Stable warfarin dose prediction in sub‐Saharan African patients: A machine‐learning approach and external validation of a clinical dose–initiation algorithm

Autor: Innocent G. Asiimwe, Marc Blockman, Karen Cohen, Clint Cupido, Claire Hutchinson, Barry Jacobson, Mohammed Lamorde, Jennie Morgan, Johannes P. Mouton, Doreen Nakagaayi, Emmy Okello, Elise Schapkaitz, Christine Sekaggya‐Wiltshire, Jerome R. Semakula, Catriona Waitt, Eunice J. Zhang, Andrea L. Jorgensen, Munir Pirmohamed

Publikováno v: CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 1, Pp 20-29 (2022)

Abstract Warfarin remains the most widely prescribed oral anticoagulant in sub‐Saharan Africa. However, because of its narrow therapeutic index, dosing can be challenging. We have therefore (a) evaluated and compared the performance of 21 machine�

Externí odkaz: https://doaj.org/article/a70a4a18bb0f45898c40e56846101497

The utility of a shortened palliative care screening tool to predict death within 12 months – a prospective observational study in two south African hospitals with a high HIV burden

Autor: Peter J. Raubenheimer, Cascia Day, Faried Abdullah, Katherine Manning, Clint Cupido, Jonny Peter

Publikováno v: BMC Palliative Care, Vol 18, Iss 1, Pp 1-8 (2019)

Abstract Background Timely identification of people who are at risk of dying is an important first component of end-of-life care. Clinicians often fail to identify such patients, thus trigger tools have been developed to assist in this process. We ai

Externí odkaz: https://doaj.org/article/1ee18660bb93433a8300324a5d226e69

The utility of a shortened palliative care screening tool to predict death within 12 months – a prospective observational study in two south African hospitals with a high HIV burden

Autor: Faried Abdullah, Peter J Raubenheimer, Jonny Peter, Katherine Manning, Cascia Day, Clint Cupido

Publikováno v: BMC Palliative Care, Vol 18, Iss 1, Pp 1-8 (2019)
BMC Palliative Care

Background Timely identification of people who are at risk of dying is an important first component of end-of-life care. Clinicians often fail to identify such patients, thus trigger tools have been developed to assist in this process. We aimed to ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965f86f8210f0943ffb0ebf32461869c
http://link.springer.com/article/10.1186/s12904-019-0487-5

Profile and anticoagulation outcomes of patients on warfarin therapy in an urban hospital in Cape Town, South Africa

Autor: Clint Cupido, D Hellenberg, Babatunde O. Sonuga, Cilia Jaeger

Publikováno v: African Journal of Primary Health Care & Family Medicine, Vol 8, Iss 1, Pp e1-e8 (2016)
African Journal of Primary Health Care & Family Medicine, Volume: 8, Issue: 1, Pages: 1-8, Published: 2016
African Journal of Primary Health Care & Family Medicine

Background: Warfarin is the most frequently used oral anticoagulant worldwide and it is the oral anticoagulant of choice in South Africa for reducing thrombosis-related morbidity and mortality. However, the safety and efficacy of warfarin therapy dep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb83b58bb7a37f8b9ae58977aa27afc0
https://phcfm.org/index.php/phcfm/article/view/1032

A hospital-based palliative care service for patients with advanced organ failure in sub-Saharan Africa reduces admissions and increases home death rates

Autor: Liz Gwyther, Motasim Badri, Taylor Desrosiers, Clint Cupido, Lindi van Niekerk, Elizabeth Pitout, Richard Harding

Publikováno v: Journal of pain and symptom management. 47(4)

Despite emerging data of cost savings under palliative care in various regions, no such data have been generated in response to the high burden of terminal illness in Africa.This evaluation of a novel hospital-based palliative care service for patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ab281387ac20bbd6892bf4871d656f
https://pubmed.ncbi.nlm.nih.gov/23969328