Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Clint Gray"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract The adaptability of glioblastoma (GBM) cells, encouraged by complex interactions with the tumour microenvironment (TME), currently renders GBM an incurable cancer. Despite intensive research, with many clinical trials, GBM patients rely on s
Externí odkaz:
https://doaj.org/article/e7e4e6c2f4ec42e0acf2fa0cb7cc91e3
Autor:
Ryan Phillip Sixtus, Clint Gray, Heather Barnes, Emily Sarah Jane Paterson, Mary Judith Berry, Rebecca Maree Dyson
Publikováno v:
Physiological Reports, Vol 12, Iss 20, Pp n/a-n/a (2024)
Abstract Adversity early in life can modify the trajectory for disease risk extending decades beyond the event. Preterm birth produces persistent cardiovascular alterations that may appear maladaptive in adulthood. We have previously hypothesized tha
Externí odkaz:
https://doaj.org/article/72d60886a9c844d39a13a8fd4382fa80
Publikováno v:
Organoids, Vol 2, Iss 4, Pp 218-230 (2023)
Meningiomas are the most common tumours of the central nervous system. According to the World Health Organization (WHO), this disease is classified into three different grades: 80% of meningioma patients present with benign grade I tumours, while les
Externí odkaz:
https://doaj.org/article/8a02d45259de441a8a333e8a38387d2d
Publikováno v:
Experimental Physiology, Vol 108, Iss 8, Pp 1011-1025 (2023)
Abstract Preterm‐born individuals are a uniquely vulnerable population. Preterm exposure to the extrauterine environment and the (mal)adaptations that occur during the transitional period can result in alterations to their macro‐ and micro‐phys
Externí odkaz:
https://doaj.org/article/45e340c36ca24803b9d98dd9e6ad0195
Publikováno v:
Organoids, Vol 2, Iss 1, Pp 37-49 (2023)
Organoids are 3D organ-like structures grown from stem cells in vitro that mimic the organ or disease from which they are derived. Due to their stem cell origin, organoids contain a heterogeneous population of cells reflecting the diversity of cell t
Externí odkaz:
https://doaj.org/article/bd5eb01dba244a449506ca298d185ae1
Publikováno v:
Cells, Vol 12, Iss 1, p 153 (2022)
Glioblastoma, a grade IV astrocytoma, is regarded as the most aggressive primary brain tumour with an overall median survival of 16.0 months following the standard treatment regimen of surgical resection, followed by radiotherapy and chemotherapy wit
Externí odkaz:
https://doaj.org/article/a12e273e928c4f5f90ad914579e4e918
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2988 (2022)
Cancer metastasis and treatment resistance are the main causes of treatment failure and cancer-related deaths. Their underlying mechanisms remain to be fully elucidated and have been attributed to the presence of cancer stem cells (CSCs)—a small po
Externí odkaz:
https://doaj.org/article/63ec873e4db74985b27786c02027ac5e
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 1, Pp n/a-n/a (2021)
Abstract Anesthesia is frequently used to facilitate physiological monitoring during interventional animal studies. However, its use may induce cardiovascular (central and peripheral), respiratory, and thermoregulatory depression, confounding results
Externí odkaz:
https://doaj.org/article/18807300065c4359b4e191a32fd12e0b
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Excess dietary fructose is a major public health concern (1–4). Evidence shows increased fructose intake can cause insulin resistance, hepatic de novo lipogenesis, hypertriglyceridemia, obesity and non-alcoholic fatty liver disease (NAFLD) (5–9).
Externí odkaz:
https://doaj.org/article/f03cc5845acc462bbf4e21f2039eefcc
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The developmental origins of health and disease hypothesis proposes that an adverse early life environment, including in utero exposure to a maternal obesogenic environment, can lead to an increased long-term risk of obesity and related meta
Externí odkaz:
https://doaj.org/article/667882bdeb1143d3a26eeccc6b5df699