Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Clinton G. L. Veale"'
Autor:
Ayanda I. Zulu, Ogunyemi O. Oderinlo, Cuan Kruger, Michelle Isaacs, Heinrich C. Hoppe, Vincent J. Smith, Clinton G. L. Veale, Setshaba D. Khanye
Publikováno v:
Molecules, Vol 25, Iss 7, p 1668 (2020)
With an intention of identifying chalcone derivatives exhibiting anti-protozoal activity, a cohort of relatively unexplored arylpyrrole-based chalcone derivatives were synthesized in moderate to good yields. The resultant compounds were evaluated in
Externí odkaz:
https://doaj.org/article/5632225a6c31411b952e7c68a3807e43
Publikováno v:
Marine Drugs, Vol 13, Iss 10, Pp 6366-6383 (2015)
Recent developments in marine drug discovery from three South African marine invertebrates, the tube worm Cephalodiscus gilchristi, the ascidian Lissoclinum sp. and the sponge Topsentia pachastrelloides, are presented. Recent reports of the bioactivi
Externí odkaz:
https://doaj.org/article/3d6561bba390461bb68aee5944321a1a
Autor:
K. P. Nandhini, Mahama Alhassan, Clinton G. L. Veale, Fernando Albericio, Beatriz G. de la Torre
Publikováno v:
ACS Omega. 8:15631-15637
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4365ebaa08997cb51a3425c42835fee5
https://doi.org/10.1021/acsomega.3c01058
https://doi.org/10.1021/acsomega.3c01058
Publikováno v:
Synlett. 33:1907-1912
Controlled sulfonyl migration is considered an important transformation for total synthesis and scaffold elaboration. Accordingly, efforts to understand the underlying properties of these often serendipitously identified reactions have important impl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dae813f7f67279d221ec2c04242af57
https://doi.org/10.1055/a-1893-7550
https://doi.org/10.1055/a-1893-7550
Publikováno v:
ChemBioChem. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff09b4811322dd47e98d46a4999af150
https://doi.org/10.1002/cbic.202300060
https://doi.org/10.1002/cbic.202300060
Publikováno v:
ACS Chemical Biology. 17:728-743
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ceb8cb20322f5f2379e5b8af9cc2f35
https://doi.org/10.1021/acschembio.2c00209
https://doi.org/10.1021/acschembio.2c00209
Autor:
Clinton G. L. Veale
Publikováno v:
Journal of Chemical Education. 99:1497-1502
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ae97c21ea1afa2933ac000369e42ac0
https://doi.org/10.1021/acs.jchemed.1c01075
https://doi.org/10.1021/acs.jchemed.1c01075
Autor:
Michaelone C. Vaaltyn, Maria Mateos‐Jimenez, Ronel Müller, C. Logan Mackay, Adrienne L. Edkins, David J. Clarke, Clinton G. L. Veale
Publikováno v:
Vaaltyn, M C, Mateos-Jimenez, M, Müller, R, Mackay, C L, Edkins, A L, Clarke, D J & Veale, C G L 2022, ' Native Mass Spectrometry-Guided Screening Identifies Hit Fragments for HOP-HSP90 PPI Inhibition ', ChemBioChem, vol. 23, no. 21, e202200322 . https://doi.org/10.1002/cbic.202200322
Contemporary medicinal chemistry considers fragment-based drug discovery (FBDD) and inhibition of protein-protein interactions (PPI) as important means of expanding the volume of druggable chemical space. However, the ability to robustly identify val
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a05b80818b6cfa4dc4aed3b4709b2a
https://pubmed.ncbi.nlm.nih.gov/36017658
https://pubmed.ncbi.nlm.nih.gov/36017658
Autor:
Weiyang Chen, Sushil K Chaudhary, Clinton G. L. Veale, Sandy van Vuuren, Sandra Combrinck, Khotso Serabele, Sidonie Tankeu, Alvaro M. Viljoen
Publikováno v:
South African Journal of Botany. 137:117-132
Helichrysum petiolare and Helichrysum odoratissimum, collectively known as ‘Imphepho’, are popular medicinal herbs that are indigenous to South Africa. The species are used interchangeably to relieve gastrointestinal and respiratory conditions, f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbdef2e623eac1431c7ea0fa93820798
https://doi.org/10.1016/j.sajb.2020.09.023
https://doi.org/10.1016/j.sajb.2020.09.023
Autor:
Clinton G. L. Veale
Publikováno v:
ChemMedChem. 16:1199-1225
Modern medicinal chemistry is a complex, multidimensional discipline that operates at the interface of the chemical and biological sciences. The medicinal chemistry contribution to drug discovery is typically described in the context of the well-reci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3e36836707681c990267ab5b72922fa
https://doi.org/10.1002/cmdc.202000929
https://doi.org/10.1002/cmdc.202000929