Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Clint M Upchurch"'
Autor:
Alex J B Kreutzberger, Volker Kiessling, Catherine A Doyle, Noah Schenk, Clint M Upchurch, Margaret Elmer-Dixon, Amanda E Ward, Julia Preobraschenski, Syed S Hussein, Weronika Tomaka, Patrick Seelheim, Iman Kattan, Megan Harris, Binyong Liang, Anne K Kenworthy, Bimal N Desai, Norbert Leitinger, Arun Anantharam, J David Castle, Lukas K Tamm
Publikováno v:
eLife, Vol 9 (2020)
Insulin secretion from β-cells is reduced at the onset of type-1 and during type-2 diabetes. Although inflammation and metabolic dysfunction of β-cells elicit secretory defects associated with type-1 or type-2 diabetes, accompanying changes to insu
Externí odkaz:
https://doaj.org/article/6a3003b24de34ef2a6a794b8fb9446e1
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Heme degradation by the heme oxygenase (HMOX) family of enzymes is critical for maintaining homeostasis and limiting heme-induced tissue damage. Macrophages express HMOX1 and 2 and are critical sites of heme degradation in healthy and diseased states
Externí odkaz:
https://doaj.org/article/87d8bc2ff8f8423cbc165739e69ff514
Autor:
Subramanian Senthivinayagam, Vlad Serbulea, Clint M. Upchurch, Renata Polanowska-Grabowska, Suresh K. Mendu, Srabani Sahu, Prathiba Jayaguru, Kevin W. Aylor, Mahendra D. Chordia, Limor Steinberg, Nathaniel Oberholtzer, Seichii Uchiyama, Noriko Inada, Ulrike M. Lorenz, Thurl E. Harris, Susanna R. Keller, Akshaya K. Meher, Alexandra Kadl, Bimal N. Desai, Bijoy K. Kundu, Norbert Leitinger
Publikováno v:
Molecular Metabolism, Vol 44, Iss , Pp 101130- (2021)
Objective: Brown adipose tissue (BAT) is specialized in thermogenesis. The conversion of energy into heat in brown adipocytes proceeds via stimulation of β-adrenergic receptor (βAR)-dependent signaling and activation of mitochondrial uncoupling pro
Externí odkaz:
https://doaj.org/article/3bac5da2881d485a8632564ecf041a48
Autor:
Scott Yeudall, Clint M. Upchurch, Philip V. Seegren, Caitlin M. Pavelec, Jan Greulich, Michael C. Lemke, Thurl E. Harris, Bimal N. Desai, Kyle L. Hoehn, Norbert Leitinger
Publikováno v:
Science Advances. 8
Acetyl-CoA carboxylase (ACC) regulates lipid synthesis; however, its role in inflammatory regulation in macrophages remains unclear. We generated mice that are deficient in both ACC isoforms in myeloid cells. ACC deficiency altered the lipidomic, tra
Autor:
Clint M. Upchurch, Scott Yeudall, Caitlin M. Pavelec, Dennis Merk, Jan Greulich, Mohan Manjegowda, Shyam S. Raghavan, Irina M. Bochkis, Michael M. Scott, Edward Perez-Reyes, Norbert Leitinger
Publikováno v:
Science advances. 8(28)
Oxidized phosphatidylcholines (OxPCs) are implicated in chronic tissue damage. Hyperlipidemic LDL-R-–deficient mice transgenic for an OxPC-recognizing IgM fragment (scFv-E06) are protected against nonalcoholic fatty liver disease (NAFLD). To examin
Autor:
Clint M. Upchurch, Scott Yeudall, Caitlin M. Pavelec, Mohan Manjegowda, Irina M. Bochkis, Michael Scott, Edward Perez‐Reyes, Norbert Leitinger
Publikováno v:
The FASEB Journal. 36
Autor:
Melissa D. Lempicki, Vlad Serbulea, Saikat Paul, Clint M. Upchurch, Srabani Sahu, Jake A. Gray, Gorav Ailawadi, Brandon L. Garcia, Coleen McNamara, Norbert Leitinger, Akshaya K. Meher
Publikováno v:
The FASEB Journal. 36
Autor:
Nicole M. Gilbertson, Natalie Z.M. Eichner, Julian M. Gaitán, John M. Pirtle, Jennifer L. Kirby, Clint M. Upchurch, Norbert Leitinger, Steven K. Malin
Publikováno v:
Physiol Behav
The objective of this study was to test if a low-calorie diet plus interval exercise (LCD+INT) reduced oxidized and non-oxidized phospholipids in relation to improved weight-related quality of life (QoL) to a greater extent than an energy-deficit mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a168a47e3cc53a52a6ddb94306a66d34
https://europepmc.org/articles/PMC8821381/
https://europepmc.org/articles/PMC8821381/
Autor:
Renata Polanowska-Grabowska, Srabani Sahu, Norbert Leitinger, Noriko Inada, Alexandra Kadl, Subramanian Senthivinayagam, Nathaniel P. Oberholtzer, Kevin W. Aylor, Susanna R. Keller, Ulrike M. Lorenz, Bimal N. Desai, Seichii Uchiyama, Vlad Serbulea, Thurl E. Harris, Limor Steinberg, Bijoy Kundu, Prathiba Jayaguru, Clint M Upchurch, Suresh K. Mendu, Akshaya K. Meher, Mahendra D. Chordia
Publikováno v:
Molecular Metabolism, Vol 44, Iss, Pp 101130-(2021)
Molecular Metabolism
Molecular Metabolism
Objective Brown adipose tissue (BAT) is specialized in thermogenesis. The conversion of energy into heat in brown adipocytes proceeds via stimulation of β-adrenergic receptor (βAR)-dependent signaling and activation of mitochondrial uncoupling prot
Autor:
Syed S Hussein, Anne K. Kenworthy, Megan T. Harris, Alex J. B. Kreutzberger, Margaret Elmer-Dixon, Arun Anantharam, Volker Kiessling, Bimal N. Desai, Julia Preobraschenski, Iman Kattan, Norbert Leitinger, Noah A. Schenk, Amanda E. Ward, Patrick Seelheim, Catherine A. Doyle, Clint M Upchurch, Binyong Liang, J. David Castle, Weronika Tomaka, Lukas K. Tamm
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Insulin secretion from β-cells is reduced at the onset of type-1 and during type-2 diabetes. Although inflammation and metabolic dysfunction of β-cells elicit secretory defects associated with type-1 or type-2 diabetes, accompanying changes to insu