Induced pluripotent stem cell reprogramming-associated methylation at the GABRA2 promoter and chr4p12 GABA(A) subunit gene expression in the context of alcohol use disorder

Autor: Goetjen, Alexandra, Watson, Maegan, Lieberman, Richard, Clinton, Kaitlin, Kranzler, Henry R., Covault, Jonathan

Publikováno v: Am J Med Genet B Neuropsychiatr Genet

Twin studies indicate that there is a significant genetic contribution to the risk of developing alcohol use disorder (AUD). With the exception of coding variants in ADH1B and ALDH2, little is known about the molecular effects of AUD-associated loci.

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https://europepmc.org/articles/PMC8022112/

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Induced pluripotent stem cell reprogramming‐associated methylation at the GABRA2 promoter and chr4p12 GABAA subunit gene expression in the context of alcohol use disorder.

Autor: Goetjen, Alexandra, Watson, Maegan, Lieberman, Richard, Clinton, Kaitlin, Kranzler, Henry R., Covault, Jonathan

Publikováno v: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics; Dec2020, Vol. 183 Issue 8, p464-474, 11p

Induced pluripotent stem cell reprogramming‐associated methylation at the GABRA2promoter and chr4p12 GABAAsubunit gene expression in the context of alcohol use disorder

Autor: Goetjen, Alexandra, Watson, Maegan, Lieberman, Richard, Clinton, Kaitlin, Kranzler, Henry R., Covault, Jonathan

Publikováno v: American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics: The Official Publication of the International Society of Psychiatric Genetics; December 2020, Vol. 183 Issue: 8 p464-474, 11p