Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Clinton E. Canal"'
Publikováno v:
ACS Chemical Neuroscience. 13:3629-3640
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cc91a419161e00d541aa6b2199acb80
https://doi.org/10.1021/acschemneuro.2c00574
https://doi.org/10.1021/acschemneuro.2c00574
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Central Nervous System Pharmacology - Behavioral.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2eb17d84b545e14562210fc152a1198b
https://doi.org/10.1124/jpet.122.145310
https://doi.org/10.1124/jpet.122.145310
Autor:
Jessica L. Armstrong, Clinton E. Canal
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c97157186931a094a7981cdc8eb0aa6c
https://doi.org/10.1096/fasebj.2022.36.s1.r2453
https://doi.org/10.1096/fasebj.2022.36.s1.r2453
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9086099119fb38f7958d45251bd2d206
https://doi.org/10.1096/fasebj.2022.36.s1.r4662
https://doi.org/10.1096/fasebj.2022.36.s1.r4662
Autor:
Jessica L Armstrong, Munmun Mukherjee, Tanishka S Saraf, Clinton E. Canal, Austen B. Casey, Raymond G. Booth
Publikováno v:
ACS Pharmacology & Translational Science. 3:509-523
Fragile X syndrome (FXS) is a neurodevelopmental disorder characterized by intellectual disabilities and a plethora of neuropsychiatric symptoms. FXS is the leading monogenic cause of autism spectrum disorder (ASD), which is defined clinically by rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29f72af055b9d0e133cde169f99ca41c
https://doi.org/10.1021/acsptsci.9b00101
https://doi.org/10.1021/acsptsci.9b00101
Autor:
Yiming Chen, Clinton E. Canal
Publikováno v:
ACS Chemical Neuroscience. 11:960-968
Synthetic cathinones (SCs) are designer, psychostimulant drugs of abuse that primarily act on monoamine transporters; little is known about their off-target liability. Abuse of pyrrolidine-containi...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2474708e8547b82ac993ab43c928c1f
https://doi.org/10.1021/acschemneuro.0c00008
https://doi.org/10.1021/acschemneuro.0c00008
Publikováno v:
Biochem Pharmacol
Blockade of the serotonin 5-HT(2A) G protein-coupled receptor (5-HT(2A)R) is a fundamental pharmacological characteristic of numerous antipsychotic medications, which are FDA-approved to treat schizophrenia, bipolar disorder, and as adjunctive therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e89712418e501d3885e3a78a354c838b
https://pubmed.ncbi.nlm.nih.gov/35381208
https://pubmed.ncbi.nlm.nih.gov/35381208
Publikováno v:
Epilepsy Res
The prevalence of seizures in individuals with fragile X syndrome (FXS) is ~25%; however, there are no reports of spontaneous seizures in the Fmr1 knockout mouse model of FXS. Herein, we report that 48% of adult (median age P96), Fmr1 knockout mice f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28b24495b7aa78c9dd36cdf79e6f581c
https://pubmed.ncbi.nlm.nih.gov/35290907
https://pubmed.ncbi.nlm.nih.gov/35290907
Autor:
Luis F. Restrepo, Erin C. Berthold, Aidan J. Hampson, Avi Patel, Lance R. McMahon, Carolina Lopera-Londoño, Takato Hiranita, Shyam H. Kamble, Samuel Obeng, Abhisheak Sharma, Lea R. Gamez-Jimenez, Francisco León, Clinton E. Canal, Marco Mottinelli, Christopher R. McCurdy, Yiming Chen, Tamara I. King
Publikováno v:
J Med Chem
Kratom alkaloids have mostly been evaluated for their opioid activity but less at other targets that could contribute to their physiological effects. Here, we investigated the in vitro and in vivo activity of kratom alkaloids at serotonin receptors (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749b326c3ebef7e4aed6ae82cdd6614a
https://europepmc.org/articles/PMC9235362/
https://europepmc.org/articles/PMC9235362/
Autor:
Clinton E. Canal, Marcello Leopoldo
Publikováno v:
ACS Chemical Neuroscience. 13:185-186
The molecular characterization of bioactive molecules, for example, small molecules targeting G-protein-coupled receptors, is evolving in complexity, impacting the meaning of terms like "agonist", "antagonist", and "selective", which, in the absence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9342f03b7e8bc3b5321719560ae64814
https://doi.org/10.1021/acschemneuro.1c00829
https://doi.org/10.1021/acschemneuro.1c00829