L. Paris, Patricia Li, Cesar P Marquez, Lancelote Leong, Terence W. Friedlander, Peter R. Carroll, Janet E. Cowan, Rahul Aggarwal, Carissa Chu, Erica Oropeza, Imelda Tenggara, Karen Lopez, Clinton L. Cario, Alexander W. Wyatt, Emmalyn Chen, Felix Feng, Jeffry P. Simko
PurposeProstate cancer is the most commonly diagnosed neoplasm in American men. Although existing biomarkers may detect localized prostate cancer, additional strategies are necessary for improving detection and identifying aggressive disease that may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edae3ca5bafa2cfe5c61022a507380c6
https://doi.org/10.1101/2020.07.26.215020
https://doi.org/10.1101/2020.07.26.215020
Autor:
Rebecca E. Graff, Caroline G. Tai, Pui-Yan Kwok, Chun Chao, Clinton L. Cario, Jun Shan, Thomas J. Hoffmann, John S. Witte, Lori C. Sakoda, Stephen K. Van Den Eeden, Taylor B. Cavazos, David S. Aaronson, Nirupa R. Ghai, Joel Mefford, Neil Risch, Laurel A. Habel, Linda Kachuri, Eunice Wan, Nima C. Emami, Simon Wong, Sara R. Rashkin, Dilrini K. Ranatunga, Mark N. Kvale, Joseph C. Presti, Catherine Schaefer, Eric Jorgenson
The potential association between rare germline genetic variants and prostate cancer (PrCa) susceptibility has been understudied due to challenges with assessing rare variation. Furthermore, although common risk variants for PrCa have shown limited i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1906ded25035f4ad932d624a09e262cb
https://doi.org/10.1101/2020.02.12.929463
https://doi.org/10.1101/2020.02.12.929463