Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Clint J. Winkler"'
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10166 (2010)
Groucho (Gro) is a Drosophila melanogaster transcriptional corepressor that directly interacts with the histone deacetylase Rpd3. Although previous studies suggest that this interaction is required for repression of Gro-responsive reporters in cultur
Externí odkaz:
https://doaj.org/article/d07e47643464429bb9b2ec7f9bc18b67
Publikováno v:
Biologicals. 41:176-183
Nanofiltration assures that protein therapeutics are free of adventitious agents such as viruses. Nanofilter pores must allow passage of protein drugs but be small enough to retain viruses. Five nanofilters have been evaluated to identify those that
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization. 42(5)
Nanofiltration is incorporated into the manufacturing processes of many protein biopharmaceuticals to enhance safety by providing the capacity to retain pathogens while allowing protein drugs to pass through the filter. Retention is mainly a function
Autor:
Dennis Kuo, Claudia Nieva, Clint J. Winkler, Sergio González-Crespo, Gerardo Jiménez, Albert J. Courey, Aharon Helman, Leiore Ajuria, Ze'ev Paroush, María José Andreu, Núria Samper
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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et al.
RTK/Ras/MAPK signaling pathways play key functions in metazoan development, but how they control expression of downstream genes is not well understood. In Drosophila, it is generally assumed that most transcriptional responses to RTK sign
RTK/Ras/MAPK signaling pathways play key functions in metazoan development, but how they control expression of downstream genes is not well understood. In Drosophila, it is generally assumed that most transcriptional responses to RTK sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e39a53b0211278530636408151eb503
https://europepmc.org/articles/PMC3035094/
https://europepmc.org/articles/PMC3035094/
Publikováno v:
The FASEB Journal. 24
Autor:
Peleg Hasson, Clint J. Winkler, Talila Volk, Albert J. Courey, Ze'ev Paroush, Nirit Egoz, Tama Dinur, Songtao Jia, Gloria Volohonsky
Publikováno v:
Nature genetics. 37(1)
Crosstalk between signaling pathways is crucial for the generation of complex and varied transcriptional networks. Antagonism between the EGF-receptor (EGFR) and Notch pathways in particular is well documented, although the underlying mechanism is po